Publications by authors named "Wenbo Tan"

Background: Ticks are blood-feeding significant arthropods that can harbour various microorganisms, including pathogens that pose health risks to humans and animals. Tick-symbiont microorganisms are believed to influence tick development, but the intricate interactions between these microbes and the relationships between different tick-borne microorganisms remain largely unexplored.

Results: Based on 111 tick pool samples presenting questing and engorged statuses including 752 questing tick and 1083 engorged tick from cattle and goats, which were collected in two types of geographic landscape (semi-desert and alpine meadow).

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Anaplasma bovis (1), Bartonella krasnovii (3), and Bartonella sp. (17) were detected in 80 Libyan jirds (Meriones libycus) from China. These findings extend the known host and geographic ranges of these pathogens, with neither A.

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  • - A new species of flea from the Vermipsyllidae family was discovered in sheep in China, alongside the detection of the Rickettsia raoutii bacteria in some fleas.
  • - The study involved collecting 128 fleas from pastured sheep, with eight selected for detailed morphological analysis and genetic testing to identify the fleas and their associated bacteria.
  • - The morphological traits of the newly identified flea were similar to Vermipsylla alakurt, but genetic sequences revealed some differences, highlighting the complexity of flea identification and its implications for understanding flea-borne diseases.
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Forty-five tick species have been recorded in Kazakhstan. However, their genetic diversity and evolutionary relationships, particularly when compared to ticks in neighbouring countries, remain unclear. In the present study, 148 mitochondrial cytochrome c oxidase subunit I (COI) sequence data from our laboratory and NCBI (National Center for Biotechnology Information; https://www.

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Background: Rodents play an important role in the life cycle of ixodid and argasid ticks, particularly as hosts of larvae and nymphs. The great gerbil (Rhombomys opimus), the preferred prey item of several carnivores (e.g.

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  • MARCH family proteins, particularly MARCH1, MARCH2, and MARCH8, inhibit Ebola virus replication by blocking the maturation of its glycoprotein (GP).
  • MARCH1 and MARCH2 reduce the presence of EBOV GP on the cell surface and hinder the infectivity of EBOV GP-pseudotyped viruses.
  • The study highlights that the host enzyme furin interacts with MARCH1/2 and EBOV GP, suggesting a conserved mechanism among mammalian MARCH proteins that could inform future antiviral strategies.
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  • The Himalayan marmot serves as a reservoir for brucellosis, but the specific changes in their blood biochemistry when infected with Brucella are not well-understood.
  • The study aimed to investigate hematologic and biochemical changes in 24 Brucella-infected marmots compared to 24 non-infected ones through blood sample analysis.
  • Findings revealed significant increases in immune-related blood cell counts and a decrease in carbon dioxide combining power, suggesting an immune response to Brucella infection; further research is needed to fully understand these effects.
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Osseous cystic echinococcosis (CE) is a rare disease caused by Echinococcus granulosus, which is characterized by high morbidity, disability, and mortality. However, it is severely neglected due to its mainly regional epidemic. The development of osseous CE is usually accompanied by severe bone erosion and destruction at the site of infection; however, there is a gap in research on the mechanism of this phenomenon.

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Sugar beets are an important crop for global sugar production. Intense drought and the increasing lack of water resources pose a great threat to sugar beet cultivation. It is a priority to investigate favourable germplasms and functional genes to improve the breeding of drought tolerant plants.

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Background: Sugar beet (Beta vulgaris L.) is an economically essential sugar crop worldwide. Its agronomic traits are highly diverse and phenotypically plastic, influencing taproot yield and quality.

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Leaf spot disease caused by Sacc. is the most damaging foliar disease threatening sugar beet production worldwide. The wide spread of disease incurs a reduction of yield and economic losses.

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Nitrogen (N) is an essential macronutrient for plants, acting as a common limiting factor for crop yield. The application of nitrogen fertilizer is related to the sustainable development of both crops and the environment. To further explore the molecular response of sugar beet under low nitrogen (LN) supply, transcriptome analysis was performed on the LN-tolerant germplasm '780016B/12 superior'.

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Sugar beet is a main sugar crop worldwide that often faces drought stress. The identification of drought tolerance of sugar beet germplasms is beneficial for breeding, but the research about it has been rarely reported. In this study, the drought tolerance of germplasms 92005-1, 94002-2 and 92021-1-1 was tested under simulated conditions.

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Tacheng tick virus 1 (TcTV-1) and Songling virus (SGLV) were originally found in human patients in China who had had tick bites. Tamdy virus (TAMV) was detected for the first time in a tick-infested person from Kyrgyzstan in 1973. In this study, 276 great gerbils (Rhombomys opimus) were collected in Xinjiang Uygur Autonomous Region in northwestern China.

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Nitrogen (N) is an essential element required for sugar beet growth. Sugar beets with low N (LN) tolerance and high N use efficiency are excellent materials for breeding. Here, we comprehensively evaluated the morphological and physiological responses of nine sugar beet genotypes to LN supply.

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Understanding the response and tolerance mechanisms of nitrogen (N) stress is essential for the taproot plant of sugar beet. Hence, in this study, low (0.5 and 3 mmol/L; N0.

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Purpose: To date, ten validated Arthrostoma species were reported. Here, a new hookworm species was found from Asian badger (Meles leucurus).

Methods: Nineteen hookworms (9 males and 10 females) were collected from the small intestine of two Asian badgers in Xinjiang Uygur Autonomous Region, northwestern China.

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Demyelination disease as diabetes mellitus (DM) complication is characterized by apoptosis of Schwann cells (SCs) and several reports have demonstrated that high glucose content can induce an inflammation response and lead to the apoptosis of SCs. For NF-κB plays a pivotal role in the inflammatory response, hence we hypothesized that high glucose content can induce inflammation though the NF-κB pathway. First we verified that 150 mM high glucose can increase the expression of cleaved caspase 3, interleukin (IL)- 1β, Cyto-C and NF-κB with time through Western blot and increase the apoptosis of RSC96s through Flow Cytometry.

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To clarify the mechanism of the response of sugar beet ( L.) to cadmium (Cd) stress, this study investigated changes in the phenotype, physiological indexes, and subcellular structure of under Cd treatment and the transcriptional pattern of the gene (a heavy metal-associated isoprenylated plant protein involved in heavy metal detoxification). The plant height and shoot and root growth of seedlings were inhibited to some extent under 0.

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The Eurasian lynx () is a medium-sized wild cat species distributed throughout Eurasia. There has been no report on species (Cestoda: Cyclophyllidea) infecting this felid in China. In this study, 24 tapeworms were found in two Eurasian lynxes (#1 and #2) in Xinjiang Uygur Autonomous Region (XUAR), northwestern China.

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endocarditis is a fatal complication and the most frequent cause of death for human brucellosis. This study aimed to systematically review the literature on the follow-up outcomes of endocarditis and analyze the determinants affecting the follow-up outcomes. The databases PubMed, Web of Science, Embase, and Cochrane were searched using keywords and suitable combinations.

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The great gerbil (), widely distributed in Asia, is a natural reservoir for , and some species of helminths. In this study, 188 great gerbils were sampled in Alataw City and Manas County, northwestern China, and tested for the presence of , and species by molecular methods. sp.

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Background: Previously, twelve Rickettsia species were identified in ticks, fleas, sheep keds (Melophagus ovinus), bats (Pipistrellus pipistrellus) and a tick-bitten patient in the Xinjiang Uygur Autonomous Region (XUAR) in northwestern China. Here we aimed to molecularly detect rickettsial agents in red fox (Vulpes vulpes), marbled polecat (Vormela peregusna) and their ticks.

Methods: During 2018-2019, 12 red foxes, one marbled polecat and their ticks were sampled in two counties and a city of the XUAR.

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Apela, a novel endogenous peptide ligand for the G-protein-coupled apelin receptor, was first discovered and identified in human embryonic stem cells in 2013. Apela has showed some biological functions in promoting angiogenesis and inducing vasodilatation of mammals by binding apelin receptor, but little is known about its expression characteristics and regulatory mechanism in chicken. In the present study, the coding sequences of Apela in chicken was cloned.

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