PD-like pathogenesis induced by intestinal exposure to microplastics: An in vivo study of animal models to a public health survey.

With the increasing incidence of non-hereditary Parkinson's disease (PD), research into the involvement of specific environmental factors, in addition to aging, has become more prominent. The effects of microplastic exposure on public health have gained increased attention as it is known to cause a range of neurotoxic changes, some of which are similar to the pathological features of PD. We carried out low-dose microplastic exposure experiments on mice and Caenorhabditis elegans models and implemented a survey regarding the utilization of plastic products in the population.

Safety and Efficacy of Percutaneous Drain Placement for Postsurgical Breast Region Fluid Collections.

Objective: The purpose of this study was to describe the safety and efficacy of percutaneous drain placement for postoperative fluid collections in the breast.

Methods: A retrospective review was conducted of the patient characteristics, intervention data, and clinical outcomes of the 43 adult patients who underwent percutaneous drain placement for fluid collections at a tertiary care hospital over a 13-year period ending February 28, 2023.

Results: Most fluid collections treated with percutaneous drain placement were secondary to ipsilateral breast surgery (92%, 44/48), most commonly breast reduction (23%, 10/44) and mastectomy with immediate tissue expander reconstruction (16%, 7/44).

Bioluminescent Probes for the Detection of Superoxide and Nitric Oxide.

The regulation of reactive oxygen species (ROS) such as superoxide (SO) and nitric oxide (NO) is crucial in biology, influencing metabolism and signaling pathways. Imbalances in these species lead to oxidative stress and various diseases. Traditional methods for measuring SO and NO face challenges in terms of sensitivity and specificity, particularly in complex biological matrices.

Corrigendum: The impact of Chinese COVID-19 pandemic on the incidence of peripheral facial nerve paralysis after optimizing policies.

[This corrects the article DOI: 10.3389/fpubh.2023.

CT-guided microwave ablation of renal cell carcinoma in a horseshoe kidney.

Renal fusion anomalies are rare congenital malformations that comprise horseshoe kidney and crossed fused ectopia. Renal tumors arising from these fusion anomalies are anatomically complex, and surgical management can be technically challenging because of altered renal anatomy. Percutaneous CT-guided ablation can overcome some of these anatomical constraints, and microwave ablation has the additional benefit of shorter treatment time and reduced sensitivity to heat sink effects compared to other ablative modalities.

Hydrophobic modification and durability protection of cotton garment fabric surfaces by graphene oxide/PGMA composite coatings.

Cotton fiber fabric with practicability and functionality attracts much attention and plays an important role in many occasions. However, its surface contains many hydroxyl groups to show a hydrophilicity, leading to easy adhesion to stains to limit the application. In this work, polyglycidyl methacrylate (PGMA) was used as an oily and flexible matrix and graphene oxide (GO) particles were used as a filler.

Exploring biomarkers of Alzheimer's disease based on multi-omics and Mendelian randomisation analysis.

Background: Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with no fully curative treatment.

Aim: This study aims to identify effective biomarkers for AD diagnosis and treatment by combining multi-omics and Mendelian randomisation (MR) analyses.

Subjects And Methods: Positron emission tomography (PET), single nucleotide polymorphism (SNP), and gene expression data of AD patients using advanced correlation analysis methods (AdaSMCCA, rAdaSMCCA, and unAdaSMCCA algorithms) are integrated.

Visible-Light-Driven Oxidation of Benzene to Phenol with O over Photoinduced Oxygen-Vacancy-Rich WO.

Direct photocatalytic conversion of benzene to phenol with molecular oxygen (O) is a green alternative to the traditional synthesis. The key is to find an effective photocatalyst to do the trick. Defect engineering of semiconductors with oxygen vacancies (OVs) is an emerging strategy for catalyst fabrication.

Accumulation of nanoplastics by wheat seedling roots: Both passive and energy-consuming processes.

Nanoplastics can transfer from the environment to plants and potentially harm organisms. However, the mechanisms on how crop root systems absorb and transport nanoplastics are still unclear. Here, original and fluorescent labeled polystyrene and polyvinyl chloride nanoparticles (PS-NPs, PVC-NPs; 30 nm; 10 mg L) were employed to study the distribution and internalization pathways in wheat seedling roots.

The influence of occupational noise exposure on blood pressure and hearing loss among female workers of childbearing age.

Objectives: Women exposed to occupational noise experience adverse pregnancy outcomes. Therefore, we initiated a large, population-based, cross-sectional study to further investigate the effects of occupational noise on hearing and blood pressure among female workers of childbearing age.

Study Design And Setting: A total of 6981 childbearing-aged female workers were selected for this cross-sectional study.

Identification of NanoLuciferase Substrates Transported by Human ABCB1 and ABCG2 and Their Zebrafish Homologs at the Blood-Brain Barrier.

ATP-binding cassette (ABC) transporters expressed at the blood-brain barrier (BBB) impede delivery of therapeutic agents to the brain, including agents to treat neurodegenerative diseases and primary and metastatic brain cancers. Two transporters, ABCB1 and ABCG2, are highly expressed at the BBB and are responsible for the efflux of numerous clinically useful chemotherapeutic agents, including irinotecan, paclitaxel, and doxorubicin. Based on a previous mouse model, we have generated transgenic zebrafish in which expression of NanoLuciferase (NanoLuc) is controlled by the promoter of glial fibrillary acidic protein, leading to expression in zebrafish glia.

Research on Non-Destructive Quality Detection of Sunflower Seeds Based on Terahertz Imaging Technology.

The variety and content of high-quality proteins in sunflower seeds are higher than those in other cereals. However, sunflower seeds can suffer from abnormalities, such as breakage and deformity, during planting and harvesting, which hinder the development of the sunflower seed industry. Traditional methods such as manual sensory and machine sorting are highly subjective and cannot detect the internal characteristics of sunflower seeds.

PRL1 interacts with and stabilizes RPA2A to regulate carbon deprivation-induced senescence in Arabidopsis.

Leaf senescence is a developmental program regulated by both endogenous and environmental cues. Abiotic stresses such as nutrient deprivation can induce premature leaf senescence, which profoundly impacts plant growth and crop yield. However, the molecular mechanisms underlying stress-induced senescence are not fully understood.

Intergenerational epigenetic inheritance mediated by MYS-2/MOF in the pathogenesis of Alzheimer's disease.

Although autosomal-dominant inheritance is believed an important cause of familial clustering Alzheimer's disease (FAD), it covers only a small proportion of FAD incidence, and so we investigated epigenetic memory as an alternative mechanism to contribute for intergenerational AD pathogenesis. Our data showed that mys-2 of that encodes a putative MYST acetyltransferase responsible for H4K16 acetylation modulated AD occurrence. The phenotypic improvements in the parent generation caused by mys-2 disfunction were passed to their progeny due to epigenetic memory, which resulted in similar H4K16ac levels among the candidate target genes of MYS-2 and similar gene expression patterns of the AD-related pathways.

Robot-assisted, laparoscopic and open radical cystectomy for bladder cancer: A systematic review and network meta-analysis.

Objectives: To evaluate the safety and effectiveness of robot-assisted radical cystectomy (RARC), laparoscopic radical cystectomy (LRC), and open radical cystectomy (ORC) in bladder cancer.

Methods: A literature search for network meta-analysis was conducted using international databases up to February 29, 2024. Outcomes of interest included baseline characteristics, perioperative outcomes and oncological outcomes.

Estrogen Receptor-targeted PET Imaging for Breast Cancer.

Two complementary patient cases are presented to highlight the importance of estrogen receptor (ER)-targeting imaging in treatment planning and selection for endocrine therapy in breast cancer patients. This article will discuss the radiopharmaceuticals and biology, imaging interpretation, and current clinical applications of ER-targeting imaging using fluorine 18 fluoroestradiol PET.

Synergistic Crystallization Modulation and Defects Passivation in Kesterite via Anion-Coordinate Precursor Engineering for Efficient Solar Cells.

It has been validated that enhancing crystallinity and passivating the deep-level defect are critical for improving the device performance of kesterite CuZnSn(S,Se) (CZTSSe) solar cells. Coordination chemistry interactions within the Cu-Zn-Sn-S precursor solution play a crucial role in the management of structural defects and the crystallization kinetics of CZTSSe thin films. Therefore, regulating the coordination environment of anion and cation in the precursor solution to control the formation process of precursor films is a major challenge at present.

Outcomes Analysis of Yttrium-90 Radioembolization for Tumors Other Than Metastatic Colorectal Cancer from the Radiation-Emitting SIR-Spheres in Nonresectable (RESiN) Registry.

Purpose: To characterize the response and survival outcomes of yttrium-90 (Y) transarterial radioembolization (TARE) for unresectable, liver-dominant metastases from primary neoplasms other than colorectal carcinoma.

Materials And Methods: This study included 1,474 patients enrolled in the Radiation-Emitting Society of Interventional Radiology (SIR)-Spheres in Nonresectable Liver Tumor registry who received resin Y-TARE as part of their oncologic management for unresectable primary or secondary liver tumors (NCT02685631). Of these patients, 33% (481/1,474) were treated for liver metastases of noncolorectal origin (m-non-CRC) compared with 34% (497/1,474) treated for metastatic colorectal cancer (mCRC) and 34% (496/1,474) treated for hepatocellular carcinoma.

Indole-3-acetic acid enhances the co-transport of proton and phenanthrene mediated by TaSAUR80-5A in wheat roots.

Polycyclic aromatic hydrocarbons (PAHs) are a type of organic pollution that can accumulate in crops and hazard human health. This study used phenanthrene (PHE) as a model PAH and employed hydroponic experiments to illustrate the role of indole-3-acetic acid (IAA) in the regulation of PHE accumulation in wheat roots. At optimal concentrations, wheat roots treated with PHE + IAA showed a 46.

Effects of high-normal fasting blood glucose on ART outcomes of frozen-thawed single blastocyst transfer in women with normal BMI.

Purpose: This retrospective cohort study aims to investigate whether high-normal fasting blood glucose (FBG) affects assisted reproductive technology (ART) outcomes undergoing single blastocyst frozen-thawed embryo transfer (FET) cycles in women with normal body mass index (BMI).

Methods: 944 women with normal BMI and FBG levels undergoing single blastocyst FET cycles were enrolled. Based on the median of FBG (4.

Temporal-spatial cross attention network for recognizing imagined characters.

Previous research has primarily employed deep learning models such as Convolutional Neural Networks (CNNs), and Recurrent Neural Networks (RNNs) for decoding imagined character signals. These approaches have treated the temporal and spatial features of the signals in a sequential, parallel, or single-feature manner. However, there has been limited research on the cross-relationships between temporal and spatial features, despite the inherent association between channels and sampling points in Brain-Computer Interface (BCI) signal acquisition, which holds significant information about brain activity.