Publications by authors named "Wenhe Kuai"
Article Synopsis
- * Out of the samples, 1,788 tested positive for NoV, with the highest incidence in children aged 0-2 years and peaks occurring in the winter and spring seasons.
- * Notable findings included the dominance of the GII genotype with variants changing approximately every two years, where GII.4 strains were the most common, especially in children, and GII.17 was mainly found in adults.
Brucellosis is among the key zoonotic infectious diseases in China, and The Ningxia Hui Autonomous Region represents a major endemic area, and it is one of the main causes of poverty in the region due to illness. In Ningxia, there is substantial research on Brucella melitensis, studies on the molecular epidemiology of Brucella abortus are notably scarce. Consequently, this study aims to undertake pathogenic isolation and molecular epidemiological research on Brucella abortus isolated from the environment in Ningxia, providing insights and evidence to advance the prevention and control measures for brucellosis in the region.
View Article and Find Full Text PDFWe tested HIV-infected people with HBV serological markers of Ningxia. Of 1008 HIV-positive individuals, 70 (6.9 %) tested positive for HBsAg, 570 (56.
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- The incidence of anthrax in the Ningxia Hui Autonomous Region has significantly increased since 2019, affecting public health and the economy, which prompted a molecular study of 20 anthrax strains from 2019-2023 to investigate their origins and genetic diversity.
- The study used techniques like CanSNPs typing and whole genome sequencing to analyze genomic characteristics and performed phylogenetic studies to understand the relationships among the strains.
- Results indicated that the dominant strain in Ningxia was A.Br.001/002, and it showed genetic similarities with strains from Europe, Indonesia, and Georgia (USA), suggesting historical links through ancient trade routes.
Genomic analysis of two rare human G3P[9] rotavirus strains in Ningxia, China.
Infect Genet Evol
December 2023
Article Synopsis
- G3P rotaviruses have a unique genetic makeup and complex evolution, yet they have been under-researched, limiting understanding of rotavirus diversity.
- Recent studies identified two new G3P strains in Chinese diarrhea patients, showing a previously unreported genetic constellation in China, which closely relates to feline and bovine rotavirus strains.
- Phylogenetic analysis indicates that the G3P strains from Ningxia originated from reassortment among various rotaviruses, suggesting a complex evolutionary history with ties to both human and animal strains.
Article Synopsis
- * It also highlights the emergence of GII.6[P7] as a significant non-GII.4 strain, predominantly identified from May to July 2020, with researchers sequencing and analyzing the whole genomes of specific strains collected during that time.
- * Phylogenetic analysis indicated that the GII.6 [P7] strains PL20-044 and QTX20-071 have undergone intra
Background: Group A rotaviruses (RVA) are the primary pathogens of acute gastroenteritis. Currently, two live attenuated RVA vaccines, LLR and RotaTeq, have been introduced into mainland China but are not included in the national immunization program. Because of the unknown genetic evolution of group A rotavirus in an all-age population in Ningxia, China, we monitored the epidemiological characteristics and circulating genotypes of RVA as a reference for developing vaccine strategies.
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