[Expression of inflammatory cytokines in a mouse model of keratomycosis].

Objective: To investigate the expression, contribution and regulation of predominant inflammatory cytokines in the inflammation process of in a mouse model of keratomycosis.

Methods: It was an experimental study. Two hundred forty inbred BALB/c mice were randomly divided into four groups (injury control group, F.

[Correlations of telomere length changing and pathogeny of keratoconus].

Objective: To study telomere length, senescence-associated-beta-galactosidase (SA-beta-galactosidase) and senescence marker protein-30 (SMP-30) in the stromal cells of keratoconus or normal corneas respectively, aiming finding the association of these indexes with the phenotype of keratoconus.

Methods: Experiment research. 37 keratoconus lesions corneas were removed from 32 keratoconus patients who were operated in Shangdong Eye Institute between January 2006 and December 2006, and 20 normal corneas were collected from eye bank.

[Advance in pathogenesis of fungal keratitis].

Fungal keratitis is the most common and severe infectious corneal diseases in many developing countries. The disease has become the leading cause of corneal blindness in China. It is imperative to study deeply on pathogenesis of fungal keratitis for lowering its incidence, increasing therapeutic option and enhancing therapeutic efficacy.

[Retrospective study of suppurative keratitis in 1054 patients].

Objective: To analyze the etiological and clinical characteristics of 1054 cases with suppurative keratitis.

Methods: Medical records of 1054 inpatients with suppurative keratitis at the Qingdao Eye Hospital, Shandong Eye Institute from January 1999 to December 2004 were retrospectively reviewed for the analysis of demographic features, duration of symptoms, risk factors, previous therapy and laboratory findings.

Results: Fungal keratitis (61.

[Spectrum of infection of fungal keratitis: analysis of 654 cases].

Objective: To investigate the spectrum of infection and epidemiological features of fungal keratitis (FK).

Methods: The demographic data, risk factors, clinical features, laboratory findings, and treatment strategies of 654 patients with FK in Qingdao area, 396 males and 258 females, aged 44.9 +/- 12.