Characterization of polyvinyl alcohol/chitosan nanofibers loaded with royal jelly by blending electrospinning for potential wound dressings.

This study aimed to fabricate a polyvinyl alcohol/chitosan (PVA/CS) nanofiber loaded with royal jelly (RJ) using blending electrospinning for potential wound dressings. The different PVA/CS ratios in electrospun nanofibers resulted in continuous nanofibers with an average diameter ranging from 219 to 299 nm. The FTIR spectra indicated that RJ was successfully incorporated into the nanofibers through hydrogen bonding with PVA/CS, which was further confirmed by the subsequent TGA experiments.

Dispersive Pd islands-deposited Au nanorods for SERS monitoring of catalytic reaction.

In this study, a bifunctional material with SERS effect and catalytic performance is fabricated in which dispersive Pd islands are deposited on the surface of gold nonorods (AuNR@Pd islands) with the confined modification of surface active sites of AuNRs using 5-iodo salicylic acid (5-ISA), which optimize the performance of bifunctional materials.

Emulsion-coaxial electrospinning: The role of zein as a shell layer in multicore-shell structured nanofibers for bioactive delivery.

Multicore-shell nanofibers were fabricated by integrating emulsion electrospinning and coaxial electrospinning technologies, in which the multicore section of the nanofibers was prepared by electrospinning of gelatin-stabilized emulsions, and the shell layer was coaxially electrospun from zein solution. Coaxial electrospinning of zein helped form emulsion-based electrospun fibers with bead-in-string, spindle-like, and straight morphologies. The hydrogen bonding between gelatin and zein contributed to the enhanced thermal properties of coaxially electrospun nanofibers.

miR3398-VqMYB15 Regulates the Synthesis of Stilbene in Vitis quinquangularis.

Grapevine (Vitis vinifera L.) is an economically important fruit crop grown worldwide. Grapevine is cultivated extensively in China, and certain wild grapes exhibit excellent resistance to pathogens and stress.

Machine learning-integrated surface-enhanced Raman spectroscopy analysis of multicomponent dye mixtures.

Surface-enhanced Raman spectroscopy (SERS) is broadly used in the detection and analysis of materials with its fingerprint-like specificity and high sensitivity. However, resembling signals of analytes highly affect the identification and assignment of spectra, which has become a long-term issue to be solved. In this study, various models of machine learning are utilized and compared to support data analysis of complex SERS spectra.

Primary intracranial extraosseous Ewing's sarcoma with intraspinal metastasis in children: illustrative case.

Background: The diagnosis of intracranial extraosseous Ewing's sarcoma (EES) poses challenges due to the absence of specific clinical and imaging features prior to surgery. It is crucial to differentiate the tumor from other small round cell malignancies postoperatively.

Observations: A 7-year-old patient was admitted to the authors' hospital due to the in situ recurrence of a posterior fossa tumor more than 1 month after the initial surgery for headache.

Whole-genome sequencing and genomic analysis of four strains newly isolated from human feces.

Background: Numerous studies have demonstrated that is closely associated with human health. These bacteria colonize the mucus layer of the gastrointestinal tract and utilize mucin as their sole source of carbon and nitrogen. spp.

A neoteric smartphone-assisted colorimetric and fluorometric dual-mode probe based on anthraquinone derived Schiff base for wide-range pH and Cu/S determination in bioimaging.

The fluctuation of ion content has an important effect on human health and ecological environment. Herein, a novel colorimetric and fluorescent dual mode probe (DMHB) has been designed via the imine bond bridging of anthraquinone derivative dye and salicyl hydrazide. The DMHB displays significance wide-range pH dependent spectral behavior (pKa 5.

1α,25(OH)D improves 17β-estradiol secretion and potentially alleviates endoplasmic reticulum stress in muskrat granulosa cells.

Vitamin D plays an essential regulatory role in female reproduction. However, the studies on the correlation between vitamin D and muskrat reproduction are limited. This study aims to determine the role of the active form of vitamin D, 1α,25-dihydroxytamin D [1α,25(OH)D], on muskrat ovarian granulosa cells (MGCs).

Epithelial-mesenchymal transition during the growth and involution of the prostate gland in wild ground squirrels (Spermophilus dauricus).

The prostate glands of wild ground squirrels display enlarged volume during the breeding season and shrunk size during the nonbreeding season, which enables the wild ground squirrel to be an ideal animal model for studying the mechanisms of prostate growth and involution. To clarify the possible mechanism underlying seasonal morphological changes of the prostate in wild ground squirrels, epithelial-mesenchymal transitions (EMT) were focused, and the expression of EMT-related genes was investigated in the current study. Histological results showed that the epithelial lumen enlarged in the breeding season, and the stromal cells expanded during the non-breeding season.

Depression, anxiety and self-esteem in adolescent girls with polycystic ovary syndrome: a systematic review and meta-analysis.

Objective: Studies have shown the adverse psychological impact of polycystic ovary syndrome (PCOS), but the state of mental health in adolescents with PCOS remains unclear. Thus, we performed a systematic review and meta-analysis to investigate the prevalence and severity of depression and anxiety, as well as potential effects on self-esteem and quality of life (QoL) in this specific population.

Methods: We systematically searched four electronic databases: PubMed, Embase, Web of Science, and the Cochrane Reviews database for articles published until 25/8/2024.

SMYD1 modulates the proliferation of multipotent cardiac progenitor cells derived from human pluripotent stem cells during myocardial differentiation through GSK3β/β-catenin&ERK signaling.

Background: The histone-lysine N-methyltransferase SMYD1, which is specific to striated muscle, plays a crucial role in regulating early heart development. Its deficiency has been linked to the occurrence of congenital heart disease. Nevertheless, the precise mechanism by which SMYD1 deficiency contributes to congenital heart disease remains unclear.

Identification of salty peptides from enzymolysis extract of oyster by peptidomics and virtual screening.

Salty peptide as an important sodium substitute, which could reduce the risk of cardiovascular disease caused by excessive sodium intake. In this study, novel salty peptides were prepared and identified from enzymolysis extract of oysters by peptitomic identification, virtual screening and solid phase synthesis. Additionally, molecular simulation was used to study the taste mechanism of salty peptides.

Effects of Different Defatting Methods of Black Soldier Fly () Larvae Meal on the Metabolic Energy and Nutrient Digestibility in Young Laying Hens.

This study aimed to investigate the effects of different defatting methods of black soldier fly () larvae meal (BSFM) on the metabolic energy and nutrient digestibility in laying hens. Sixty young laying hens (Hy-Line W-36) aged 63 days were randomly divided into two groups (G1 and G2), each with five replicates of six hens housed in individual cages. Group G1 was fed 25% pressed black soldier fly meal (BSFMp) and 75% basal diet, and Group G2 was fed 25% extracted black soldier fly meal (BSFMe) and a 75% basal diet.

Double cross-linked chitosan sponge encapsulated with ZrO/soy protein isolate amyloid fibrils nanoparticles for the fluoride ion removal from water.

Fluoride ion pollution in water has become a serious threat to the water environment and human health. Adsorption is a promising means of fluoride removal, but it also faces challenges such as the difficult separation and recovery of powdered particles, the leaching of modified coatings from adsorbents, and the structural disintegration of macroscopic adsorbents. For addressing the above challenges, glutaraldehyde/polyvinyl alcohol co-crosslinked ZrSAF/chitosan spongy composites (ZrS/GPCS) were prepared by utilizing encapsulation strategies and cross-linking.

Up-regulated mitochondrial biogenesis associated with GH/IGF axis in the ovaries of muskrats (Ondatra zibethicus).

Mitochondria play a critical role in follicular development and ovulation, at least in part through the actions of growth hormone (GH)/insulin-like growth factor-1 (IGF-1) on mitochondrial biogenesis. This study aimed to identify seasonal alterations in the GH/IGF-1 system and mitochondrial biogenesis in muskrat (Ondatra zibethicus) ovaries. We utilized the muskrat, a typical seasonal breeder, to clarify the potential impact of the GH/IGF-1 system on mitochondrial biogenesis across different breeding seasons using immunohistochemistry, gene expression and high-throughput sequencing.

Chemistry, bioactivities, structure-activity relationship, biosynthesis and metabolism of prenylated flavonoids in Moraceae plants.

Plants from Moraceae are globally popular as they represent a valuable resource with wide applications in food, health-care products, and other fields. Prenylated flavonoids are important active components in Moraceae. These compounds share a flavonoid skeleton with prenylated side chain, mostly in the form of single or multiple isoprenyl substituents and benzodimethylfuran structures.

A turn-on anthraquinone-derived colorimetric and fluorometric dual-mode probe for highly selective Hg determination and bioimaging in living organisms.

Mercury ion (Hg) is considered a harmful neurotoxin, and real-time monitoring of Hg concentrations in environmental and biological samples is critical. Fluorescent probes are a rapidly emerging visualization tool owing to their simple design and good selectivity. Herein, a novel fluorescence (FL) probe 2-(4-((6-((quinolin-8-yloxy)methyl)pyridin-2-yl)methyl)piperazin-1-yl)anthracene-9,10-dione (QPPA) is designed using piperazine as a linker between the anthraquinone group, which serves as a fluorophore, and NO as the Hg ligand.

Encapsulation of lycopene in Pickering emulsion stabilized by complexes of whey protein isolate fibrils and sodium alginate: Physicochemical property, structural characterization and in vitro digestion property.

In present study, whey protein isolate fibrils and sodium alginate complexes (WPIFs-SA) were prepared and further used to stabilize Pickering emulsions for lycopene delivery. The optimal interaction between WPIFs and SA occurred at pH 3.0, with a mass ratio of 2:1.

Development of a nomogram for predicting liver transplantation prognosis in hepatocellular carcinoma.

Background: At present, liver transplantation (LT) is one of the best treatments for hepatocellular carcinoma (HCC). Accurately predicting the survival status after LT can significantly improve the survival rate after LT, and ensure the best way to make rational use of liver organs.

Aim: To develop a model for predicting prognosis after LT in patients with HCC.