Family Resilience in Patients With Schizophrenia: Potential Influencing Factors and Mediating Effect.

Objective: To identify the determinants of family resilience in the recovery of individuals with schizophrenia using Walsh's family resilience framework.

Design: A cross-sectional study.

Methods: In Northeast China, 403 patients diagnosed with schizophrenia were enrolled for this study, assessing family resilience, family communication, social support, illness knowledge, hope and family functioning.

Classification of psychosis spectrum disorders using graph convolutional networks with structurally constrained functional connectomes.

This article considers the problem of classifying individuals in a dataset of diverse psychosis spectrum conditions, including persons with subsyndromal psychotic-like experiences (PLEs) and healthy controls. This task is more challenging than the traditional problem of distinguishing patients with a diagnosed disorder from controls using brain network features, since the neurobiological differences between PLE individuals and healthy persons are less pronounced. Further, examining a transdiagnostic sample compared to controls is concordant with contemporary approaches to understanding the full spectrum of neurobiology of psychoses.

Highly Thermally Conductive Triple-Level Ordered CNT/PVA Nanofibrous Films.

The escalating thermal power density in electronic devices necessitates advanced thermal management technologies. Polymer-based materials, prized for their electrical insulation, flexibility, light weight, and strength, are extensively used in this field. However, the inherent low thermal conductivity of polymers requires enhancement for effective heat dissipation.

Relationship between medication burden and medication experience in stable patients with schizophrenia: the mediating effect of medication belief.

Background: Individuals with schizophrenia require prolonged antipsychotic medication treatment. But more than 50% of individuals with schizophrenia experience adverse medication experiences during their antipsychotic treatments. Such individuals often adjust or discontinue medication, leading to disease relapse and impaired social functioning.

Asymmetric Cyclodextrin-Dimer-Involved Nanoassemblies by Selective Host-Guest Interactions: Concentration-Dependent Morphology Evolution and Light-Regulated Biomedical Applications.

Supramolecular assembly has attracted significant attention and has been applied to various applications. Herein, a β-γ-CD dimer was synthesized to complex different guest molecules, including single-strand polyethylene glycol (PEG)-modified C (PEG-C), photothermal conversion reagent (IR780), and dexamethasone (Dexa), according to the complexation constant-dependent specific selectivity. Spherical or cylindrical nanoparticles, monolayer or bilayer vesicles, and bilayer fusion vesicles were discovered in succession if the concentration of PEG-C was varied.

Study on the behavior of clusters in the physical recovery of GaAs scrap.

Gallium arsenide (GaAs) is the most widely used second-generation semiconductor material. However, a large amount of GaAs scrap is generated at various stages of the GaAs wafer production process. Volatile GaAs clusters are inevitably generated during the process of GaAs vacuum thermal decomposition, resulting in lower purity of the recovered arsenic and the loss of gallium.

Construction and verification of aggressive behavior risk prediction model in stable patients with schizophrenia.

Background: Among all types of mental disorders, individuals with schizophrenia exhibit the highest frequency of aggressive behavior. This disrupts the healthcare environment and poses threats to family life and social harmony. Present approaches fail to identify individuals with schizophrenia who are predisposed to aggressive behavior.

A Case of Strange Arterial Embolism After Uterine Curettage.

Hysteroscopic local endometrial resection and curettage are common surgical procedures. Postoperative arterial thromboembolism is rare. However, coronary and renal embolism after the procedure has never been reported in the literature, so far.

Adjunctive repetitive transcranial magnetic stimulation for adolescents with first-episode major depressive disorder: a meta-analysis.

Objective: This meta-analysis of randomized clinical trials (RCTs) was conducted to explore the therapeutic effects, tolerability and safety of repetitive transcranial magnetic stimulation (rTMS) as an adjunct treatment in adolescents with first-episode major depressive disorder (FE-MDD).

Methods: RCTs examining the efficacy, tolerability and safety of adjunctive rTMS for adolescents with FE-MDD were included. Data were extracted by three independent authors and synthesized using RevMan 5.

Synergistic chemo-photo anticancer therapy by using reversible Diels-Alder dynamic covalent bond mediated polyprodrug amphiphiles and immunoactivation investigation.

Highly efficient endocytosis and multi-approach integrated therapeutic tactics are important factors in oncotherapy. With the aid of thermally reversible furan-maleimide dynamic covalent bonds and the "polyprodrug amphiphiles" concept, thermo- and reduction-responsive PEG(-COOH)Fu/MI(-SS-)CPT copolymers were fabricated by the Diels-Alder (D-A) coupling of hydrophilic Fu(-COOH)-PEG and hydrophobic MI(-SS-)-CPT building blocks. The copolymers could self-assemble to form composite nanoparticles with a photothermal conversion reagent (IR780) and maintain excellent stability.

Necrotic cardiac myocytes skew macrophage polarization towards a classically activated phenotype.

Necrotic and dying cells release damage-associated molecular patterns (DAMPs) that can initiate sterile inflammatory responses in the heart. Although macrophages are essential for myocardial repair and regeneration, the effect of DAMPs on macrophage activation remains unclear. To address this gap in knowledge we studied the effect of necrotic cardiac myocyte extracts on primary peritoneal macrophage (PPM) cultures in vitro.

A wearable platform for closed-loop stimulation and recording of single-neuron and local field potential activity in freely moving humans.

Advances in technologies that can record and stimulate deep brain activity in humans have led to impactful discoveries within the field of neuroscience and contributed to the development of novel therapies for neurological and psychiatric disorders. Further progress, however, has been hindered by device limitations in that recording of single-neuron activity during freely moving behaviors in humans has not been possible. Additionally, implantable neurostimulation devices, currently approved for human use, have limited stimulation programmability and restricted full-duplex bidirectional capability.

Elevated serum FGF21 levels predict heart failure during hospitalization of STEMI patients after emergency percutaneous coronary intervention.

Background: Fibroblast growth factor 21 (FGF21) has multiple cardioprotective effects including modulation of glucolipid metabolism, anti-inflammation, and anti-oxidative stress, but its association with the heart failure during hospitalization in patients with ST-segment elevation myocardial infarction (STEMI) undergoing emergency percutaneous coronary intervention (PCI) has not been reported.

Methods: A total of 348 STEMI patients treated with emergency PCI were included from January 2016 to December 2018. Relevant biochemical indicators were measured by central laboratory.

Template-Free Synthesis of Magnetic La-Mn-Fe Tri-Metal Oxide Nanofibers for Efficient Fluoride Remediation: Kinetics, Isotherms, Thermodynamics and Reusability.

The occurrence of fluoride contamination in drinking water has gained substantial concern owing to its serious threat to human health. Traditional adsorbents have shortcomings such as low adsorption capacity and poor selectivity, so it is urgent to develop new adsorbents with high adsorption capacity, renewable and no secondary pollution. In this work, magnetic electrospun La-Mn-Fe tri-metal oxide nanofibers (LMF NFs) for fluoride recovery were developed via electrospinning and heat treatment, and its defluoridation property was evaluated in batch trials.

Efficacy and safety of liraglutide in patients with type 2 diabetes mellitus and severe obstructive sleep apnea.

Objectives: To observe the efficacy and side effects of liraglutide in the treatment of type 2 diabetes mellitus (T2DM) patients with severe obstructive sleep apnea (OSA).

Methods: The study conducted in an outpatient setting was a two-center, prospective randomized controlled study. T2DM patients with severe OSA were randomized to the control group (continuous positive airway pressure [CPAP] and drug treatment without liraglutide) or the liraglutide group (CPAP and drug treatment including liraglutide).

Synergy of directional oxidation and vacuum gasification for green recovery of AsO from arsenic-containing hazardous secondary resources.

Arsenic, a hazardous material that is toxic for humans, enters the human body through soil, water, and air. Furthermore, metal smelting is known to produce arsenic-containing hazardous secondary resources (AHSRs), which cause irreversible damage to the total environment. Therefore, a novel, clean, and efficient arsenic fixation technology has been developed in this study for arsenic removal, which involves directional oxidation and vacuum gasification of AHSRs.

Outstanding fluoride removal from aqueous solution by a La-based adsorbent.

A La-based adsorbent was prepared with La(NO)·6HO, 2-methylimidazole and DMF amide-hydrolysis and used for fluoride decontamination from aqueous water. The obtained adsorbent was lanthanum methanoate (La(COOH)). The effects of pH value, initial F concentration and interfering ions on defluoridation properties of as-prepared La(COOH) were assessed through batch adsorption tests.

Predictive value of two different definitions of contrast-associated acute kidney injury for long-term major adverse kidney events in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.

Background: It remains controversial whether contrast-associated acute kidney injury (CA-AKI) is associated with long-term major adverse kidney events (MAKE) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).

Methods: By the Acute Kidney Injury Network (AKIN) criteria, CA-AKI was defined as an increase in serum creatinine ≥ 0.3 mg/dL or 50% from baseline within 48 h after PCI; or an increase in serum creatinine ≥ 0.