Sustained transdermal delivery of human growth hormone from niosomal gel: and studies.

Human growth hormone (hGH) is widely used to treat several diseases for decades. However, the current treatment regime requires frequent injections subcutaneous route due to short half-life, which leads to pain and poor patient compliance. In this study, a novel transdermal (non-invasive) hGH loaded niosomes gel was prepared to reduce the frequency of subcutaneous injections and to improve the patient compliance.