Characterization of the Complete Mitochondrial Genome of Dwarf Form of Purpleback Flying Squid () and Phylogenetic Analysis of the Family Ommastrephidae.

Background: The Ommastrephidae family of cephalopods is important in marine ecosystems as both predators and prey. Species such as , , and are economically valuable but are threatened by overfishing and environmental changes. The genus , especially , shows significant morphological and genetic variation, including medium-sized and dwarf forms found in the South China Sea.

cystatin has protective effects against "two-hit" sepsis in mice by regulating the inflammatory microenvironment.

Objectives: To evaluate the protective effect of cystatin (r-Cystatin) in a mouse mode of "two-hit" sepsis.

Methods: Sixty male C57BL/6 mice randomized equally into sham-operated group, protein group, "two-hit" modeling group, and protein intervention group. In the former two groups, the mice received an intraperitoneal injection of 100 μL PBS followed by exposure of the cecum and then by intraperitoneal injection of 100 μL PBS or 25 μg r-Cystatin 30 min later; In the latter two groups, 100 μL PBS containing LPS (5 mg/kg) was injected intraperitoneally 24 h before cecal ligation and puncture (CLP), and 100 μL PBS or 25 μg r-Cystatin were injected 30 min after CLP.

Proteomic profile of Trichinella spiralis infected mice with acute spinal cord injury: A 4D label-free quantitative analysis.

Spinal cord injury (SCI) can cause severe loss of locomotor and sensory activities, with no ideal treatment. Emerging reports suggest that the helminth therapy is highly effective in relieving numerous inflammatory diseases. Proteomic profiling is often used to elucidate the underlying mechanism behind SCI.