Correlation Analysis Between Prognostic Nutritional Index Trajectory Categories and Radiotherapy-induced Severe Oral Mucositis in Head and Neck Cancer Patients Undergoing Radiotherapy.

Purpose: To establish the potential prognostic nutritional index (PNI) trajectory categories and examine the association between these PNI trajectory categories and severe radiotherapy-induced oral mucositis (RIOM).

Materials And Methods: This was a longitudinal retrospective observational study on 470 head and neck cancer inpatients who were to undergo radiotherapy from a grade-A tertiary hospital in Hunan Province between July 2022 and October 2023. The latent class growth model and growth mixed model were used to identify PNI trajectory categories.

Transcriptome Analysis of Rice Near-Isogenic Lines Inoculated with Two Strains of pv. , AH28 and PXO99.

Rice bacterial blight (BB), caused by pv. (), is a major threat to rice production and food security. Exploring new resistance genes and developing varieties with broad-spectrum and high resistance has been a key focus in rice disease resistance research.

Synergistic Effects of Polydopamine/Medical Stone Bio-Adsorbents for Enhanced Interfacial Adsorption and Dynamic Filtration of Bacteria.

Polymer-based wastewater disinfection, which is typically performed using chemical oxidation or irradiation, can result in various toxic byproducts and corrosion under harsh environments. This study introduces a robust bio-adsorbent prepared from naturally abundant polydopamine-modified medical stone (MS@PDA) for the high-efficiency removal of bacteria from water. The PDA nanocoating can be easily applied through an in situ self-polymerization process, resulting in a considerably high bacterial adsorption capacity of 6.

Upper airway hydrodynamics changes after molar distalization with aligners in adult patients.

Objectives: The aim of this study was to evaluate the changes of upper airway ventilation function after molar distalization with aligners in adult patients by computational fluid dynamic simulation.

Materials And Methods: A total of 15 subjects were included (3 males and 12 females, with an average age of 20.00 ± 0.

A nanofibrous polycaprolactone/collagen neural guidance channel filled with sciatic allogeneic schwann cells and platelet-rich plasma for sciatic nerve repair.

Sciatic nerve damage, a common condition affecting approximately 2.8% of the US population, can lead to significant disability due to impaired nerve signal transmission, resulting in loss of sensation and motor function in the lower extremities. In this study, a neural guidance channel was developed by rolling a nanofibrous scaffold produced via electrospinning.

Association of hospital safety climate and compliance with occupational safety practices among nurse interns: A cross-sectional study using canonical correlation analysis.

Background And Aims: Nurse interns may be at a similar or higher risk than registered nurses. The key elements and mechanisms involved in the effects of safety climate on safety performance are not well understood. This study explores the relationship between the perceived hospital safety climate and compliance with occupational safety practices among nurse interns.

NADP-malic Enzyme OsNADP-ME2 Modulates Plant Height Involving in Gibberellin Signaling in Rice.

Plants NADP-malic enzymes (NADP-MEs) act as a class of oxidative decarboxylase to mediate malic acid metabolism in organisms. Despite NADP-MEs have been demonstrated to play pivotal roles in regulating diverse biological processes, the role of NADP-MEs involving in plant growth and development remains rarely known. Here, we characterized the function of rice cytosolic OsNADP-ME2 in regulating plant height.

Relationship evolution shapes inter-brain synchrony in affective sharing: The role of self-expansion.

The development of social relationships influences a person's self-concept, which in turn affects their perceptions and neural correlates in social interactions. This study employed an EEG-based hyperscanning technique and a longitudinal design to investigate how the evolution of interpersonal relationships impacts inter-brain synchrony during nonverbal social-emotional interactions. The framework for this study is based on the self-expansion model.

Microbial communities mediate the effect of cover cropping on soil ecosystem functions under precipitation reduction in an agroecosystem.

Cover cropping is a sustainable agricultural practice that profoundly influences soil microbial communities and ecosystem functions. However, the responses of soil ecosystem functions and microbial communities to cover cropping under the projected changes in precipitation, remain largely unexplored. To address this gap, a field experiment with cover cropping (control, hairy vetch, ryegrass, and hairy vetch plus ryegrass) and precipitation reduction (ambient precipitation and 50 % reduction in ambient precipitation) treatments was conducted from 2018 to 2020 in an agroecosystem located in the Guanzhong Plain of China.

Endosome mediated nucleocytoplasmic trafficking and endomembrane allocation is crucial to polyglutamine toxicity.

Aggregation of aberrant proteins is a common pathological hallmark in neurodegeneration such as polyglutamine (polyQ) and other repeat-expansion diseases. Here through overexpression of ataxin3 C-terminal polyQ expansion in Drosophila gut enterocytes, we generated an intestinal obstruction model of spinocerebellar ataxia type3 (SCA3) and reported a new role of nuclear-associated endosomes (NAEs)-the delivery of polyQ to the nucleoplasm. In this model, accompanied by the prominently increased RAB5-positive NAEs are abundant nucleoplasmic reticulum enriched with polyQ, abnormal nuclear envelope invagination, significantly reduced endoplasmic reticulum, indicating dysfunctional nucleocytoplasmic trafficking and impaired endomembrane organization.

Impulsivity is a stable, measurable, and predictive psychological trait.

Impulsivity is a personality construct frequently employed to explain and predict important human behaviors. Major inconsistencies in its definition and measurement, however, have led some researchers to call for an outright rejection of impulsivity as a psychological construct. We address this highly unsatisfactory state with a large-scale, preregistered study ( = 1,676) in which each participant completed 48 measures of impulsivity derived from 10 self-report scales and 10 behavioral tasks and reported frequencies of seven impulsivity-related behaviors (e.

Perceptions and experience of rural older people in oral health management in China: a qualitative study.

Background: To explore the perceptions and experience of oral health management among rural older people in China.

Methods: Qualitative methodologies were used in this study. Face-to-face semi-structured interviews were conducted.

The role of self-representation in emotional contagion.

Although prior research has implied that emotional contagion occurs automatically and unconsciously, convincing evidence suggests that it is significantly influenced by individuals' perceptions of their relationships with others or with collectives within specific social contexts. This implies a role for self-representation in the process. The present study aimed to offer a novel explanation of the interplay between social contexts and emotional contagion, focusing on the contextualized nature of self-representation and exploring the social factors that shape emotional contagion.

Drosophila models used to simulate human ATP1A1 gene mutations that cause Charcot-Marie-Tooth type 2 disease and refractory seizures.

JOURNAL/nrgr/04.03/01300535-202501000-00034/figure1/v/2024-05-14T021156Z/r/image-tiff Certain amino acids changes in the human Na+/K+-ATPase pump, ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), cause Charcot-Marie-Tooth disease type 2 (CMT2) disease and refractory seizures. To develop in vivo models to study the role of Na+/K+-ATPase in these diseases, we modified the Drosophila gene homolog, Atpα, to mimic the human ATP1A1 gene mutations that cause CMT2.

OsLSC6 Regulates Leaf Sheath Color and Cold Tolerance in Rice Revealed by Metabolite Genome Wide Association Study.

Plant metabolites including anthocyanins play an important role in the growth of plants, as well as in regulating biotic and abiotic stress responses to the environment. Here we report comprehensive profiling of 3315 metabolites and a further metabolic-based genome-wide association study (mGWAS) based on 292,485 SNPs obtained from 311 rice accessions, including 160 wild and 151 cultivars. We identified hundreds of common variants affecting a large number of secondary metabolites with large effects at high throughput.

Improvement of symptoms in children with autism by TOMATIS training: a cross-sectional and longitudinal study.

Introduction: Autism spectrum disorder (ASD) is a neurological condition that is marked by deficits in social interaction, difficulty expressing oneself, lack of enthusiasm, and stereotypical conduct. The TOMATIS training method is an effective music therapy for children with ASD for its individually developed programs to improve behavioral deficits.

Methods: The research employed both longitudinal and crosssectional designs.

Root microbiota analysis of and reveals an orientation selection during the domestication process.

The root-associated microbiota has a close relation to the life activities of plants, and its composition is affected by the rhizospheric environment and plant genotypes. Rice () was domesticated from the ancestor species . Many important agricultural traits and adversity resistance of rice have changed during a long time of natural domestication and artificial selection.

Queen bee gut microbiota extends honeybee lifespan by inhibiting insulin signaling.

Unlabelled: Queen and worker bees are natural models for aging research, as their lifespans vary considerably independent of genetic variation. Investigating the reasons why queens live longer than workers is of great significance for research on the universal processes of aging in animals. The gut microbiome has received attention as a vital regulator of host health, while its precise role in honeybee aging needs further investigation.

Transcription factor encoding gene OsC1 regulates leaf sheath color through anthocyanidin metabolism in Oryza rufipogon and Oryza sativa.

Carbohydrates, proteins, lipids, minerals and vitamins are nutrient substances commonly seen in rice grains, but anthocyanidin, with benefit for plant growth and animal health, exists mainly in the common wild rice but hardly in the cultivated rice. To screen the rice germplasm with high intensity of anthocyanidins and identify the variations, we used metabolomics technique and detected significant different accumulation of anthocyanidins in common wild rice (Oryza rufipogon, with purple leaf sheath) and cultivated rice (Oryza sativa, with green leaf sheath). In this study, we identified and characterized a well-known MYB transcription factor, OsC1, through phenotypic (leaf sheath color) and metabolic (metabolite profiling) genome-wide association studies (pGWAS and mGWAS) in 160 common wild rice (O.

Comparative analysis of locomotor behavior and head diurnal transcriptome regulation by PERIOD and CRY2 in the diamondback moth.

Earth's rotation shapes a 24-h cycle, governing circadian rhythms in organisms. In mammals, the core clock genes, CLOCK and BMAL1, are regulated by PERIODs (PERs) and CRYPTOCHROMEs (CRYs), but their roles remain unclear in the diamondback moth, Plutella xylostella. To explore this, we studied P.

Chickpea: Its Origin, Distribution, Nutrition, Benefits, Breeding, and Symbiotic Relationship with Species.

Chickpea ( L.), encompassing the desi and kabuli varieties, is a beloved pulse crop globally. Its cultivation spans over fifty countries, from the Indian subcontinent and southern Europe to the Middle East, North Africa, the Americas, Australia, and China.

The Trajectory of Oral Mucositis in Head and Neck Cancer Patients Undergoing Radiotherapy and its Influencing Factors.

Background: Oral mucositis (OM) is a common and severe side effect of radiotherapy in head and neck cancer (HNC). The study aimed to investigate the longitudinal changes in OM and its influencing factors in patients with HNC during radiotherapy.

Methods: This was a retrospective longitudinal observational study.

Westerly-triggered lake-effect snowfall enhanced with climate warming over the Tibetan Plateau.

Lake-effect snowfall (LES) occurs when cold air moves across open lakes. LES is expected to occur more frequently over the TP, due to the intensified lake expansion caused by intensified global warming. Thus, there is an urgent need to comprehensively assess the LES over the TP.