Publications by authors named "WenXin Liu"

A novel β-amyloid protein capillary microextraction column was designed and prepared using epitope molecular imprinting technology for specific recognition of trace β-amyloid proteins in complex biological matrices. Using N-terminal nonapeptide of β-amyloid protein as template molecule, choline chloride-MAA and N-hydroxymethyl acrylamide as functional monomers, ethylene glycol dimethacrylate as crosslinker, the imprinted capillary monolithic column was prepared by thermal polymerization in the acetonitrile-water system. The optimal preparation parameters were obtained with the ratio of template: functional monomer: crosslinker at 1:6:16 (mmol/mmol/mmol).

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Background: Parkinson's disease (PD) is currently the second most common degenerative neurological disorder globally, with aspiration pneumonia caused by difficulty swallowing being the deadliest complication. The patient's subjective experience and the safety of swallowing have been the main focus of previous evaluations and treatment plans. The effectiveness of treatment may be attributed to the brain's ability to adapt and compensate.

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Certain neonicotinoid metabolites (mNEOs) are causing widespread concern because they are equally or even more toxic than the parent NEOs. Currently, there is limited information on the distribution of mNEOs in soil. Especially, it is unknown that the effects of agricultural factors, such as plastic filming, plowing, irrigation, and fertilization, on mNEOs.

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How carbon (sucrose) and nitrogen (amino acid) accumulation is coordinatively controlled in cereal grains remains largely enigmatic. We found that overexpression of the strigolactone (SL) biosynthesis gene CAROTENOID CLEAVAGE DIOXYGENASE 8 (CCD8) resulted in greater ear diameter and enhanced sucrose and amino acid accumulation in maize kernels. Loss of ZmCCD8 function reduced kernel growth with lower sugar and amino acid concentrations.

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Objective: Thin endometrium caused by various factors affects the conception rate of females worldwide; however, current medications are still insufficient. Therefore, a novel approach is needed. We previously reported the effect of menstrual blood-derived mesenchymal stem cells (MenSCs) in ameliorating ethanol-induced endometrial injuries.

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Harmful algal blooms (HABs) - proliferated algae densities, often producing toxins - have increasingly been found in ocean and coastal areas. Recent studies show that rising temperatures contribute to HAB occurrence, but the broader influence of climate change on these outbreaks is less quantified. Of particular concern is the limited research on HAB toxin effects under varying temperatures, especially regarding primary consumers such as copepods, a crucial component of aquatic ecosystems.

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Despite the increasing concern regarding the ecological risks posed by per- and polyfluoroalkyl substances (PFAS), a lack of comprehensive understanding of their actual ecotoxicity remains. Through a meticulous examination of 91 peer-reviewed studies investigating effects at a population level and constructing probabilistic species sensitivity distributions (PSSDs), we present a state-of-the-science hazard assessment of PFAS in freshwater species. Using data subsets containing suboptimal data led to an overestimation of the predicted no-effect concentrations (PNECs) of PFAS.

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  • A new functional material was created to detect aflatoxins in Chinese herbal medicines by using a molecularly imprinted polymer (MIP) with ethyl coumarin-3-carboxylate as a pseudo-template.
  • The synthesized MIP demonstrated effective aflatoxin adsorption and had successful physical properties confirmed by various analyses, achieving high recovery rates in lab tests.
  • This method for preparing MIPs is noted for being simple and cost-effective, making it a promising approach for detecting aflatoxins in complex samples.
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  • Drought stress (DS) significantly impacts plant health and agriculture, leading to reduced crop yields and limiting growth in certain regions.
  • To combat DS, researchers are exploring various exogenous substances (ESs) that can help plants tolerate this stress, focusing on their specific effects and mechanisms.
  • The paper categorizes these ESs based on their roles in enhancing osmotic adjustment, improving antioxidant pathways, promoting photosynthesis, boosting plant nutrition, and regulating phytohormones, while also discussing strategies for effective application in agriculture to address challenges from droughts.
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  • Environmental persistent free radicals (EPFRs) are new pollutants linked to oxidative stress and serious health issues, primarily formed from aromatic compounds like polycyclic aromatic hydrocarbons (PAHs).
  • This study measured EPFR levels in industrial soils highly contaminated by PAHs, finding significantly higher concentrations near industrial plants compared to surrounding areas.
  • A notable correlation was identified between PAHs and EPFRs concentration, with soil organic matter showing a complex relationship that may inhibit EPFR formation, suggesting the need for further investigation in future studies.
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  • Ion exchange chromatography-tandem mass spectrometry (IEC-MS/MS) is a new technique developed for quickly detecting chlorate and perchlorate residues in tea samples.
  • The optimal process involves ultrasonic extraction with a methanol-water mix, followed by purification using a specific solid-phase extraction column, and employs exact conditions for separation and detection.
  • Tests showed high accuracy, with excellent linearity for the substances tested across a range of concentrations, and successful application in analyzing 15 tea samples from a local market.
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  • - A novel magnetic nanomaterial, C18-PS-DVB-FeO, was created using FeO as the core and PS-DVB as the shell, providing excellent chemical stability and magnetic properties for effective extraction in environmental applications.
  • - A magnetic dispersive solid phase extraction (Mag-dSPE) method was developed to analyze food additives in river water, using C18-PS-DVB-FeO as an adsorbent combined with high-performance liquid chromatography (HPLC) for precise detection.
  • - The method successfully detected 11 food additives with limits of detection between 0.6-3.1 μg/L and showed high recovery rates, while the nanomaterial maintained extraction efficiency after five reuse
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  • The study examines how m6A methylation in wheat is affected by drought stress, finding that TaETC9 may help regulate drought tolerance through RNA methylation.
  • Researchers identified 4221 m6A peaks in 3733 genes, with 373 peaks showing different expressions under drought conditions compared to control conditions.
  • The results indicate that higher levels of m6A are linked to increased mRNA abundance, and the deletion of TaETC9 increased drought sensitivity, suggesting its essential role in drought resistance in wheat.
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  • Recent advancements in biosensors using odorant-binding proteins (OBPs) allow for the detection of odorants and pheromones, though challenges remain in detecting aldehydes effectively.
  • A new OBP2a-based electrochemical impedance spectroscopy (EIS) biosensor was created, showing high sensitivity and selectivity for specific aldehydes while minimizing interference from other substances.
  • The biosensor demonstrated excellent repeatability, stability, and recovery rates, indicating its potential applications in medical diagnostics, food analysis, and environmental monitoring.
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Background: Anterior cruciate ligament (ACL) injuries are common among physically active individuals, and obesity may increase the risk of such injuries due to factors like biomechanical stress on the knee. We aimed to determine if obesity affects postoperative outcomes after ACL reconstruction.

Methods: Data from adults aged 20 years and older with ACL injuries who underwent inpatient reconstruction from 2005 to 2018 were extracted from the United States (US) Nationwide Inpatient Sample (NIS) database.

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Based on the panel data of 75 cities in the Yellow River Basin from 2000 to 2020, this manuscript measures the agricultural low-carbon production efficiency scientifically through the Super-SBM model. In addition, the deviation degree of agricultural industry is used as the index of structural adjustment. Finally, the spatial Durbin model is used to analyze the effect direction and degree of structural adjustment, financial support, and their synergistic effect on agricultural low-carbon production efficiency.

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Based on panel data of 31 provinces in rural China from 1997 to 2020, this manuscript first applies a carbon reduction and sequestration (CRS) model from the perspective of agricultural carbon emissions and agricultural carbon sinks. We then construct a food security evaluation system to examine the four dimensions of quantity, quality, ecological and economic security. Finally, the study uses a spatial Durbin model to empirically analyze the impact of CRS on food security and the moderating effect of fiscal decentralization.

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Soil bacteria are an important part of the forest ecosystem, and they play a crucial role in driving energy flow and material circulation. Currently, many uncertainties remain about how the composition and distribution patterns of bacterial communities change along altitude gradients, especially in forest ecosystems with strong altitude gradients in climate, vegetation, and soil properties. Based on dynamic site monitoring of the Baiyun Mountain Forest National Park (33°38'-33°42' N, 111°47'-111°51' E), this study used Illumina technology to sequence 120 soil samples at the site and explored the spatial distribution mechanisms and ecological processes of soil bacteria under different altitude gradients.

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In this work, steam explosion (SE) was applied to prompt the rapid extraction of ergosterol and polysaccharides from root (FVR) waste. Ultrasound-assisted saponification extraction (UASE) followed by water extraction was used to prepare ergosterol and polysaccharides. The results indicated that SE destroyed the complicated structure of FVR and increased its internal porosity and surface roughness.

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Black phosphorus (BP) has attracted much attention due to its excellent physiochemical properties. However, due to its biodegradability and simple antibacterial mechanism, using only BP nanomaterials to combat bacterial infections caused by drug-resistant pathogens remains a significant challenge. In order to improve the antibacterial efficiency and avoid the emergence of drug resistance, BP nanomaterials have been combined with other functional materials to form black phosphorus-based antibacterial nanoplatform (BPANP), which provides unprecedented opportunities for the treatment of drug-resistant infections.

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Background: Ion channels play an important role in tumorigenesis and progression of cervical cancer. Multiple long non-coding RNA genes are widely involved in ion channel-related signaling regulation. However, the association and potential clinical application of lncRNAs in the prognosis of cervical cancer are still poorly explored.

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Background: Although various anti-inflammatory medicines are widely recommended for osteoarthritis (OA) treatment, no significantly clinical effect has been observed. This study aims to examine the effects of vitamin B6, a component that has been reported to be capable of alleviating inflammation and cell death in various diseases, on cartilage degeneration in OA.

Methods: Collagen-induced arthritis (CIA) mice model were established and the severity of OA in cartilage was determined using the Osteoarthritis Research Society International (OARSI) scoring system.

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Purpose: The aim to assess treatment failure in patients with stage III colon cancer who underwent radical surgery and was analyzed using the nomogram.

Methods: Clinical factors and survival outcomes for stage III colon cancer patients registered in the SEER database from 2018 to 2019 were analyzed, with patients split into training and testing cohorts (7:3 ratio). A total of 360 patients from the First Affiliated Hospital of Longyan served as an external validation cohort.

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Farmland transfer is a critical component in facilitating agricultural scale management and improving agricultural production efficiency. This study examines the spatial distribution of farmland transfer in China and identifies the factors influencing it, offering valuable guidance for advancing China's farmland transfer practices. Through the application of mathematical statistics and GIS spatial analysis, the study investigates changes in spatial patterns related to the scale, rate, mode, and recipients of farmland transfer across China's 30 provinces from 2015 to 2020.

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