The study aims to create engineered bacterial membrane biomimetic nanoparticles (ANG-2 EM@PPC) for targeted drug delivery in glioma treatment, seeking to enhance therapy efficiency.
Methodologies include creating engineered bacteria, preparing nanoparticles, and utilizing various techniques like Western blotting and flow cytometry to analyze their effectiveness in targeting glioma cells.
Animal experiments involved a glioma mouse model to assess the impact of different nanoparticle formulations on tumor distribution and therapeutic potential.