Publications by authors named "Wenpei Zheng"

The overall structural integrity plays a vital role in the unique performance of living organisms, but the integral synchronous preparation of different multiscale architectures remains challenging. Inspired by the cuttlebone's rigid cavity-wall structure with excellent energy absorption, we develop a robust hierarchical predesigned hydrogel assembly strategy to integrally synchronously assemble multiple organic and inorganic micro-nano building blocks to different structures. The two types of predesigned hydrogels, combined with hydrogen, covalent bonding, and electrostatic interactions, are layer-by-layer assembled into brick-and-mortar structures and close-packed rigid micro hollow structures in a cuttlebone-inspired structural material, respectively.

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Article Synopsis
  • - The study compared two methods for inducing labor in first-time mothers: dinoprostone vaginal insert (PROPESS) and double balloon cook catheter (DBC), with a focus on delivery outcomes.
  • - Results showed similar overall vaginal delivery rates, but PROPESS had a significantly higher rate of successful vaginal deliveries within 24 hours compared to DBC (55.45% vs. 38.43%).
  • - While DBC had a higher occurrence of complications like chorioamnionitis and required more oxytocin for labor augmentation, neonatal outcomes were similar in both groups.
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Objective: To investigate the associations of Insulin-like growth factor-II (IGF2) gene, Insulin-like growth factor-II receptor (IGF2R) gene and Insulin-like growth factor-II binding protein 2 (IGF2BP2) gene polymorphisms with the susceptibility to gestational diabetes mellitus (GDM) in Chinese population.

Methods: A total of 1703 pregnant women (835 GDM and 868 Non-GDM) were recruited in this case-control study. All participants underwent prenatal 75 g oral glucose tolerance test (OGTT) examinations during 24-28 gestational weeks at the Maternal and Child Health Hospital of Hubei Province from January 15, 2018 to March 31, 2019.

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Objective: To investigate the correlation between transcription factor 7-like 2 (TCF7L2) gene polymorphisms and gestational diabetes mellitus (GDM) risk in the central Chinese population.

Methods: This case-control study examined the association of seven gene single-nucleotide polymorphisms (SNPs) (rs11196218, rs4506565, rs7895340, rs7901695, rs11196205, rs12243326, and rs290487) with GDM risk in the central Chinese population (843 GDM and 877 controls). The clinical information and blood samples were collected by trained interviewers and nurses.

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Purpose: The aim of the study was to find out the associations of Melatonin receptor 1B () genetic variants with gestational diabetes mellitus (GDM) in Wuhan of central China.

Patients And Methods: A hospital-based case-control study that included 1679 women was carried out to explore the associations of single nucleotide polymorphisms (SNPs) with GDM risk, which were analyzed through logistic regression analysis by adjusting age, pre-pregnancy BMI and family history of diabetes. Multifactor dimensionality reduction was applied to determine gene-gene interactions between SNPs.

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Objectives: The aim of this study was to investigate the association of glucokinase (GCK) gene, glucokinase regulatory protein (GCKR) gene polymorphisms with the susceptibility to GDM in Chinese population.

Research Design And Methods: This case-control study included 835 GDM patients and 870 non-diabetic pregnant women who had their prenatal examinations at 24-28 gestational weeks at the Maternal and Child Health Hospital of Hubei Province from January 15, 2018 to March 31, 2019. The nurses were trained to collect clinical information and blood samples.

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