The removal of high Se(IV) and Cd(II) concentrations in sulfur autotrophic reactor based on the "hibernation-like microbial survival strategy".

The removal of selenite (Se(IV)) and cadmium (Cd(II)) from low-carbon wastewater presents significant challenges. However, the addition of external organic carbon sources is limited in application due to the high cost and potential for secondary pollution. This study introduced a "hibernation-like microbial survival strategy", enabling efficient removal of Se(IV) and Cd(II) in sulfur autotrophic reactor, with S acting as the electron donor.

Recent Developments in Drug Design of Oral Synthetic Free Fatty Acid Receptor 1 Agonists.

Over the past two decades, synthetic FFAR1 agonists such as TAK-875 and TSL1806 have undergone meticulous design and extensive clinical trials. However, due to issues primarily related to hepatotoxicity, no FFAR1 agonist has yet received regulatory approval. Research into the sources of hepatotoxicity suggests that one potential cause lies in the molecular structure itself.

Mesenchymal stem cell treatment alleviates seawater drowning induced lung injury by inhibiting the TNFα/Snail/EMT pathway.

Background: Seawater drowning (SWD) has been an escalating hazard in recent years. It can not only cause immediate death but can also inflict severe complications, such as acute lung injury (ALI), which greatly increases the mortality rate. Thus, investigating the mechanism of SWD induced lung injury and discovering effective treatments is of great importance.

Systematic Review and Meta-analysis of Acupuncture for Modulation of Immune and Inflammatory Markers in Cancer Patients.

Inflammation is associated with tumor initiation, and existing tumors are associated with immune suppression locally and systemically. Cancer treatment is also associated with immune suppression. This review evaluates evidence related to the use of acupuncture for modulation of inflammation and the immune system in cancer patients.

Study on the mechanism of regulating micromolar Fe utilization and promoting denitrification by guanosine monophosphate (GMP) based multi-signal functional material Hematin@Fe/GMP.

A novel multi-signal functional material consisting of Hematin, Fe, and guanosine monophosphate (GMP) was successfully constructed (Hematin@Fe/GMP) to enhance denitrification efficiency based on the signal network regulation of electron transfer, micromolar Fe utilization, and microbial community. Hematin@Fe/GMP enhanced nitrate reduction rate by 2.33-fold with a 9.

Effect of five lactic acid bacteria on the flavor quality of fermented sweet potato juice.

The purpose of this research was to assess the impact of 5 lactic acid bacteria (LAB), Lactiplantibacillus plantarum, Lacticaseibacillus casei, , Lacticaseibacillus rhamnosus and subsp. bulgaricus on the characteristic flavor of the fermented sweet potato juice. Following the fermentation process, significant variations were observed in the concentrations of sugars, organic acids, as well as the overall volatile aroma compounds.

Amorphous Cu/Fe nanoparticles with tandem intracellular and extracellular electron capacity for enhancing denitrification performance and recovery of co-contaminant suppressed denitrification.

In this study, a functionally stable insoluble Cu/Fe nanoparticles (Cu/Fe NPs) were synthesized and applied denitrification with different contaminants. The results showed that 50 mg/L Cu/Fe NPs increased NO-N reduction rate up to 14.3 mg/(L·h) about 3 folds compared with the control system (4.

Inflammatory crosstalk impairs phagocytic receptors and aggravates atherosclerosis in clonal hematopoiesis in mice.

Clonal hematopoiesis (CH) increases inflammasome-linked atherosclerosis but the mechanisms by which CH mutant cells transmit inflammatory signals to non-mutant cells are largely unknown. To address this question we transplanted 1.5% Jak2VF bone marrow (BM) cells with 98.

Influence of campus exclusion on bullying behavior of junior high school students: role of callous-unemotional traits and family caring.

School bullying significantly impacts adolescent physical and mental development. The current study aimed to explore the effect of campus exclusion on school bullying behavior among junior high school students and the role of callous-unemotional traits and family caring. The Campus Exclusion Questionnaire, Olweus Child Bullying Questionnaire, Callous-Unemotional Trait Scale, and Family Caring Scale were completed by 705 students.

Roseobacter sinensis sp. nov., a marine bacterium capable to synthesize arachidonic acid.

Strain WL0113 was isolated from surface seawater of the coast of Lianyungang, Jiangsu province, PR China. Strain WL0113 shared highest 16S rRNA gene sequence similarity with Roseobacter insulae YSTF-M11 (98.8%), followed by R.

On Matrix Representation of Extension Field GF() and Its Application in Vector Linear Network Coding.

For a finite field GF(pL) with prime and L>1, one of the standard representations is L×L matrices over GF() so that the arithmetic of GF(pL) can be realized by the arithmetic among these matrices over GF(). Based on the matrix representation of GF(pL), a conventional linear network coding scheme over GF(pL) can be transformed to an -dimensional vector LNC scheme over GF(). Recently, a few real implementations of coding schemes over GF(2L), such as the Reed-Solomon (RS) codes in the ISA-L library and the Cauchy-RS codes in the Longhair library, are built upon the classical result to achieve matrix representation, which focuses more on the structure of every individual matrix but does not shed light on the inherent correlation among matrices which corresponds to different elements.

Fe/GMP functional nanomaterial enhancing the denitrification efficiency by bi-signal regulation: Electron transfer and microbial community.

A novel functional nanomaterial composed of guanosine monophosphate (GMP) and Fe enhanced denitrification efficiency by regulating electron transfer and microbial community. Fe/GMP enhanced nitrate (NO) degradation rates by 3.00-fold in serum vial batch experiments, with a rate constant of 17.

Effect of Dietary Riboflavin Levels on Reproductive Performance of Pigeon Breeders, and Growth Performance and Carcass Traits of Offspring Squabs.

This study aimed to investigate the effects of dietary riboflavin levels on the reproductive performance of pigeon breeders and the growth performance and carcass traits of offspring squabs to estimate the riboflavin requirement of pigeon breeders. The natural riboflavin content in the basic diet of corn-peas-soybean-wheat-sorghum-corn gluten is 1.20 mg/kg.

Therapeutic targeting of PARP with immunotherapy in acute myeloid leukemia.

Targeting the poly (ADP-ribose) polymerase (PARP) protein has shown therapeutic efficacy in cancers with homologous recombination (HR) deficiency due to BRCA mutations. Only small fraction of acute myeloid leukemia (AML) cells carry BRCA mutations, hence the antitumor efficacy of PARP inhibitors (PARPi) against this malignancy is predicted to be limited; however, recent preclinical studies have demonstrated that PARPi monotherapy has modest efficacy in AML, while in combination with cytotoxic chemotherapy it has remarkable synergistic antitumor effects. Immunotherapy has revolutionized therapeutics in cancer treatment, and PARPi creates an ideal microenvironment for combination therapy with immunomodulatory agents by promoting tumor mutation burden.

Ferroptosis: a potential target for acute lung injury.

Acute lung injury (ALI) is caused by a variety of intrapulmonary and extrapulmonary factors and is associated with high morbidity and mortality. Oxidative stress is an important part of the pathological mechanism of ALI. Ferroptosis is a mode of programmed cell death distinguished from others and characterized by iron-dependent lipid peroxidation.

Rapid prototyping of a retinal multivascular network phantom for optical retinal vascular imaging equipment evaluation.

Retinal vascular health holds paramount importance for healthy vision. Many technologies have been developed to examine retinal vasculature non-destructively, including fundus cameras, optical coherence tomography angiography (OCTA), fluorescein angiography (FA), and so on. However, there is a lack of a proper phantom simulating the critical features of the real human retina to calibrate and evaluate the performance of these technologies.

Percolation thresholds of disks with random nonoverlapping patches on four regular two-dimensional lattices.

In percolation of patchy disks on lattices, each site is occupied by a disk, and neighboring disks are regarded as connected when their patches contact. Clusters of connected disks become larger as the patchy coverage of each disk χ increases. At the percolation threshold χ_{c}, an incipient cluster begins to span the whole lattice.

Wastewater treatment process enhancement based on multi-objective optimization and interpretable machine learning.

Optimization and control of wastewater treatment process (WTP) can contribute to cost reduction and efficiency. A wastewater treatment process multi-objective optimization (WTPMO) framework is proposed in this paper to provide suggestions for decision-making in setting parameters of WTP. Firstly, the prediction models based on Extreme Gradient Boosting (XGB) with Bayesian optimization (BO) are developed for predicting effluent water quality (EQ) and energy consumption (EC) for different influent quality and process parameter settings.

Correlation and polarization singularities of a radially polarized Gaussian Schell-model vortex beam propagating in oceanic turbulence.

The correlation and polarization singularities as the important parameters of a radially polarized Gaussian Schell-model vortex beam propagating in oceanic turbulence have been investigated in detail. On the one hand, the correlation singularity of the beam will first split, and then generate new correlation singularities, and finally vanish in pairs. The longer the propagating distance, the larger the rate of dissipation of mean-square temperature, and the lower initial correlation lengths reduce the stability of correlation singularities.

[Advances of CAR-T cell therapy in treating colorectal cancer].

Globally, colorectal cancer (CRC) ranks as the third most common cancer and the second leading cause of cancer-related fatalities. According to the World Health Organization, there are over 1.9 million annual cases of CRC diagnosed worldwide, resulting in more than 900 000 deaths.