Bioabsorbable Fibrillar Gauze Dressing Based on -Carboxyethyl Chitosan Gelling Fibers for Fatal Hemorrhage Control.

Death from lethal hemorrhage remains a major problem in various emergency scenarios. There is a continuous interest in the development of absorbable hemostatic dressings that can control hemorrhage rapidly and can be left in the wound site without removal. In this study, we report a hemostatic gauze dressing based on -carboxyethyl chitosan (CECS) gelling fibers.

Multilineage-differentiating stress-enduring cells alleviate atopic dermatitis-associated behaviors in mice.

Background: Pruritus is a recurring, long-lasting skin disease with few effective treatments. Many patients have unsatisfactory responses to currently available antipruritic treatments, and effective therapeutics are urgently needed to relieve symptoms. A previous study reported that mesenchymal stem cell (MSC)-mediated immune regulation could be used to treat skin inflammatory diseases.

The cellular mechanism by which the rostral ventromedial medulla acts on the spinal cord during chronic pain.

Clinical therapies for chronic pain are limited. While targeted drugs are promising therapies for chronic pain, they exhibit insufficient efficacy and poor targeting. The occurrence of chronic pain partly results from central changes caused by alterations in neurons in the rostral ventromedial medulla (RVM) in the brainstem regulatory pathway.