Publications by authors named "Wen-su Liu"
Behav Brain Res
March 2013
Article Synopsis
- Aluminum, a neurotoxin linked to Alzheimer's disease (AD), was shown to cause brain changes similar to AD, including tau hyperphosphorylation in mice.
- Ginsenoside Rb1, an active component in ginseng, demonstrated neuroprotective effects by improving cognitive function and decreasing tau hyperphosphorylation in mice previously exposed to aluminum.
- The study suggests that Rb1's protective mechanism involves regulation of specific proteins (p-GSK3 and PP2A), positioning it as a potential preventive treatment for Alzheimer's and related neurodegenerative diseases.
