Human disturbance increases spatiotemporal associations among mountain forest terrestrial mammal species.

Spatial and temporal associations between sympatric species underpin biotic interactions, structure ecological assemblages, and sustain ecosystem functioning and stability. However, the resilience of interspecific spatiotemporal associations to human activity remains poorly understood, particularly in mountain forests where anthropogenic impacts are often pervasive. Here, we applied context-dependent Joint Species Distribution Models to a systematic camera-trap survey dataset from a global biodiversity hotspot in eastern Himalayas to understand how prominent human activities in mountain forests influence species associations within terrestrial mammal communities.

New records of the white-cheeked macaque provide range extension for the endangered primate in Gaoligong Mountains.

White-cheeked macaque Macaca leucogenys is a recently described primate species discovered by camera-trap surveys in the Medog region in 2015. The species was thought to be narrowly distributed in southeastern Tibet. However, knowledge on the distribution and conservation of the species is quite limited.

Disproportionate loss of threatened terrestrial mammals along anthropogenic disturbance gradients.

Tens of thousands of species are increasingly confronted with habitat degradation and threatened with local extirpation and global extinction as a result of human activities. Understanding the local processes that shape the regional distribution patterns of at-risk species is useful in safeguarding species against threats. However, there is only limited understanding of the processes that shape the regional distribution patterns of threatened species.

Synthesis of Mg Alkoxide Nanowires from Mg Alkoxide Nanoparticles upon Ligand Exchange.

We report on a new synthesis pathway for Mg -propoxide nanowires (NWs) from Mg ethoxide nanoparticles using a simple alkoxy ligand exchange reaction followed by condensation polymerization in -propanol. In order to uncover the morphology-structure correlation in the metal alkoxide family, we employed a powerful range of state-of-the-art characterization techniques. The morphology transformation from nanoparticles to nanowires was demonstrated by time-lapse SEM micrographs.

Functional diversity loss and change in nocturnal behavior of mammals under anthropogenic disturbance.

In the Anthropocene, understanding the impacts of anthropogenic influence on biodiversity and behavior of vulnerable wildlife communities is increasingly relevant to effective conservation. However, comparative studies aimed at disentangling the concurrent effect of different types of human disturbance on multifaceted biodiversity and on activity patterns of mammals are surprisingly rare. We applied a multiregion community model to separately estimate the effects of cumulative human modification (e.

Aldehyde dehydrogenase 1 expression correlates with clinicopathologic features of patients with breast cancer: a meta-analysis.

A number of studies have investigated the relationship between aldehyde dehydrogenase 1 (ALDH1) expression and the clinical pathological features of the patients with breast cancer. However, conclusions reported by different parties seem to be inconsistent. We have reviewed published studies and carried out this meta-analysis to provide credible results.

Plumbagin inhibits growth of gliomas in vivo via suppression of FOXM1 expression.

Plumbagin is a natural compound that is isolated from the root of the medicinal plant Plumbago zeylanica L. Based on a previous in vitro study performed by our group, which demonstrated the effectiveness of plumbagin against glioma cells, we further ascertained whether plumbagin exhibits the same effectiveness against glioma cell xenografts in nude mice. Our results revealed that tumor volume was reduced by 54.

Plumbagin induces growth inhibition of human glioma cells by downregulating the expression and activity of FOXM1.

Plumbagin, a natural quinonoid constituent isolated from the root of medicinal plant Plumbago zeylanica L, has exhibited anti-tumor and anti-proliferative activities in various tumor cell lines as well as in animal tumor models. However, its anticancer effects and the mechanisms underlying its suppression of glioma cell growth have not been elucidated. Oncogenic transcription factor Forkhead Box M1 (FOXM1) has garnered particular interest in recent years as a potential target for the prevention and/or therapeutic intervention in glioma, nevertheless, less information is currently available regarding FOXM1 inhibitor.