Assessment of neonatal ventilation during high-frequency oscillatory ventilation.

Objective: To determine alterations in high-frequency oscillatory ventilation (HFOV) performance during clinical ventilator management.

Design: Clinical investigation.

Setting: Two level III intensive care nurseries in Wilmington, Delaware, and Philadelphia, Pennsylvania.

Homocysteine levels in preterm infants: is there an association with intraventricular hemorrhage? A prospective cohort study.

Background: The purpose of this study was to characterize total homocysteine (tHcy) levels at birth in preterm and term infants and identify associations with intraventricular hemorrhage (IVH) and other neonatal outcomes such as mortality, sepsis, necrotizing enterocolitis, bronchopulmonary dysplasia, and thrombocytopenia.

Methods: 123 infants < 32 weeks gestation admitted to our Level III nursery were enrolled. A group of 25 term infants were enrolled for comparison.