Inversion of winter wheat leaf area index from UAV multispectral images: classical vs. deep learning approaches.

Precise and timely leaf area index (LAI) estimation for winter wheat is crucial for precision agriculture. The emergence of high-resolution unmanned aerial vehicle (UAV) data and machine learning techniques offers a revolutionary approach for fine-scale estimation of wheat LAI at the low cost. While machine learning has proven valuable for LAI estimation, there are still model limitations and variations that impede accurate and efficient LAI inversion.

LDC7559 inhibits microglial activation and GSDMD-dependent pyroptosis after subarachnoid hemorrhage.

Mounting evidence indicates that inhibition of microglial activation and neuronal pyroptosis plays important roles in brain function recovery after subarachnoid hemorrhage (SAH). LDC7559 is a newly discovered gasdermin D (GSDMD) inhibitor. Previous studies have demonstrated that LDC7559 could inhibit microglial proliferation and pyroptosis.

Enhancing adoptive T cell therapy for solid tumor with cell-surface anchored immune checkpoint inhibitor nanogels.

The efficacy of Adoptive Cell Therapy (ACT) for solid tumor is still mediocre. This is mainly because tumor cells can hijack ACT T cells' immune checkpoint pathways to exert immunosuppression in the tumor microenvironment. Immune Checkpoint Inhibitors such as anti-PD-1 (aPD1) can counter the immunosuppression, but the synergizing effects of aPD1 to ACT was still not satisfactory.

Fabrication and characterization of impact-resistant core-spun yarn fabrics with a hydroxylated fullerene-strengthened shear thickening fluid.

Shear thickening fluid (STF) is investigated to strength soft armor; however, its impact resistance still does not meet practical needs. In this work, a small amount of hydroxylated fullerene (C) was mixed with STF to improve the thickening ratio. First, furfuryl alcohol (FA) was grafted onto C through a Diels-Alder (D-A) reaction to improve the dispersity of C in the STF.

Preliminary study of the consciousness-promotion mechanism of electroacupuncture in comatose patients with diffuse axonal injuries.

Background: Diffuse axonal injury (DAI) accounts for 30-40% of total neurotrauma cases, and the majority among them manifest with consciousness disturbance. At present, the understanding of the treatment of coma and awakening in patients with DAIs is still limited. This study is characterized by the use of electroacupuncture along with conventional Western medicine to promote consciousness more effectively in comatose patients with DAIs, shorten their time spent in a coma, and gain time for more favorable treatments during follow-up rehabilitation in order to improve the cure rate, reduce the morbidity rate, and achieve better therapeutic effects.