Recombinant virus expressing hIFN-λ1 (rL-hIFN-λ1) has important effects on endoplasmic reticulum stress, autophagy and apoptosis in small cell lung cancer.

Background: Small cell lung cancer (SCLC) is an aggressive tumor with a poor prognosis. Human IFN-λ1 (IL-29), belonging to the type III IFN family, captured increasing attention recently due to its crucial role in developing tumors. Recent studies have revealed that the recombinant Newcastle Disease Virus (NDV) expressing human IFN-λ1 (rL-hIFN-λ1) plays a critical role in the development of tumors.

Inverted Aortic Prosthesis in the Mitral Position: Is Upside Down Always the Right Side Up?

Evaluation of prosthetic valve function is a challenging task. The clinician has to employ multiple parameters to quantify dysfunction (if present), the results of which can be mutually discrepant. This results from heterogeneity in the design of the valves themselves, implantation techniques, and both intra- and interpatient hemodynamic variability.

Intraoperative 3-Dimensional Echocardiography-Derived Right Ventricular Volumetric Analysis in Chronic Thromboembolic Pulmonary Hypertension Patients Before and After Pulmonary Thromboendarterectomy.

Objectives: To assess the change in 3-dimensional (3D) echocardiography-derived right ventricular volumes before and after pulmonary thromboendarterectomy (PTE) and to evaluate the correlation of these variables with right heart catheterization-calculated pulmonary vascular resistance (PVR).

Setting: Single university hospitals.

Participants: Patients undergoing elective PTE surgery between November 2016 and February 2018.

A study on microwave-assisted fast co-pyrolysis of chlorella and tire in the N and CO atmospheres.

The microwave-assisted fast co-pyrolysis of chlorella and tire with additive under N and CO atmospheres were investigated. The pyrolysis profiles, yields of three-phase, the chemical composition of liquid and the ultimate analyses of solid residues were gained. With the tire ratio increasing, all the characters had the changes.

Ultrasonic pretreatment effects on the co-pyrolysis of municipal solid waste and paper sludge through orthogonal test.

In this study, the influences of ultrasonic pretreatment factors (frequency, power, treatment time) on blends of municipal solid waste (MSW) and paper sludge (PS) with additive (MgO) was explored, through orthogonal experiments design. The optimum operating condition wanted to be acquired. However, for the ultimate (H/C) and ash analysis after pretreatment, solid residue mass and oxygenates compounds contents in products, the influences of factors were in different results.

Activation of glycosyl trichloroacetimidates with perchloric acid on silica (HClO(4)-SiO(2)) provides enhanced alpha-selectivity.

Obtaining high stereoselectivity in glycosylation reactions is often challenging in the absence of neighboring group participation. In this study, we demonstrate that activation of glycosyl trichloroacetimidate donors with immobilized perchloric acid on silica (HClO(4)-SiO(2)) provides higher alpha-selectivity than trimethylsilyl triflate (TMSOTf) for reactions that do not involve neighboring group participation.