Publications by authors named "Wenli Chang"

Article Synopsis
  • * This study investigates the reasons behind GC resistance in COPD and examines the potential of allyl isothiocyanate (AITC) to help manage this issue by regulating MRP1, which affects the disposition of harmful substances in cells.
  • * Results show that AITC can help remove the toxic compound 4-HNE that damages HDAC2 protein function, making the cells more sensitive to GC treatments again, indicating a promising new approach for managing COPD alongside existing therapies.
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Objective: To summarize the research progress on the mechanism related to traumatic brain injury (TBI) to promote fracture healing, and to provide theoretical basis for clinical treatment of fracture non-union.

Methods: The research literature on TBI to promote fracture healing at home and abroad was reviewed, the role of TBI in fracture healing was summarized from three aspects of nerves, body fluids, and immunity, to explore new ideas for the treatment of fracture non-union.

Results: Numerous studies have shown that fracture healing is faster in patients with fracture combined with TBI than in patients with simple fracture.

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Background: This study was designed to investigate whether intraoperative electrical nerve stimulation has effects on the short-term recovery of cubital tunnel syndrome patients after ulnar nerve release.

Methods: Patients diagnosed as cubital tunnel syndrome were selected. At the same time, they received conventional surgery treatment.

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Objectives: This study aims to quantitatively evaluate the femoral-tibial contact pressure on the knee under certain malrotaional degrees.

Methods: Femoral-tibial contact pressure was carried out on 14 fixed rotational knee models under 200/400/600 N vertical load using ultra-low-pressure sensitive film technology, rotation angles including neutral position (0°, anatomically reduced), 5°, 10°, and 15° internally and externally. Data were collected and analyzed with SPSS software.

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In the present work, the effects of combined enzymatic hydrolysis by cellulase and xylanase (CXEH), fed-batch enzymatic hydrolysis (FBEH) operation and kinetics on production of ferulic acid (FA) and p-coumaric acid (pCA) from pretreated corn straws were investigated. The results showed that CXEH could efficiently increase production of FA and pCA. When performed the FBEH operation by feeding 150 mL enzymatic hydrolysis solution (1.

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Using the first-principle calculations combined with the Boltzmann transport theory, we studied the thermoelectric properties of YCT (T = O, F, OH) MXenes. Specifically, the Seebeck coefficient, thermal and electrical conductivities under constant relaxation time approximation were calculated. Results show that for p-type carriers, YCO has the largest power factor of up to 0.

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BACKGROUND The purpose of this study was to explore the feasibility of ulnar groove plasty guided by a three-dimensional (3D) printing technique for treatment of moderate to severe cubital tunnel syndrome (CuTS) caused by elbow osteoarthritis. MATERIAL AND METHODS Patients with moderate to severe CuTS secondary to osteoarthritis of the elbow were enrolled in our hospital from April 2015 to March 2018. Based on a previously proposed "elbow canal index", a 1: 1 model of the elbow joint was printed using CT image data collected preoperatively.

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Ewing's sarcoma was first reported by J.Ewing in 1921, which is generally originated from soft tissue of the trunk or limbs. Primary Extraskeletal Ewing sarcoma (EES) of pleura is an uncommon condition, which is challenging to diagnose, and rarely reported.

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Dermoid cysts are rare benign tumors that arise from ectopic epiblastic inclusions and account for 0.4% to 1.5% of all tumors.

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Objective: To investigate the effect of residual varus and valgus deformity on the stress distribution of the knee joint after tibial fracture malunion.

Methods: Fourteen adult cadaver specimens were selected to establish the models of tibial fractures, which were fixed subsequently at neutral position (anatomical reduction) and malunion positions (at 5°, 10°, and 15° valgus positions, and 5°, 10°, and 15° varus positions). The stress distribution on the medial and lateral plateau of the tibia was quantitatively measured using ultra-low-pressure sensitive film technology.

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Background: Carcinoma ex pleomorphic adenoma (CXPA) is defined as a malignant salivary gland tumor arising from a primary or recurrent pleomorphic adenoma. Only three cases of CXPA of the trachea have been reported in the literature.

Case Summary: We report a case of tracheal CXPA in a 55-year-old woman, who presented with a more than 3-mo history of progressive dyspnea.

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Background: There has been a lot of research on physical therapy for tension-type headaches. However, the efficacy of physical therapy on the suboccipital region remains unclear.

Objective: To establish the effectiveness of physical therapy on the suboccipital area of patients with tension-type headache.

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Bone, especially cancellous bone, has been demonstrated to be nonhomogeneous. When applied to bone study, it raises the following question: How should the material properties of the bone from the available experimental data be interpolated?In this study, the finite element model of the femur has been built and the nonhomogeneous material properties of the femur have been assigned from the computed tomography (CT) data. These results have been applied to assess some common interpolation algorithms on the bone study, such as Linear Multivariate, Radial Basis, and Nearest Neighbor.

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Background: This randomized controlled trial (RCT) aimed to compare the clinical outcomes of thoracolumbar burst fractures (TLBFs) treated with open reduction and internal fixation via the posterior paraspinal muscle approach (PPMA) and the post-middle approach (PA).

Methods: Patients with a traumatic single-level TLBFs (T10-L2), treated at our hospital between December 2009 and December 2014, were randomly allocated to Group A (PPMA) and Group B (PA). Sex, age, time from injury to surgery, the American Spinal Injury Association Impairment Scale score (ASIAIS), comorbidities, vertebral level, pre- and postoperative kyphotic angle (KA), visual analog scale (VAS) pain score, and the Oswestry Disability Index (ODI) scores were included in the analysis.

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Objective: Although many studies have reported risk factors of mortality following hip fracture surgery, the preventable risk factors of mortality following hip fracture surgery have not been well-identified. The aim of this study was to identify the preventable risk factors of mortality following hip fracture surgery.

Methods: We searched PubMed, Web of Science, Google scholar, and the Chinese National Knowledge Infrastructure (CNKI) databases from January 1997 to March 2017 for studies reporting risk factors of mortality following hip fracture surgery.

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BACKGROUND Clinical studies indicate that in total ankle arthroplasty, postoperative implant subsidence and medial tilt become two significant concerns of the ankle replacement system, and which are associated with the contact between the bones and the talar component. Up to now, little attention has focused on the contact between the bones and the talar component. MATERIAL AND METHODS In order to address implant subsidence and medial tilt, one three-dimensional finite element model of contact between the bone and the talar components was built with the material properties of the cancellous bone interpolated from the experimental data, which represents variation of material properties through the cancellous bones.

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Background: The relative efficacy of operative and nonoperative treatments for the displaced intra-articular calcaneal fractures (DIACF) remains uncertain.

Object: We conducted a meta-analysis to compare the effectiveness of operative and nonoperative treatments in treating patients with DIACF.

Methods: Databases including Cochrane Library, Medline, Embase, CBM, CNKI, and Google Scholar were searched.

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The calcaneus is the most commonly fractured tarsal bone. Displaced intraarticular calcaneal fractures are usually caused by a fall from height with one or both heels directly hitting the ground. Displaced intra-articular calcaneal fractures are complex and highly disabling injuries.

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Background: The debate on the efficacy of unilateral percutaneous kyphoplasty (UPKP) and bilateral percutaneous kyphoplasty (BPKP) for the treatment of osteoporotic vertebral compression fractures (OVCFs) is ongoing.This meta-analysis aimed to evaluate the clinical results of UPKP and BPKP in the treatment of OVCFs.

Methods: Web of Science, PubMed, Embase, and the Chinese Biomedical Database publication databases were searched using a date range of January 2008 to November 2016, for studies comparing UPKP and BPKP for the treatment of OVCFs.

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Background: Implant breakage after the fixation of traumatic fractures is rare; however, when it occurs, it is debilitating for the patients and a challenge for surgeons. The purpose of this study was to analyze and identify the independent risk factors for implant breakage of traumatic fractures treated with plate osteosynthesis.

Methods: We reviewed the medical records of patients with a fracture to any part of their four extremities, clavicle, hand or foot, who underwent surgical plate osteosynthesis from January 2005 to January 2015, and who sustained a subsequent implant breakage.

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Introduction: The debate on efficacy of fusion added to decompression for lumbar spinal stenosis (LSS) is ongoing. No meta-analysis has compared the effectiveness of decompression versus decompression plus fusion in treating patients with LSS.

Methods: A literature search was performed in the Web of Science, PubMed, Embase, and Springer databases from 1970 to 2016.

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