Associations Between the Dietary Inflammatory Index, Brain Volume, Small Vessel Disease, and Global Cognitive Function.

Background: An inflammatory diet is related to poorer cognition, but the underlying brain pathways are unknown.

Objective: The aim of this study was to examine associations between the Energy-Adjusted Dietary Inflammatory Index (E-DII) and brain volume, small vessel disease, and cognition in people with and without type 2 diabetes mellitus (T2DM).

Design: This is a secondary cross-sectional analysis of data from the Cognition and Diabetes in Older Tasmanians study.