Publications by authors named "Wenfei Yao"

Article Synopsis
  • This study compares the efficacy of two techniques for biliary access during difficult endoscopic retrograde cholangiopancreatography (ERCP): Precut over a pancreatic duct stent (PPDS) and transpancreatic precut sphincterotomy (TPS).
  • A retrospective analysis of data from 864 ERCP patients showed that PPDS had a significantly higher success rate for biliary cannulation (91.3%) compared to TPS (69.6%).
  • Both techniques had similar overall success rates and post-ERCP pancreatitis occurrences, with no significant difference in complications between the two groups.
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  • - The text discusses the issue of cellular senescence, where aging cells accumulate in tissues, hindering the body's ability to heal and regenerate after injury.
  • - Recent research highlights that clearing these senescent cells and improving the tissue environment using biomaterials can enhance the body's regenerative capabilities.
  • - The review aims to shed light on the characteristics of senescent cells and their impact on tissue repair, ultimately suggesting a combined approach of targeting cellular senescence and utilizing biomaterials for better regenerative medicine strategies.
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  • Reactive astrogliosis is a key factor in secondary spinal cord injuries and biomaterials can inhibit astrocyte activation, but the underlying mechanisms are not fully understood.
  • The study identifies the VIM gene as a crucial regulator in reactive astrocytes using whole transcriptome sequencing on a mouse spinal cord injury model, highlighting the role of differentially expressed genes (DEGs) in the extracellular matrix (ECM).
  • The research demonstrates that 3D injectable electrospun fibers effectively reduce reactive astrogliosis by downregulating the VIM gene and disrupting the NF-κB signaling pathway, thus promoting recovery of spinal cord function by preventing further inflammation and neuronal apoptosis.
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Research has demonstrated the positive effect of natural environment on human restoration and well-being. Time spent in nature can often alleviate both physiological and psychological stress. However, few studies have discussed the environmental health effects of the nature's components and characteristics.

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Aim: Given the current aging population, the demand on medical facilities, facilities for elderly care, and even their high prevalence, it is crucial to investigate the advantages of older people. The purpose of our study was to systematically review the existing literature on the health effects of horticultural therapy as a treatment option for the elderly.

Subject And Methods: Article searches were conducted through five databases: Web of science, Science Direct, PubMed, EBSCO, and Google Scholar, according to the standard method of systematic evaluation and meta-analysis.

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With the development of the urban park, people's cognition of the relationship between the environment and public health has been improved, and higher requirements for the living environment have been put forward. As an important group of park users, youths often have different needs regarding the health benefits brought by urban parks. To explore the potential relationship among youth's satisfaction with urban parks, their usage behavior, and health benefit perception, this article presents some constructive suggestions for the development of healthy landscapes in urban parks.

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Background: Aortic dissection (AD) and pulmonary embolism (PE) are both life-threatening disorders. Because of their conflicting treatments, treatment becomes difficult when they occur together, and there is no standard treatment protocol.

Case Summary: A 67-year-old man fell down the stairs due to syncope and was brought to our hospital as a confused and irritable patient who was uncooperative during the physical examination.

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Research suggests that exposure to natural environments can be beneficial for health, such as reducing physical illness and improving mood and cognitive ability. The potential benefits of nature have come into focus at a time when mental health issues are growing globally. Here, we have selected 24 studies from four databases for meta-analysis to explore the effects of exposure to the natural environment on the anxiety of the human body and summarize the influencing factors on the anxiety relief effect.

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There is increasing evidence that the natural environment provides substantial benefits to human emotional well-being. The current study synthesized this body of research using the meta-analysis and assessed the positive and negative effects of exposure to both the natural and built environments. We searched four databases and 20 studies were included in the review.

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Circular RNAs (circRNAs) have a regulatory function on inflammation and autophagy, of which rno-circRNA_010705 (circLrp1b) appears to be significantly up-regulated following traumatic brain injury (TBI). Dexmedetomidine (DEX) shows improvement effects in TBI by inhibiting NLRP3/caspase-1. However, whether circLrp1b plays critical roles in DEX-mediated TBI attenuation and the underlying mechanisms remain unclear.

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Recent studies have reported that Astragalus saponins (AST), extracted from the medicinal plant Astragalus membranaceus, possess anti‑tumor and apoptosis‑inducing abilities on various types of human cancer in vitro and in vivo. However, limited studies have explored how AST impacts glucose metabolism and growth conditions in vitro. The present study aimed to explore cell growth, proliferation, apoptosis and a series of glycolysis metabolic alterations associated with AST treatment in colorectal cancer (CRC) cells.

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Synopsis of recent research by authors named "Wenfei Yao"

  • - Wenfei Yao's recent research primarily focuses on the interplay between natural environments and health outcomes, exploring how exposure to nature can alleviate anxiety and improve overall well-being, as demonstrated through systematic reviews and meta-analyses.
  • - In the field of regenerative medicine, Yao examines innovative therapies such as the use of pro-regenerative biomaterials combined with strategies to inhibit cellular senescence, highlighting the challenges in achieving complete tissue regeneration, especially in aging populations.
  • - Yao also investigates the effects of therapeutic interventions, including horticultural therapy for the elderly and surgical techniques in endoscopic procedures, emphasizing the importance of tailored approaches for improving health outcomes in specific demographics and medical scenarios.