Triazine pyridinium derivative supramolecular cascade assembly extended FRET for two-photon NIR targeted cell imaging.

A triazine pyridinium derivative (TAZpy) was encapsulated into the cavity of a cucurbit[7]uril and further assembled with sulfonatocalix[4]-arene, hyaluronic acid and commercial dyes, which not only achieved fluorescence cascade enhancement and an effective FRET process based on macrocyclic confinement, but was also applied in two-photon NIR targeted cell imaging.

Conformationally confined three-armed supramolecular folding for boosting near-infrared biological imaging.

Herein, a triphenylamine derivative (TP-3PY) possessing 4-(4-bromophenyl)pyridine (PY) as an electron-accepting group and tris[-(4-pyridylvinyl)phenyl]amine (TPA) with large two-photon absorption cross-sections as an electron-donating group was obtained, and showed intense absorption in the visible light region ( = 509 nm) and weak near-infrared (NIR) fluorescence emission at 750 nm. After complexation with cucurbit[8]uril (CB[8]), TP-3PY showed bright NIR fluorescence emission at 727 nm and phosphorescence emission at 800 nm. When the supramolecular assembly (TP-3PY⊂CB[8]) further interacted with dodecyl-modified sulfonatocalix[4]arene (SC4AD), the fluorescence and phosphorescence emissions were further enhanced at 710 and 734 nm, respectively.

Clinicopathological value and underlying molecular mechanism of annexin A2 in 992 cases of thyroid carcinoma.

Background: Thyroid carcinoma (THCA) is one of the most frequent endocrine cancers and has increasing morbidity. Annexin A2 (ANXA2) has been found to be highly expressed in various cancers; however, its expression level and potential mechanism in THCA remain unknown. This study investigated the clinicopathological value and primary molecular machinery of ANXA2 in THCA.

Primitive neuroectodermal tumors of the abdominal wall and vulva in children: Report of two cases and review of the literature.

Background: Primitive neuroectodermal tumors are rare, highly malignant small round cell tumors belonging to the Ewing sarcoma family. The purpose of this article is to present clinical manifestation, histology, treatment, and prognosis of two primitive neuroectodermal tumors (PNETs) in extremely rare anatomic locations, the abdominal wall and vulva.

Case Summary: Case 1 was a 66-month-old girl with lesions on the abdominal wall; tumor size was about 3.

Effects of grafting with pumpkin rootstock on carbohydrate metabolism in cucumber seedlings under Ca(NO3)2 stress.

This study investigated the effects of grafting on the carbohydrate status and the enzymes of carbohydrate metabolism in self-grafted and grafted cucumber seedlings using the salt-tolerant pumpkin rootstock 'Qingzhen 1' (Cucurbita maxima × Cucurbita moschata) under 80 mM Ca(NO3)2 stress for 6 d. The growth of self-grafted seedlings was significantly inhibited after the treatment of Ca(NO3)2 stress, whereas the inhibition of growth was alleviated in pumpkin rootstock-grafted seedlings. Ca(NO3)2 stress increased the contents of the total soluble sugar, sucrose and fructose, but decreased the starch content in rootstock-grafted leaves.

[SDS-PAGE analysis of the antibacterial activity of the hemolymph from housefly larva].

Objective: To study the inducible antibacterial activity of the hemolymph from housefly larva and analyze the antibacterial molecules.

Methods: The hemolymph was collected from the third instar housefly larvae 48 h after pricking treatment. Nine standard bacterial strains were used for determination of the antibaterial activity of the collected hemolymph and its combination with ampicillin.