Publications by authors named "Wenge Tang"

() is a pathogen of significant concern in food due to its ability to survive and multiply under harsh environmental conditions, such as high osmotic pressure, low temperatures, and freezing. This bacterium can cause listeriosis, a severe infection particularly dangerous for high-risk groups including newborns, pregnant women, and immunocompromised patients, due to its high morbidity and mortality rates. This study aimed to investigate the molecular epidemiological characteristics of isolated in Chongqing, southwest China.

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Background: Capsaicin is the main component of chili peppers and is believed to have antidiabetic effects. However, the association between spicy food consumption and the incidence of diabetes remains unclear.

Methods: A cohort of 20,490 Han residents aged 30-79 without diabetes at baseline were followed from enrollment to June 2, 2023.

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Article Synopsis
  • * A population-based study from October 2021 to March 2022 involved active surveillance, sampling, and health surveys to estimate the disease burden, revealing approximately 52,960 ARI cases, including 2,529 severe ARI (SARI) cases.
  • * The findings showed higher incidence rates of ARI in those under 50 years and SARI in those 50 and older, underlining the importance of vaccination and informing health policy decisions.
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  • A study in Chongqing, Southwest China, explored changes in scarlet fever incidence from 2005 to 2023, noting a focus on predicting cases in 2024 and 2025 amidst the impact of the COVID-19 pandemic.
  • Research showed a total of 9,593 reported cases, with children aged 3-7, particularly 6-year-olds, being the most affected group; the incidence was notably higher in boys and peaked seasonally in spring and late fall.
  • Spatial analysis indicated scarlet fever outbreaks were concentrated in urban areas, with a significant rise in cases after COVID restrictions, showing a 106.54% increase in incidence from 2015-2019 and fluctuating decreases during the
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Article Synopsis
  • Influenza vaccination is a cost-effective method for preventing influenza, showing positive outcomes for symptomatic cases and outpatient illnesses.
  • A study in Chongqing, China, analyzed data from over 15,000 individuals with influenza-like illnesses, revealing an overall vaccine effectiveness (IVE) of 44.4% between 2018 and 2022.
  • The effectiveness varied by age group, with higher effectiveness in adolescents (48.2%) and adults (72.0%), while specific strains like H1N1 showed a notable IVE of 71.1%, indicating the need for ongoing evaluations of vaccine effectiveness annually.
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Objective: To prospectively investigate the associations of healthy lifestyle factors on the risk of stroke and stroke subtypes, as studies exploring this relationship are limited in China.

Methods: The 22,661 participants in the prospective cohort study in Chongqing, China, aged 30-79 years and stroke-free at baseline completed follow-up from 2018 to 2022. We included seven healthy lifestyle factors, including non-smoking, non-excessive drinking, sufficient physical activity, healthy diet, sleep duration of 7-9 h/d, and standard range of body mass index and waist-to-hip ratio.

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Dengue fever is a viral illness, mainly transmitted by Aedes aegypti and Aedes albopictus. With climate change and urbanisation, more urbanised areas are becoming suitable for the survival and reproduction of dengue vector, consequently are becoming suitable for dengue transmission in China. Chongqing, a metropolis in southwestern China, has recently been hit by imported and local dengue fever, experiencing its first local outbreak in 2019.

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Background: To assess the immunogenicity of the current primary polio vaccination schedule in China and compare it with alternative schedules using Sabin or Salk-strain IPV (sIPV, wIPV).

Methods: A cross-sectional investigation was conducted at four sites in Chongqing, China, healthy infants aged 60-89 days were conveniently recruited and divided into four groups according to their received primary polio vaccination schedules (2sIPV + bOPV, 2wIPV + bOPV, 3sIPV, and 3wIPV). The sero-protection and neutralizing antibody titers against poliovirus serotypes (type 1, 2, and 3) were compared after the last dose.

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The temporal relationship between non-alcoholic fatty liver disease (NAFLD) and hypertension remains highly controversial, with ongoing debates on whether NAFLD induces hypertension or vice versa. We employed cross-lagged panel models to investigate the temporal relationship between hepatic steatosis (assessed by Fatty Liver Index [FLI] in the main analysis, and by Proton Density Fat Fraction [PDFF] in the validation study) and blood pressure (systolic and diastolic blood pressure [SBP/ DBP]). Subsequently, we employed causal mediation models to explore the mediation effect in CVD development, including ischemic heart disease and stroke.

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Background: Although exposure to greenness has generally benefited human metabolic health, the association between greenness exposure and metabolic obesity remains poorly studied. We aimed to investigate the associations between residential greenness and obesity phenotypes and the mediation effects of air pollutants and physical activity (PA) level on the associations.

Methods: We used the baseline of the China Multi-Ethnic Cohort (CMEC) study, which enrolled 87,613 adults.

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Objectives: This study aimed to assess the healthcare-seeking behaviour and related factors of people with acute respiratory symptoms in the rural areas of central and western China to estimate the disease burden of influenza more accurately.

Design: Cross-sectional survey.

Settings: Fifty-two communities/villages in the Wanzhou District, Chongqing, China, a rural area in southwest China, from May 2022 to July 2022.

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Backgrounds: Norovirus is leading cause of non-bacterial gastroenteritis outbreaks globally, characterized by different strains prevalent in different countries and regions.

Methods: Cases were defined as individuals experiencing diarrhea ≥3 times/24 h, and/or vomiting ≥2 times/24 h in two villages between January 28 and February 9, 2021. Investigations were conducted to identify causes.

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Background: There is growing evidence indicating a connection between fine particulate matter (PM) and depressive symptoms. Metabolic risk factors are critical determinants of depressive symptoms. However, the mediating role of these factors on the association between PM and depressive symptoms remains elusive.

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Bacillus cereus (B. cereus) is a common cause of foodborne illness. An outbreak of acute gastrointestinal illness occurred at two middle schools in a rural region of Chongqing, China, in 2021.

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Background: While spicy food is believed to have cardiovascular-protective effects, its impact on hypertension remains uncertain due to conflicting findings from previous studies. This study aimed to explore the association between spicy food and hypertension in Sichuan Basin, China.

Methods: The baseline data of 43,657 residents aged 30-79 in the Sichuan Basin were analyzed including a questionnaire survey (e.

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Background: Exposure to particulate matter with aerodynamic diameters less than 2.5 µm (PM2.5) may increase the risk of 10-year atherosclerotic cardiovascular disease (ASCVD) risk.

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Background: The incidence of stroke in China is increasing, along with a clear trend in the prevalence of risk factors. Alcohol consumption is also a risk factor for stroke. Many cohort studies have explored the relationship between alcohol consumption and stroke risk.

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Context: The relationship between the components of particulate matter with an aerodynamic diameter of 2.5 or less (PM2.5) and bone strength remains unclear.

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Objective: The prevalence of hyperuricemia appears to be high worldwide. We aimed to explore the interaction between harmful alcohol use and tea consumption on hyperuricemia.

Methods: This study recruited 22,449 Han residents based on the data from the China Multi-Ethnic Cohort (CMEC) study, Chongqing province, to have a face-to-face electronic questionnaire, physical examination, and clinical laboratory tests.

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Objectives: Prior research on the effect of tea consumption on blood pressure (BP) generated inconsistent findings. The objective of this study was to explore the effects of different types of tea consumption on BP.

Methods: We included 76,673 participants aged 30-79 from the baseline data of the China Multi-Ethnic Cohort (CMEC) study.

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Article Synopsis
  • This study investigates the link between spicy food intake, the DASH diet score, and the occurrence of stroke among 22,160 Han residents in southwest China over approximately 45 months.
  • Results show that eating spicy food can lower stroke risk by 34% in individuals with low DASH scores, while those with high DASH scores who don't consume spicy food have a 46% lower incidence of stroke.
  • The findings suggest that the protective effects of spicy food and the DASH diet may interact negatively, indicating that their benefits may not work together effectively to reduce stroke risk in those aged 30-79.
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Background: Although there are several cross-sectional and prospective studies on the relationship between sleep duration /insomnia symptoms and depression symptoms, the results of these studies are still not conclusive, and few studies have further analyzed the association between sleep duration and depressive symptoms in adults by gender and age. Thus, this study aimed to investigate the relationship between nocturnal sleep duration and insomnia symptoms with depression symptoms, and further examine whether the association was impacted by age and gender in a large-scale Han Chinese population in southwest China.

Methods: A cross-sectional study was performed that included 44,900 participants from 18 districts in southwest China from September 2018 to January 2019.

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Diet is a major determinant of hyperuricemia, but little is known about the association between diet and hyperuricemia in less-developed multiethnic regions (LMERs). This study aimed to assess the hypothesis that dietary patterns (including 2 a-priori and 3 a posteriori dietary patterns) are associated with hyperuricemia in LMERs. The 2 a priori dietary patterns were the Dietary Approaches to Stop Hypertension (DASH) and the alternative Mediterranean diet (aMED).

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An outbreak of coronavirus disease 2019 (COVID-19) was reported in Yongchuan district of Chongqing, China in March 2022, while the source was unknown. We aimed to investigate the origin and transmission route of the virus in the outbreak. We conducted field investigations for all cases and collected their epidemiological and clinical data.

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What Is Already Known About This Topic?: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant has a stronger transmission capacity and faster transmission speed than the previous strain.

What Is Added By This Report?: The first coronavirus disease 2019 (COVID-19) case infected with the SARS-CoV-2 Omicron subvariant BA.2.

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