Effect of sequential embryo transfer on fertilization and embryo transfer outcomes: a systematic review and meta-analysis.

Background: Sequential embryo transfer has been recognized as a strategy to increase pregnancy rates in women undergoing fertilization and embryo transfer (IVF-ET). However, its impact on assisted reproductive outcomes remains to be substantiated by robust evidence. This systematic review aims to summarize and analyze the available evidence to investigate the effect of sequential embryo transfer on assisted reproductive outcomes.

Thyroid hormone induce a p53-dependent DNA damage through PI3K/Akt activation in sperm.

Accumulating evidences showed that thyroid hormone was participated in the functioning of the reproductive system, and an elevated level of thyroid hormones had a negative impact on reproductive system. However, the molecular basis for this observation still remains to be fully understood. Here, we show that l-Thyroxine significantly impaired human sperm motility.