KIF20A activated by transcription factor GATA2 promotes cell growth in hepatitis B virus-related hepatocellular carcinoma.

Background: Elevated evidence suggests that KIF20A plays an important role in hepatocellular carcinoma (HCC) progression. Nevertheless, the underlying mechanism by which KIF20A promotes HCC cell growth are not well understood.

Methods: Using TCGA-LIHC RNAseq and GEO datasets, we assessed the KIF20A expression and patient survival in HCC and hepatitis B virus (HBV)-related HCC.

Restraining Planar Gliding in Single-Crystalline LiNiCoMnO Cathodes by Combining Bulk and Surface Modification Strategies.

The delamination cracking from planar gliding along the (003) facets and anisotropic lattice strain perpendicular to the (003) facets inevitable lead to degradation of Ni-rich single-crystal cathode materials, adversely affecting their cyclability. Herein, we rationally design a single-crystal LiNiCoMnO (SC90) cathode with robust chemo-mechanical properties, in which coherently grown MgO octahedra and BO tetrahedra are incorporated into the lattice, and a stabilizing Mg(BO) layer is concurrently formed on the particle surface. Multiscale in/ex situ characterizations and theoretical calculations indicate that introducing the MgO and BO units leads to a "pinning effect" within the layered structure.

Archipelago-like oxygen-vacancies-enriched amorphous-crystalline heterointerface for enhanced water splitting.

Advancing the development of proficient bifunctional water splitting electrocatalysts and deciphering the underlying drivers of their performance are pivotal for accelerating the sustainable hydrogen energy sector. In this study, a novel Fe and P dual-doped cobalt molybdate electrocatalyst (P-FCMO@NF) is engineered in-situ on a nickel foam substrate that induces an archipelago-like amorphous-crystalline heterointerface as well as abundant oxygen vacancies (V) on the near-surface, in favor of the electron transport and enhancing the water splitting capability respectively. Consequently, P-FCMO@NF exhibits excellent electrocatalytic performance in 1 M KOH solution.

Oxygen vacancies enhanced electrocatalytic water splitting of P-FeMoO initiated via phosphorus doping.

Transition metal oxides (TMOs) are abundant and cost-effective materials. However, poor conductivity and low intrinsic activity limit their application in electrolyzed water catalysts. Herein, we prepared P-FeMoO in situ on nickel foam (P-FMO@NF) by phosphorylation-modified FeMoO to optimize its electrocatalytic properties.

Temperature, pressure, and humidity SAW sensor based on coplanar integrated LGS.

This paper presents a surface acoustic wave (SAW) sensor based on coplanar integrated Langasite (LGS) that is fabricated using wet etching, high-temperature bonding, and ion beam etching (IBE) processes. The miniaturized multiparameter temperature‒pressure-humidity (TPH) sensor used the MXene@MoS@Go (MMG) composite to widen the humidity detection range and improve the humidity sensitivity, including a fast response time (3.18 s) and recovery time (0.

Effectiveness of Fuling () and its extracts against spleen deficiency in rats tonifying spleen.

Objective: To observe and explore the effect of Fuling () in alleviating the spleen deficiency symptom pattern (SDSP).

Methods: We established an animal model of SDS in Sprague-Dawley () rats by treating them with deficiency-inducing factors, including irregular feeding and tail clamping. Mice were administered Fuling () and its extracts (raw/cooked powder, aqueous/alcohol extract) by gavage once a day for 21 d.

Surface-Diluted LiMn Superstructure Units Utilizing PO Confined Ni-Doping Sites to Stabilize Li-Rich Layered Oxides.

Serious capacity and voltage degradation of Li-rich layered oxides (LLOs) caused by severe interfacial side reactions (ISR), structural instability, and transition metal (TM) dissolution during charge/discharge need to be urgently resolved. Here, it is proposed for the inaugural time that the confinement effect of PO dilutes the LiMn superstructure units on the surface of LLOs, while deriving a stable interface with phosphate compounds and spinel species. Combining theoretical calculations, diffraction, spectroscopy, and micrography, an in-depth investigation of the mechanism is performed.

lncRNA TPT1-AS1 promotes cell migration and invasion in esophageal squamous-cell carcinomas by regulating the miR-26a/HMGA1 axis.

lncRNA TPT1-AS1 plays an oncogenic role in ovarian and cervical cancers. However, its involvement in the pathological progress of esophageal squamous-cell carcinomas (ESCCs) is unclear. lncRNA TPT1-AS1 was mainly localized in the cytoplasm of ESCC cells and interacted with miR-26a.

P-Doped Cotton Stalk Carbon for High-Performance Lithium-Ion Batteries and Lithium-Sulfur Batteries.

Biomass as a carbon material source is the characteristic of green chemistry. Herein, a series of hierarchical P-doped cotton stalk carbon materials (HPCSCMs) were prepared from cheap and abundant biowaste cotton stalk. These materials possess a surface area of 3463.

FeO/MoO@NG Heterostructure Enables High Pseudocapacitance and Fast Electrochemical Reaction Kinetics for Lithium-Ion Batteries.

Transition metal oxides (TMOs) hold great potential for lithium-ion batteries (LIBs) on account of the high theoretical capacity. Unfortunately, the unfavorable volume expansion and low intrinsic electronic conductivity of TMOs lead to irreversible structural degradation, disordered particle agglomeration, and sluggish electrochemical reaction kinetics, which result in perishing rate capability and long-term stability. This work reports an FeO/MoO@NG heterostructure composite for LIBs through the uniform growth of FeO/MoO heterostructure quantum dots (HQDs) on the N-doped rGO (NG).

Anti-Fogging, Frost-Resistant transparent and flexible silver Nanowire-TiCT MXene based composite films for excellent electromagnetic interference shielding ability.

The development of electronics proposes higher requirements for flexible, transparent, and conductive materials with high electromagnetic shielding performance in viewing windows. Flexible transparent films have been fabricated by collaborating one-dimensional silver nanowires (AgNWs) and novel two-dimensional TiCT MXene sheets on PET films with an external polymeric coating consisting of poly (vinyl alcohol) (PVA) and poly(styrene sulfonate) (PSS). Especially, the combination of different dimensional nanomaterials effectively establishes a conductive network that exhibits a synergistic effect on excellent electromagnetic interference (EMI) shielding performance, which is superior to that of pure AgNW network or TiCT network to some extent.

EBSD Characterization of the Microstructure of 7A52 Aluminum Alloy Joints Welded by Friction Stir Welding.

The microstructure and texture of materials significantly influence the mechanical properties and fracture behavior; the effect of microstructure in different zones of friction stir-welded joints of 7A52 aluminum alloy on fracture behavior was investigated in this paper. The microstructural characteristics of sections of the welded joints were tested using the electron backscattered diffraction (EBSD) technique. The results indicate that the fracture is located at the advancing side of the thermomechanically affected zone (AS-TMAZ) and the stir zone (SZ) interface.

Space Detumbling Robot Arm Deployment Path Planning Based on Bi-FMT* Algorithm.

In order to avoid damage to service satellites and targets during space missions and improve safety and reliability, it is necessary to study how to eliminate or reduce the rotation of targets. This paper focused on a space detumbling robot and studied the space detumbling robot dynamics and robot arm deployment path planning. Firstly, a certain space detumbling robot with a 'platform + manipulator + end effector' configuration is proposed.

Functionalizing TiCT for enhancing fire resistance and reducing toxic gases of flexible polyurethane foam composites with reinforced mechanical properties.

Flexible polyurethane foam (FPUF) is the most used polyurethane, but the highly flammable characteristic limits its widespread usage. In this work, ZIF-8@TiCTwas synthesized to reduce the heat and toxic gases of FPUF. Flame-retardant FPUF was characterized by cone calorimeter (Cone), thermogravimetric analysis/fourier-transform infrared spectroscopy (TG-FTIR), tensileand compression tests.

A facile strategy for lightweight, anti-dripping, flexible polyurethane foam with low smoke emission tendency and superior electromagnetic wave blocking.

Flexible polyurethane foam (FPUF) has been considered as an excellent material in many fields, such as furniture and electromagnetic interference (EMI) shielding products due to its lightweight and flexibility. However, there is a severe fire hazard problem for FPUF that makes it unsuitable to be used in practical. Herein, a facile method was to prepare anti-dripping FPUF via electroless plating at ambient temperature.

Durable electromagnetic interference (EMI) shielding ramie fabric with excellent flame retardancy and Self-healing performance.

Although more and more attention has been paid to electromagnetic interference (EMI) shielding fabric materials due to increasing electromagnetic waves pollution, little attention to their fire safety behavior and durability in practical use. Herein, durable EMI shielding ramie fabric with flame retardant and self-healing performance were fabricated by depositing ammonium polyphosphate (APP)/polyethyleneimine (PEI) layer, MXene sheets and polycaprolactone (PCL) layer. The resultant multifunctional fabric could self-extinguish and the peak heat release rate (pHRR) value reduced about 74.

Saccharin Anion Acts as a "Traffic Assistant" of Zn to Achieve a Long-Life and Dendritic-Free Zinc Plate Anode.

Due to the great advantages of low cost, high capacity, and excellent safety, the Zn metal is a promising candidate material for rechargeable aqueous battery systems. However, its practical applications have been restricted by the uncontrollable dendrite growth and electrode side reactions (such as corrosion, passivation, and hydrogen evolution reactions) during the plating process. Herein, we reveal that the dendrite growth would expose the electrode to more highly active tips, exacerbating the passivation of the electrode and the decomposition of the electrolyte by in situ optical microscopies.

Oxygen Vacancy Enhanced Two-Dimensional Lithium Titanate for Ultrafast and Long-Life Bifunctional Lithium Storage.

Boosting sufficient Li ion mobility in LiTiO (LTO) is crucial for high-rate performance lithium storage. Here, an ultrafast charge storage oxygen vacancy two-dimensional (2D) LTO nanosheet was successfully fabricated through a one-pot hydrothermal method. The selectively doped Al into octahedron Li/Ti 16d sites not only provide bulk oxygen vacancy and appropriate distorted TiO octahedra to facilitate Li ions diffusion, but also serve as a "pillar" to stabilize the Ti-O framework.

Self-healable castor oil-based waterborne polyurethane/MXene film with outstanding electromagnetic interference shielding effectiveness and excellent shape memory performance.

Recently, the increasing demands of the portable devices and flexible electronics have caused lots of electromagnetic wave pollution. MXene, a novel two-dimensional material, was considered as a promising two-dimensional material for preparing flexible electromagnetic interference (EMI) shielding films. Herein, we firstly synthesized a series of flexible and self-healable EMI shielding waterborne polyurethane (ADWPU) films by mechanically blending with TiCT (ADWPU-T).

Nacre-Inspired Tunable Electromagnetic Interference Shielding Sandwich Films with Superior Mechanical and Fire-Resistant Protective Performance.

With the rapidly increasing development of portable device hardware and flexible electronics, ultrathin electromagnetic interference (EMI) shielding films with a combination of high flexibility and excellent mechanical properties are noticeably required. In addition to minimizing the electromagnetic wave pollution problem, the fire hazards caused by accidental electrical leakage or aging are also a cause of extensive concern. Inspired by nacre and sandwich structure, herein, we fabricated for the first time an electrical insulating sandwich-structured film based on Ca ion cross-linked sodium alginate (SA)-montmorillonite (MMT) and TiCT MXene through a step-by-step vacuum-assisted filtration process.

Antimicrobial colloidal hydrogels assembled by graphene oxide and thermo-sensitive nanogels for cell encapsulation.

Hydrogels are promising 3D materials that have demonstrated increasing applications in the encapsulation and delivery of drugs and cells. Herein we report an injectable colloidal hydrogel that directly assembled by graphene oxide (GO) and thermo-sensitive nanogels (tNG). The pH dependent hydrogen bonding interactions between the carboxyl and oxethyl groups induce the reversible assembly of GO and nanogels.

High internal phase emulsions stabilised by supramolecular cellulose nanocrystals and their application as cell-adhesive macroporous hydrogel monoliths.

Nanosized celluloses are attractive building blocks to generate hierarchically advanced materials and have been gradually explored in emulsion applications. Here we report a high internal phase emulsion (HIPE) prepared by using supramolecular cellulose nanocrystals (CNCs) as Pickering stabilisers via one-step emulsification, and interconnected macroporous hybrid hydrogels were produced by utilizing this HIPE as a template. A quadruple hydrogen bonding moiety 2-ureido-4[1H]-pyrimidone (UPy) was firstly grafted onto the surface of cellulose nanocrystals through simple free radical polymerization.

[Jatropha seed oils extracted by different methods and their effect on killing cercaria of Schistosoma japonicum].

Objective: To evaluate the effect of Jatropha seed oils extracted by different methods on killing cercaria of Schistosomajaponicum so as to screen the optimum process and formulations.

Methods: The cercaria directly contacting tests with Jatropha seed oils extracted by 6 different extraction processes were carried out, and the mouse immediate contacting cercaria infection trials with different formulations of Jatropha seed oil and various additives were performed.

Results: With 95% ethanol, the ratio of material to liquid being 1:8, and 2 h extraction, the oil extraction rate was 30.

WinHAP: an efficient haplotype phasing algorithm based on scalable sliding windows.

Haplotype phasing represents an essential step in studying the association of genomic polymorphisms with complex genetic diseases, and in determining targets for drug designing. In recent years, huge amounts of genotype data are produced from the rapidly evolving high-throughput sequencing technologies, and the data volume challenges the community with more efficient haplotype phasing algorithms, in the senses of both running time and overall accuracy. 2SNP is one of the fastest haplotype phasing algorithms with comparable low error rates with the other algorithms.