Publications by authors named "Wenqiang Xue"
Article Synopsis
- Thoracic epidural anesthesia (TEA) may protect the lungs during surgery by lowering driving pressure (ΔP), which is linked to a decrease in postoperative pulmonary complications (PPCs).
- This study involved adult patients undergoing major upper abdominal surgery, comparing those who received TEA combined with general anesthesia to those who only had general anesthesia.
- Results showed the TEA group had significantly lower ΔP values, indicating potential lung protection, though the overall incidence of PPCs was not significantly different between the two groups; however, atelectasis occurred less frequently in the TEA group.
Article Synopsis
- This study investigates the effectiveness of three types of nerve blocks (ESPB, RLB, and TPVB) for managing pain after thoracic surgery.
- The research involved 76 patients and measured pain levels using a Numeric Rating Scale over 24 hours, along with other factors like opioid use and recovery.
- Results showed that ESPB and RLB were just as effective as TPVB in controlling pain without significant differences in side effects or recovery outcomes.
Article Synopsis
- The study explores the role of endothelial glycocalyx (EG) deterioration in ventilator-induced lung injury (VILI) using male Sprague-Dawley rats.
- Researchers found that high tidal volume ventilation leads to the breakdown of EG, evidenced by increased glycocalyx components in plasma and decreased syndecan-1 in lung tissues.
- The findings suggest that inflammation and signaling pathways, particularly NF-κB, play a role in EG degradation during VILI, providing insights for potential therapeutic interventions.
Article Synopsis
- - The meta-analysis investigated how goal-directed fluid therapy (GDFT) affects postoperative complications in patients undergoing one-lung ventilation (OLV) during thoracic surgery, revealing mixed previous findings.
- - Researchers analyzed data from 11 studies involving 1,318 patients, assessing various outcomes including complication rates, hospital stay length, and inflammatory factors, with the quality of studies evaluated for reliability.
- - Results showed that GDFT significantly reduced the incidence of postoperative complications and fluid infusion, suggesting it leads to better recovery and survival outcomes in thoracic surgery for OLV patients.
Background: Hypoxemia and fluctuations in respiratory mechanics parameters are common during one-lung ventilation (OLV) in thoracic surgery. Additionally, the incidence of postoperative pulmonary complications (PPC) in thoracic surgery is higher than that in other surgeries. Previous studies have demonstrated that driving pressure-oriented ventilation can reduce both mortality in patients with acute respiratory distress syndrome (ARDS) and the incidence of PPC in patients undergoing general anesthesia.
View Article and Find Full Text PDFPreparation, Properties, and Application of Graphene-Based Materials in Tissue Engineering Scaffolds.
Tissue Eng Part B Rev
October 2022
Tissue engineering has a great application prospect as an effective treatment for tissue and organ injury, functional reduction, or loss. Bioactive tissues are reconstructed and damaged organs are repaired by the three elements, including cells, scaffold materials, and growth factors. Graphene-based composites can be used as reinforcing auxiliary materials for tissue scaffold preparation because of their large specific surface area, and good mechanical support.
View Article and Find Full Text PDFWith increasing knowledge about diseases at the histological, cytological to sub-organelle level, targeting organelle therapy has gradually been envisioned as an approach to overcome the shortcomings of poor specificity and multiple toxic side effects on tissues and cell-level treatments using the currently available therapy. Organelle carbon dots (CDs) are a class of functionalized CDs that can target organelles. CDs can be prepared by a "synchronous synthesis method" and "asynchronous modification method.
View Article and Find Full Text PDFBackground: There is an increasing body of evidence associating traditional cardiovascular risk factors with atrial fibrillation (AF), but the relationship between blood lipid profiles and the risk of AF remains controversial.
Objective: This study aimed to conduct a systemic review and meta-analysis of large cohort studies to evaluate the relationship between blood lipid profiles and incident AF.
Methods: PubMed and Embase were searched up to January 31, 2019, for cohort studies that reported the relationship between blood lipid levels and incident AF.