Adamantinoma-like Ewing Sarcoma (ALES) May Harbor FUS Rearrangements : A Potential Diagnostic Pitfall.

Adamantinoma-like Ewing sarcoma (ALES) is a rare malignancy currently considered a variant of Ewing sarcoma with most known cases harboring EWSR1 rearrangements. Herein we present a series of 6 cases of EWSR1 -negative ALES. The tumors arose in the sinonasal tract (n=3), major salivary glands (submandibular gland=1; parotid=1), and anterior mediastinum (n=1) in patients ranging from 25 to 79 years of age.

Approach to a Posterior Cervicomediastinal Ganglioneuroma.

Posterior mediastinal masses centered on the thoracic inlet require a thoughtful operative approach. Herein, a case of a young woman with a symptomatic posterior cervicomediastinal ganglioneuroma is reported to highlight such considerations.