Expression of concern: An impedimetric immunosensor based on diamond nanowires decorated with nickel nanoparticles.

Expression of concern for 'An impedimetric immunosensor based on diamond nanowires decorated with nickel nanoparticles' by Palaniappan Subramanian , , 2014, , 1726-1731, https://doi.org/10.1039/C3AN02045B.

Photonic detection and characterization of DNA using sapphire microspheres.

A microcavity-based deoxyribonucleic acid (DNA) optical biosensor is demonstrated for the first time using synthetic sapphire for the optical cavity. Transmitted and elastic scattering intensity at 1510 nm are analyzed from a sapphire microsphere (radius 500 µm, refractive index 1.77) on an optical fiber half coupler.

Heat-transfer-based detection of SNPs in the PAH gene of PKU patients.

Conventional neonatal diagnosis of phenylketonuria is based on the presence of abnormal levels of phenylalanine in the blood. However, for carrier detection and prenatal diagnosis, direct detection of disease-correlated mutations is needed. To speed up and simplify mutation screening in genes, new technologies are developed.

Toward deep blue nano hope diamonds: heavily boron-doped diamond nanoparticles.

The production of boron-doped diamond nanoparticles enables the application of this material for a broad range of fields, such as electrochemistry, thermal management, and fundamental superconductivity research. Here we present the production of highly boron-doped diamond nanoparticles using boron-doped CVD diamond films as a starting material. In a multistep milling process followed by purification and surface oxidation we obtained diamond nanoparticles of 10-60 nm with a boron content of approximately 2.

An impedimetric immunosensor based on diamond nanowires decorated with nickel nanoparticles.

Nanostructured boron-doped diamond has been investigated as a sensitive impedimetric electrode for the detection of immunoglobulin G (IgG). The immunosensor was constructed in a three-step process: (i) reactive ion etching of flat boron-doped diamond (BDD) interfaces to synthesize BDD nanowires (BDD NWs), (ii) electrochemical deposition of nickel nanoparticles (Ni NPs) on the BDD NWs, and (iii) immobilization of biotin-tagged anti-IgG onto the Ni NPs. Electrochemical impedance spectroscopy (EIS) was used to follow the binding of IgG at different concentrations without the use of any additional label.

Detonation nanodiamond: an organic platform for the suzuki coupling of organic molecules.

Detonation nanodiamond possesses facile surface functional groups and can be chemically processed for many engineering applications. In this work, we demonstrate the functionalization of nanoscale diamond particles with aryl organics using Suzuki coupling reactions. In route one, hydrogenated nanodiamond is derivatized with aryl diazonium to form the bromophenyl-nanodiamond complex, this is subsequently reacted with phenyl boronic acid to generate the biphenyl adduct.

Using detonation nanodiamond for the specific capture of glycoproteins.

We demonstrate here the functionalization of detonation nanodiamond (ND) with aminophenylboronic acid (APBA) for the purpose of targeting the selective capture of glycoproteins from unfractionated protein mixtures. The reacted ND, after blending with the matrix consisting of alpha-cyano-4-hydroxy-cinnamic acid, could be applied directly for matrix-assisted laser desorption ionization (MALDI) assay. A loading capacity of approximately 350 mg of glycoprotein/g of ND could be attained on ND that has been silanized with an alkyl linker chain prior to linking with the phenylboronic acid.