miR-135b: A Potential Biomarker for Pathological Diagnosis and Biological Therapy.

MicroRNAs (miRNAs) are a class of endogenous non-coding RNAs found in eukaryotes with post-transcriptional regulatory functions. A variety of miRNAs is differentially expressed in cancer tissues and thus can be used as biomarkers. microRNA-135b-5p (miR-135b) has been shown to be involved in the pathological processes of a variety of neoplastic and non-neoplastic diseases.

Quality, improvement of soluble dietary fiber from by-products by steam explosion and cellulase modification: Structural and functional analysis.

Steam explosion (SE) and cellulase treatment are potentially effective processing methods for by-products, for use in high-value applications. The treatment conditions were optimized by response surface methodology, increasing the soluble dietary fiber (SDF) yield by 1.52 and 1.

Reactive oxygen species act as the key signaling molecules mediating light-induced anthocyanin biosynthesis in Eucalyptus.

Light plays a pivotal role in regulating anthocyanin biosynthesis in plants, and the early light-responsive signals that initiate anthocyanin biosynthesis remain to be elucidated. In this study, we showed that the anthocyanin biosynthesis in Eucalyptus is hypersensitive to increased light intensity. The combined transcriptomic and metabolomic analyses were conducted on Eucalyptus leaves after moderate (ML; 100 μmol m s) and high (HL; 300 μmol m s) light intensity treatments.

Clinical observation of extraction-site incisional hernia after laparoscopic colorectal surgery.

Background: Laparoscopic colorectal cancer surgery increases the risk of incisional hernia (IH) at the tumor extraction site.

Aim: To investigate the incidence of IH at extraction sites following laparoscopic colorectal cancer surgery and identify the risk factors for IH incidence.

Methods: This study retrospectively analyzed the data of 1614 patients who underwent laparoscopic radical colorectal cancer surgery with tumor extraction through the abdominal wall at our center between January 2017 and December 2022.

The anti-apoptotic role of Ginkgolide B via mitochondrial permeability transition pore inhibition in retinal ischemia-reperfusion.

This research delves into the effectiveness of Ginkgolide B (GB), a compound from Ginkgo biloba, in combating cell death caused by glaucoma, with a focus on mitochondrial impairment and the mitochondrial permeability transition pore (mPTP). Utilizing models of high intraocular pressure and in vitro glaucoma simulations, the study investigates GB's impact on retinal progenitor cells (RPCs) under oxygen-glucose deprivation/reperfusion (OGD/R) and in a rat glaucoma model. The study methodologies included apoptosis assessment, apoptotic marker analysis via Western blot, and mitochondrial structure and function evaluation.

Mechanism of SO/HO enhanced rare earth tailings catalysts in NH-SCR at medium and high temperature.

Rare earth tailings (RET) NH-SCR catalysts were prepared by mechanical and microwave activation of a large amount of rare earth tailings after beneficiation of Bayan Ebo rare earth ore. The effects of SO/HO on the denitrification performance of the RET catalysts were evaluated by conducting denitrification activity tests, SO/HO tolerance tests and DRIFTs mechanistic analysis. The results showed that the denitrification activity was significantly increased in the presence of SO/HO.

Cytokinin promotes anthocyanin biosynthesis via regulating sugar accumulation and MYB113 expression in Eucalyptus.

Anthocyanins are flavonoid-like substances that play important roles in plants' adaptation to various environmental stresses. In this research, we discovered that cytokinin (CK) alone could effectively induce the anthocyanin biosynthesis in Eucalyptus and many other perennial woody plant species, but not in tobacco and Arabidopsis, suggesting a diverse role of CK in regulating anthocyanin biosynthesis in different species. Transcriptomic and metabolomic strategies were used to further clarify the specific role of CK in regulating anthocyanin biosynthesis in Eucalyptus.

Discussion on the influence of optimizing the perioperative management on the recovery after laparoscopic hysterectomy.

The concept of enhanced recovery after surgery (ERAS) was first proposed by Professor Kehlet from the University of Copenhagen in Denmark in 1997. The aim is to optimize multiple perioperative management measures, promote rapid postoperative recovery, shorten hospital stay, and reduce surgical related costs, this article explores the effect of optimizing perioperative bowel preparation and diet management under the strategy of ERAS on the postoperative recovery of patients undergoing laparoscopic hysterectomy for benign gynecological diseases. We selected 90 patients who underwent laparoscopic total hysterectomy for benign gynecological diseases at Hebei General Hospital from June 2018 to June 2019, these patients are between the ages of 40 and 65.

Treatment of primary vaginal malignant melanoma and review of previous literature: A case report.

Introduction: Primary vaginal malignant melanoma is a rare gynecological malignant tumor with high malignancy and poor prognosis. Because of its insidious incidence, it is generally diagnosed in the late stage, and the 5-year survival rate is only 5% to 25%. Due to the rarity of this disease and the limited number of related cases reported in the literature, there is currently no unified standard for its diagnosis and treatment.

Structure characterization and antioxidant activity of abalone visceral peptides-selenium in vitro.

Peptide-selenium chelate is widely regarded as one of the best selenium supplements for relieving selenium deficiency. In this study, abalone visceral peptides (AVP) was used to prepare a new type of peptides-selenium chelate to develop an organic selenium supplement with antioxidant activity. AVP prepared by alcalase exhibited the highest selenium-chelating ability.

Enhancing the Cycle Performance of Lithium-Sulfur Batteries by Coating the Separator with a Cation-Selective Polymer Layer.

Lithium-sulfur batteries are believed to possess the feasibility to power electric vehicles in the future ascribed to the competitive energy density. However, soluble polysulfides continuously shuttle between the sulfur electrode and lithium anode across the separator, which dramatically impairs the battery's capacity. Herein, the surface of a polypropylene separator (PP film) is successfully modified with a delicately designed cation-selective polymer layer to suppress the transport of polysulfides.

Diagnostic value of serum human epididymis protein 4, carbohydrate antigen 125 and their combination in endometrial cancer: A meta-analysis.

Background: To systematically analyze the value of human epididymis protein 4 (HE4) and carbohydrate antigen 125 (CA125) in the diagnosis of endometrial cancer, so as to provide evidence-based medical evidence for the selection of serum tumor markers in the early screening of endometrial cancer.

Methods: We comprehensively searched relevant literature in the Cochrane Library, EMBASE, PubMed, Web of Science, CNKI, VIP, WanFang, and CBM from the date of establishment to November 31, 2021. Quality assessment of diagnostic accuracy studies 2 was applied to evaluate the quality of the included literature.

Transcriptome-Based Construction of the Gibberellin Metabolism and Signaling Pathways in × , and Functional Characterization of and in Regulating Plant Development and Abiotic Stress Adaptations.

Gibberellins (GAs) are the key regulators controlling plant growth, wood production and the stress responses in perennial woody plants. The role of GA in regulating the above-mentioned processes in remain largely unclear. There is still a lack of systematic identification and functional characterization of GA-related genes in .

Evaluation of Mycobacterium tuberculosis specific antigen-stimulated CD27CD38IFN-γCD4 T cells for discrimination of active tuberculosis.

Background: Active tuberculosis (ATB) originates from primary Mycobacterium tuberculosis (MTB) infection or reactivation of latent tuberculosis. Besides bacteriological examination, MTB-reactive immunocytes detection can be an alternative testing for discrimination of active tuberculosis. The purpose of this study is to investigate the accuracy of peripheral blood CD27CD38IFN-γCD4T cells in ATB diagnosis.

First Report of Powdery Mildew in Eucalyptus Caused by Erysiphe neolycopersici in China.

Eucalyptus is one of the most fast-growing and widely planted hardwood trees in the tropical and subtropical regions (Grattapaglia and Kirst, 2008). In December 2021, powdery mildew diseases were observed on the , × , × , and trees growing in the Eucalyptus garden of the Guangxi University campus in Nanning (108°22'E, 22°48'N) of Guangxi Zhuang Autonomous Region, where is the main plantation area for Eucalyptus. The spread of this disease would bring potential challenges on the Eucalyptus plantation management in this region of China.

Low temperature NH-SCR performance and mechanism of Mn and Fe supported CeCOF-monazite catalysts.

The group has shown that Baiyun Ebo rare earth concentrate has excellent performance in NH-SCR denitrification when used as a carrier, where rare earth elements are mainly present in cerium fluorocarbon ore (CeCOF) and monazite (CePO) mineral phases. In this paper, a new low-temperature NH-SCR catalyst of Mn-Fe/CeCOF-monazite was prepared by an impregnation method, using synthetic CeCOF and purified monazite as carriers. By exploring its denitrification performance and mechanistic analysis, it provides theoretical guidance for the use of rare earth concentrates as low-temperature NH-SCR catalysts.

Study on the mechanism of synthetic (Ce,La)COF sulfuric acid acidification and NH-SCR loaded with Mn and Fe.

A hydrothermal method was used to synthesise (Ce,La)COF grain simulated minerals, in accordance with the Ce-La ratio of bastnaesite in the mineralogy of the Bayan Ebo process. The NH-SCR catalytic activity of the synthesised (Ce,La)COF was improved by loading transition metals Mn and Fe and sulphuric acid acidification treatments. The activity test results showed that the catalysts which were simultaneously acidified with sulphuric acid and loaded with transition metals Mn and Fe had a NO conversion of 92% at 250 °C.

Determination of free fatty acids in Antarctic krill meals based on matrix solid phase dispersion.

Amino-modified mesoporous silicawas prepared by modifying mesoporous silica with 3-aminopropyltriethoxysilane and used as adsorbents in matrix solid-phase dispersion (MSPD) to analyze free fatty acids (FFAs) in krill meals for the first time. The adsorption-desorption experiments and Fourier-transform infrared spectroscopy showed amino-modified mesoporous silica with ordered mesoporous structure was successfully synthesized. The adsorption experiments including static and dynamic adsorption showed thatabsorption capacity of amino-modified mesoporous silica towards FFAs was better than that of aminated silicon microspheres at all concentrations.

Construction of Glycogen-Based Nanoparticles Loaded with Resveratrol for the Alleviation of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease.

The purpose of this study was to construct a glycogen (Gly)-based nanoparticle (NP) with liver-targeted and redox response to effectively deliver resveratrol (Res) for improving nonalcoholic fatty liver disease (NAFLD). Herein, Gly was modified using α-lipoic acid (α-LA) and lactobionic acid (Lac) to obtain an amphiphilic polymer (Gly-LA-Lac), which was self-assembled in water and then encapsulated in Res to form Res NPs with excellent stability. As expected, the Res NPs exhibited liver-targeted and redox response release behavior.

Optimization of ultrasound assisted extraction of abalone viscera protein and its effect on the iron-chelating activity.

This study aims to investigate effects of ultrasound assisted extraction on the abalone viscera protein extraction rate and iron-chelating activity of peptides. The optimal conditions for ultrasound assisted extraction by response surface methodology was at sodium hydroxide concentration 14 g/kg, ultrasonic power 428 W and extraction time 52 min. Under the optimal conditions, protein extraction rate was 64.

Age-Related Retinal Changes in Wild-Type C57BL/6J Mice Between 2 and 32 Months.

Purpose: The purpose of this study was to extend our understanding of how aging affects normal retina function and morphology in wild-type C57BL/6J mice, by analyzing electrophysiological recordings and in vivo and post mortem anatomy.

Methods: Electroretinograms (ERGs), spectral domain optical coherence tomography (SD-OCT), and confocal scanning laser ophthalmoscope (cSLO) in vivo images were obtained from mice between the ages of 2 and 32 months in four groups: group 1 (<0.5 years), group 2 (1.

Density functional theory study on adsorption of L-cysteine by Y, Zr, Nb, Mo-doped graphenes.

The adsorption properties of l-cysteine (L-cys) on [Kr] 4d (Y-Mo) doped graphenes with single and double vacancies are studied using density functional theory calculations with dispersion correction. The results showed that Y, Zr, Nb and Mo doped single-vacancy and double-vacancy graphenes show chemical adsorption characteristics towards L-cys. For the respective S, O and N-end adsorption, the binding strengths of L-cys on XSVs decrease from Y to Nb, and then increase.

Food protein-derived iron-chelating peptides: The binding mode and promotive effects of iron bioavailability.

Iron is known as an essential nutrient in the human body. Insufficient iron uptake is easy to result in iron deficiency anemia, which is a public health problem in both developing and developed countries. Iron, complexed by iron-chelating peptides, have been proposed as a superior candidate to ionized iron for improving iron absorption and bioavailability.

Surface Properties and Denitrification Performance of Impurity-Removed Rare Earth Concentrate.

Acid leaching and alkali roasting were used to remove impurities such as Ca and Si in Baiyun Obo rare earth concentrate. The effects of acid-base treatment on the physical and chemical properties of the samples were analyzed by scanning electron microscopy, X-ray diffraction, Brunauer-Emmett-Teller characterization, X-ray photoelectron spectroscopy, H-temperature-programmed reduction, NH-temperature-programmed desorption (TPD), and NO-TPD. Results showed that the content of CeO in the rare earth concentrates increased and the dispersion was uniform.