Publications by authors named "WenFeng Huang"

Introduction: Cardiorenal syndrome (CRS) is a common and critical complication of sepsis, with high morbidity and mortality rates. Studies on biomarkers for the early prediction of septic CRS are sporadic. Classic and novel potential biomarkers were identified to explore their diagnostic performance of in patients with septic CRS.

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Ceftriaxone is widely used in clinical practice for its efficacy against infections. However, its increasing association with life-threatening immune hemolytic reactions urge clinicians to enhance recognition and maintain sharp vigilance. This report details a rare and severe case of ceftriaxone-induced hemolytic anemia (CIHA), hemodynamic instability and hemolytic crisis in a 54-year-old woman after intravenous infusion of ceftriaxone following a respiratory infection.

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Accidental ingestion of lead (Pb)-contaminated soils represents a major route of Pb exposure for both adults and children, and the development of accessible and cost-effective solutions to reduce Pb poisoning is urgently required. Here, we present an effective and straightforward technique, involving the consumption of cola beverages, for the purpose of lowering blood Pb levels following the ingestion of contaminated soils in animal models. This method facilitated the direct passage of Pb in contaminated soil through the digestive system, enhancing its elimination without absorption into systemic circulation.

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The SARS-CoV-2 virus caused the COVID-19 pandemic and brought major challenges to public health. It is transmitted via aerosols, droplets, and fomites. Among these, viral transmission through fomites is not well understood although it remains a very important transmission route.

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  • * Conducted at Peking University People's Hospital, the study measured serum Klotho levels in 349 ACS patients using ELISA tests and collected clinical data.
  • * Findings revealed that serum Klotho levels were significantly higher in acute myocardial infarction (AMI) patients compared to unstable angina (UA) patients and correlated with cardiac function, indicating that elevated Klotho levels could predict poor prognosis in ACS.
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Natural attenuation of organic contaminants can occur under anoxic or oxic conditions. However, the effect of the coupling anoxic-oxic process, which often happens in subsurface soil, on contaminant transformation remains poorly understood. Here, we investigated 2,4-dichlorophenol (2,4-DCP) transformation in Fe-rich soil under anoxic-oxic alternation.

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We present a laser-driven interferometric fiber optic gyroscope (IFOG) with polarization self-compensation to achieve high scale-factor stability, sensitivity, and long-term stability. Coherent light with 200kHz linewidth is employed to keep the scale factor stable. The optical scheme ensures polarization reciprocity as well as the optimal working point for good sensitivity.

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Biochar has been used for soil Cr(VI) remediation in the last decade due to its enriched redox functional groups and good electrochemical properties. However, the role of soil inherent Fe-bearing minerals during the reduction of Cr(VI) has been largely overlooked. In this study, biochar with different electron-donating capacities (EDCs) was produced at 400 °C (BC400) and 700 °C (BC700), and their performance for Cr(VI) reduction in soils with varied properties (e.

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Quantum dense metrology (QDM) performs high-precision measurements by a two-mode entangled state created by an optical parametric amplifier (PA), where one mode is a meter beam and the other is a reference beam. In practical applications, the photon losses of meter beam are unavoidable, resulting in a degradation of the sensitivity. Here, we employ coherent feedback that feeds the reference beam back into the PA by a beam splitter to enhance the sensitivity in a lossy environment.

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Medical images play a vital role in medical analysis by providing crucial information about patients' pathological conditions. However, the quality of these images can be compromised by many factors, such as limited resolution of the instruments, artifacts caused by movements, and the complexity of the scanned areas. As a result, low-resolution (LR) images cannot provide sufficient information for diagnosis.

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  • - The study focused on children with unilateral cerebral palsy (UCP) and their challenges with handwriting, emphasizing the importance of visual-motor integration (VMI) and how conventional assessments may not accurately reflect their performance.
  • - A new computer-aided measure of VMI (CAM-VMI) was developed to objectively assess VMI through geometric shapes and compare the performance of 28 children with UCP to typically-developing peers using both CAM-VMI and the Beery-VMI tests.
  • - Results showed significant differences in VMI performance between the two groups, with the square shape emerging as a key predictor of VMI performance in children with UCP, highlighting its potential role in clinical evaluations.
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  • - The text discusses the importance of secure interaction in wireless sensor networks (WSNs) through protocols that include authentication and key agreement functionalities, addressing vulnerabilities in existing security schemes.
  • - A new security solution is proposed that uses elliptic curve cryptography (ECC) along with biometrics, smart cards, and passwords to create a robust authentication process and secure session key negotiation among users and sensor nodes.
  • - The scheme has been formally validated for security and correctness using established logic and tools, proving its effectiveness against various known attacks, while maintaining efficiency for resource-limited WSNs.
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  • - The study assessed the effectiveness of venetoclax-based regimens in treating acute myeloid leukemia (AML) through a retrospective analysis of 79 patients, focusing on their response rates and survival outcomes.
  • - Among the patients, those with newly diagnosed unfit AML showed a higher complete remission/CR with incomplete hematologic recovery (CR/CRi) rate of 60.5%, compared to 27.8% in relapsed/refractory AML, with specific gene mutations offering significant benefits in the unfit cohort.
  • - The median overall survival for all patients was 9.1 months, with unfit AML patients living significantly longer (14.1 months) than those with relapsed/refractory AML (
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  • The study investigates the effectiveness and safety of the CDCAG regimen (chidamide, decitabine, cytarabine, aclarubicin, and G-CSF) for treating relapsed/refractory acute myeloid leukemia (R/R AML).
  • A total of 67 patients were analyzed, with 65 eligible for response and survival evaluation, revealing a 56.9% complete remission rate and a median overall survival (OS) of 9.6 months.
  • Patients with specific gene mutations showed a higher overall response rate and better OS, suggesting potential benefits from this treatment in the context of allogeneic hematopoietic stem cell transplantation.
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Introduction: Wilt is a soil-borne disease caused by that has become a serious threat to wax gourd production. Disease-resistant graft wax gourds are an effective treatment for wilt. However, there are few reports on the defense mechanism of graft wax gourd against wilt diseases.

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A quantum memory with the performances of low noise, high efficiency, and high bandwidth is of crucial importance for developing practical quantum information technologies. However, the excess noises generated during the highly efficient processing of quantum information inevitably destroy quantum state. Here, we present a quantum memory with built-in excess-noise eraser by integrating a photon-correlated quantum interferometry in quantum memory, where the memory efficiency can be enhanced and the excess noises can be suppressed to the vacuum level via destructive interference.

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  • Phyllosphere microorganisms, which live on plant surfaces, are gaining attention for their diversity and interactions within plant microbiomes, especially in woody and herbaceous plants.
  • The review highlights the lack of comprehensive studies comparing seasonal trends of these microorganisms and aims to explore their dynamic changes and influencing factors throughout the seasons.
  • Factors like climate, insects, and human activities play significant roles in the seasonal variation of phyllosphere microbes, suggesting the need for more extensive research to understand their agricultural applications.
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  • * This study successfully produced metastable CVD Form Ⅱ crystals using a continuous tubular crystallizer, showing it to be an efficient and robust method for crystal generation.
  • * The researchers optimized the crystallization process with air bubbles and ultrasonic irradiation to prevent operational issues, resulting in a new ultrasound-assisted method that improves the production of these pharmaceuticals and tackles encrustation problems.
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Rapid and accurate detection of rare circulating tumor cells (CTCs) in human blood still remains a challenge. We present a surface enhanced Raman spectroscopy (SERS) method based on aptamer-SERS bio-probe recognition coupled with micropore membrane filtration capture for the detection of CTCs at single cell level. The parylene micropore membrane with optimized micropore size installed on a filtration holder could capture bio-probe labeled CTCs by gravity in less than 10 s, and only with very less white blood cells (WBCs) residual.

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  • Gastric cancer (GC) often leads to high mortality rates, primarily due to drug resistance in chemotherapy, making understanding DNA methylation crucial for prognosis and treatment.
  • A study analyzed DNA methylation data alongside survival outcomes to find differential methylation patterns in patients who received chemotherapy versus those who didn't, identifying 308 genes linked to patient prognosis.
  • Six key genes were selected to create a risk model indicating that patients with high-risk scores had shorter survival rates, underscoring the potential of DNA methylation as a predictor for chemotherapy outcomes in GC patients.
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Rationale And Objectives: Fuzi, the dried root of Debx, is one of the widely used traditional Chinese medicines. Fuzi polysaccharides are considered the most bioactive compounds with immunomodulatory functions, however, the mechanisms have not been evaluated. This study aims to systematically investigate the effects of Fuzi polysaccharides on the gut microbiota and immune function using a mouse model immunosuppressed with cyclophosphamide.

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  • Many cancer patients show limited response to immunotherapies, but tumor-infiltrating cytotoxic T lymphocytes (CTL) may boost treatment effectiveness.
  • The study focused on identifying the role of the gene IFI35 in enhancing CD8 T cell activities and its potential benefits for CAR-T cell therapy targeting colorectal cancer.
  • Results indicated that higher IFI35 levels correlate with increased CD8 T cell presence and function, suggesting it could serve as a biomarker to improve CAR-T cell efficacy in colorectal cancer.
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  • * To address this, researchers created interpenetrating polymer network hydrogels using N-isopropylacrylamide (NIPAM) to stabilize the gel and control drug release.
  • * The new KGM/NIPAM gel demonstrated significantly lower release and swelling rates in the stomach and small intestine, indicating its potential for targeted drug delivery to the colon.
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Male sterility is a valuable trait for watermelon breeding, as watermelon hybrids exhibit obvious heterosis. However, the underlying regulatory mechanism is still largely unknown, especially regarding the related non-coding genes. In the present study, approximately 1035 differentially expressed genes (DEGs), as well as 80 DE-lncRNAs and 10 DE-miRNAs, were identified, with the overwhelming majority down-regulated in male-sterile floral buds.

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