Three-Dimensional Weld Pool Monitoring and Penetration State Recognition for Variable-Gap Keyhole Tungsten Inert Gas Welding Based on Stereo Vision.

K-TIG welding offers the advantages of single-sided welding and double-sided formation, making it widely used for medium/thick-plate welding. The welding quality of K-TIG is closely linked to its penetration state. However, the assembly gap in medium/thick-plate workpieces can easily result in an unstable penetration state.

Identification and verification of the role of key metabolites and metabolic pathways on ASFV replication.

African swine fever virus (ASFV) infection usually causes viremia within a few days. However, the metabolic changes in pig serum after ASFV infection remain unclear. In this study, serum samples collected from ASFV-infected pigs at different times were analyzed using pseudotargeted metabolomics method.

DDX20: A Multifunctional Complex Protein.

DEAD-box decapping enzyme 20 (DDX20) is a putative RNA-decapping enzyme that can be identified by the conserved motif Asp-Glu-Ala-Asp (DEAD). Cellular processes involve numerous RNA secondary structure alterations, including translation initiation, nuclear and mitochondrial splicing, and assembly of ribosomes and spliceosomes. DDX20 reportedly plays an important role in cellular transcription and post-transcriptional modifications.

Facile Synthesis of Polymer-Reinforced Silica Aerogel Microspheres as Robust, Hydrophobic and Recyclable Sorbents for Oil Removal from Water.

With the rapid development of industry and the acceleration of urbanization, oil pollution has caused serious damage to water, and its treatment has always been a research hotspot. Compared with traditional adsorption materials, aerogel has the advantages of light weight, large adsorption capacity and high selective adsorption, features that render it ideal as a high-performance sorbent for water treatment. The objective of this research was to develop novel hydrophobic polymer-reinforced silica aerogel microspheres (RSAMs) with water glass as the precursor, aminopropyltriethoxysilane as the modifier, and styrene as the crosslinker for oil removal from water.

African swine fever virus MGF360-9L promotes viral replication by degrading the host protein HAX1.

African swine fever virus (ASFV) infection causes African swine fever (ASF), a virulent infectious disease that threatens the safety of livestock worldwide. Studies have shown that MGF360-9 L is important for the virulence of ASFV and the host protein HS1-associated protein X-1 (HAX1) plays an important role in viral pathogenesis. This study aimed to clarify the mechanism by which HAX1 mediates ASFV replication through interactions with MGF360-9 L.

Metabolomic analysis of pig spleen reveals African swine fever virus infection increased acylcarnitine levels to facilitate viral replication.

African swine fever (ASF) is a devastating disease caused by the African swine fever virus (ASFV) that adversely affects the pig industry. The spleen is the main target organ of ASFV; however, the function of metabolites in the spleen during ASFV infection is yet to be investigated. To define the metabolic changes in the spleen after ASFV infection, untargeted and targeted metabolomics analyses of spleens from ASFV-infected pigs were conducted.

An urchin-shaped covalent organic framework with rich nitrogen for efficient removal of neonicotinoid insecticides in honey and fruits.

Neonicotinoid insecticides (NEOs) are widely used because of their high efficiency, low dosage and long duration. However, the residues of NEOs could cause the collapse of bee population and even threaten human health. Herein, an urchin-shaped covalent organic framework with rich nitrogen (U-COF) was synthesized with 2,4,6-tri(4-aminophenyl)-1,3,5-triazine (TZT) and 2,5-divinyl-1,4-benzaldehyde (DVA) by adjusting the catalyst (acetic acid) concentration for adsorptive removal of NEOs.

Proteins in pregnant swine serum promote the African swine fever virus replication: an iTRAQ-based quantitative proteomic analysis.

African swine fever (ASF) is a severe infectious disease caused by the African swine fever virus (ASFV), seriously endangering the global pig industry. ASFV possesses a large genome, strong mutation ability, and complex immune escape mechanisms. Since the first case of ASF was reported in China in August 2018, it has had a significant impact on social economy and food safety.

Magnetic boron nitride adorned with Pd nanoparticles: an efficient catalyst for the reduction of nitroarenes in aqueous media.

Hexagonal boron nitride (h-BN) is an excellent support material for nanocatalysts due to its two-dimensional (2D) architectural morphology and physicochemical stability. In this study, a chemically stable, recoverable, eco-friendly, and magnetic h-BN/Pd/FeO catalyst was prepared by a one-step calcination process, in which Pd and FeO nanoparticles (NPs) were uniformly decorated on the surface of h-BN a typical adsorption-reduction procedure. In detail, nanosized magnetic (Pd/FeO) NPs were derived from a Prussian blue analogue prototype, a well-known porous metal-organic framework, and then further surface-engineered to produce magnetic BN nanoplate-supported Pd nanocatalysts.

PI3K-Akt pathway-independent PIK3AP1 identified as a replication inhibitor of the African swine fever virus based on iTRAQ proteomic analysis.

African swine fever (ASF) is a severe infectious disease that has a high global prevalence. The fatality rate of pigs infected with ASF virus (ASFV) is close to 100%; in the absence of a safe and reliable commercial vaccine, this poses a threat to the global pig industry and public health. To better understand the interaction of ASFV with its host, isobaric tags for relative and absolute quantitation combined with liquid chromatography-mass spectrometry was used to conduct quantitative proteomic analysis of bone marrow-derived macrophage cells infected with ASFV.

Identification and analysis of the interaction network of African swine fever virus D1133L with host proteins.

African swine fever (ASF) is a contagious and lethal hemorrhagic disease in pigs; its spread results in huge economic losses to the global pig industry. ASF virus (ASFV) is a large double-stranded DNA virus encoding >150 open reading frames. Among them, ASFV-encoded D1133L was predicted to be a helicase but its specific function remains unknown.

ZBP1: A Powerful Innate Immune Sensor and Double-Edged Sword in Host Immunity.

Z-conformation nucleic acid binding protein 1 (ZBP1), a powerful innate immune sensor, has been identified as the important signaling initiation factor in innate immune response and the multiple inflammatory cell death known as PANoptosis. The initiation of ZBP1 signaling requires recognition of left-handed double-helix Z-nucleic acid (includes Z-DNA and Z-RNA) and subsequent signaling transduction depends on the interaction between ZBP1 and its adapter proteins, such as TANK-binding kinase 1 (TBK1), interferon regulatory factor 3 (IRF3), receptor-interacting serine/threonine-protein kinase 1 (RIPK1), and RIPK3. ZBP1 activated innate immunity, including type-I interferon (IFN-I) response and NF-κB signaling, constitutes an important line of defense against pathogenic infection.

Highly water-dispersible hydroxyl functionalized covalent organic frameworks as matrix for enhanced MALDI-TOF MS identification and quantification of quaternary ammonium salts in water and fruits.

A composite matrix of sodium alginate (SA) and COF (Tp-DHBD) was designed and prepared for the detection of quaternary ammonium salts (QAs) containing heteroatoms. SA@Tp-DHBD self-assembled by the hydrogen bonding interaction between SA and COF has abundant hydroxyl and carboxylate anion sites, which makes for the excellent enrichment of the QAs through multiple interactions. Besides, the abundant hydroxyl groups can enhance laser absorption and energy transfer to achieve sensitive detection.

Facile synthesis disposable MOF membrane filter: Growth of NH-MIL-125 (Ti) on filter paper for fast removal of organophosphorus pesticides in aqueous solution and vegetables.

Metal-organic frameworks (MOFs) have great potential to remove pesticide residues. However, the lack of affinity between the materials and target and the process of trivial sample preparation resulted in limited removal efficiency. Here, we report a one-pot method for the fast preparation of NH-MIL-125 (Ti)-based filter paper to synthesise NH-MIL-125 (Ti)-based filter paper membranes.

Profiling and functional analysis of differentially expressed circular RNAs identified in foot-and-mouth disease virus infected PK-15 cells.

Circular RNAs (circRNAs) are a new type of endogenous noncoding RNA that exhibit a variety of biological functions. However, it is not clear whether they are involved in foot-and-mouth disease virus (FMDV) infection and host response. In this study, we established circRNA expression profiles in FMDV-infected PK-15 cells using RNA-seq (RNA-sequencing) technology analysis.

Thermal and Mechanical Performances of the Superflexible, Hydrophobic, Silica-Based Aerogel for Thermal Insulation at Ultralow Temperature.

A superflexible hydrophobic silica-based aerogel (FHSA) was prepared via a facile sol-gel process and ambient pressure drying method. The FHSA was treated at different temperatures varying from -196 to 450 °C to evaluate its thermal and mechanical performances. The evolutions of the physical property, hydrophobicity, microstructure, pore structure, and chemical structure of the FHSA with the various treatment temperatures were investigated comprehensively.

Chemical Surface Adsorption and Trace Detection of Alcohol Gas in Graphene Oxide-Based Acid-Etched SnO Aerogels.

An acidified SnO/rGO aerogel (ASGA) is an attractive contributor in ethanol gas sensing under ultralow concentration because of the sufficient active sites and adsorption pores in SnO and the rGA, respectively. Furthermore, a p-n heterojunction is successfully constructed by the high electron mobility between ASP and rGA to establish a brand-new bandgap of 2.72 eV, where more electrons are released and the surface energy is decreased, to improve the gas sensitivity.

Rapid spread of tomato yellow leaf curl virus in China is aided differentially by two invasive whiteflies.

Background: Tomato yellow leaf curl virus (TYLCV) was introduced into China in 2006, approximately 10 years after the introduction of an invasive whitefly, Bemisia tabaci (Genn.) B biotype. Even so the distribution and prevalence of TYLCV remained limited, and the economic damage was minimal.