Background: Iliac vein compression syndrome (IVCS) impedes venous blood return from the lower extremities due to iliac vein compression, manifesting as leg swelling, varicose veins, and thrombosis. These symptoms significantly degrade quality of life. Although iliac vein stenting provides symptomatic relief, the recovery process is protracted and fraught with challenges such as in-stent restenosis and psychological distress.
View Article and Find Full Text PDFBackground: Intraoperative radiotherapy (IORT) is a convenient treatment techniques for patients with early-stage breast cancer. We aimed to compare the outcome of IORT to that of whole-breast external beam radiotherapy (EBRT) in highly selected breast cancer patients based on the 2023 American Society for Radiation Oncology (ASTRO) Clinical Practice Guideline for Partial Breast Irradiation (PBI).
Patients And Methods: We reviewed patients who underwent breast-conserving surgery (BCS) and received either IORT or EBRT for early-stage breast cancer between 2014 and 2019.
A fire and explosion accident at a petrochemical complex sparked concerns over the rice health and production in nearby paddy fields. To unveil the potential effects, this study investigated small molecule changes in rice harvested in nearby counties using non-target analysis. Rice grains were harvested three, eight, 15, and 20 months after the accident from a total of ten townships.
View Article and Find Full Text PDFBackground: Chronotropic incompetence (CI) severely limits exercise tolerance due to impaired heart rate responses. This study investigated whether pacemaker with closed-loop stimulation (DDD-CLS) pacing, which provides rate acceleration in response to exertion, could enhance lung function and cardiopulmonary capacity compared pacemaker without CLS pacing in patients with CI.
Methods: This randomized crossover trial included 32 patients with CI who were compared to each CLS and DDD pacing over 2 months.
Most cancer cells reprogram their glucose metabolic pathway from oxidative phosphorylation to aerobic glycolysis for energy production. By reducing enzyme activity of pyruvate kinase M2 (PKM2), cancer cells attain a greater fraction of glycolytic metabolites for macromolecule synthesis needed for rapid proliferation. Here we demonstrate that hydrogen sulfide (HS) destabilizes the PKM2 tetramer into monomer/dimer through sulfhydration at cysteines, notably at C326, leading to reduced PKM2 enzyme activity and increased PKM2-mediated transcriptional activation.
View Article and Find Full Text PDFObjectives: The purpose of this research was to assess the effect of telehealth management via WeChat on improving the quality of life of patients after percutaneous coronary intervention (PCI).
Methods: In this study, we retrospectively collected the clinical data of 118 patients who underwent PCI and received remote health management from our hospital via WeChat from June 2021 to September 2021 (WeChat group). The clinical data of 114 patients who underwent PCI but did not receive remote health management from our hospital from September 2020 to December 2020 were also collected (conventional group).
Since traditional photocatalysts have suffered from higher charge carrier recombination and moderate photocatalytic efficiency, developing photocatalysts is crucial for water treatment objectives. Hence, the various ratios of TiO on g-CN (CN) to form nano photocatalysts were synthesized by the solvothermal method. The 30%TiO/CN showed the best performance to degradation and debromination of 4-bromophenol (4-BP) solution completely (k = 6.
View Article and Find Full Text PDFOpen reduction with internal fixation is a common approach for treating distal radius fractures. However, complications such as extensor tendon rupture can occur following this procedure. In this case report, we present a patient who experienced extensor tendon rupture following volar plate fixation of a distal radius fracture.
View Article and Find Full Text PDFNatural organic matter is a mixture of microbial decomposition products widely found in surface and groundwater. These organic materials have great potential as carbon-based precursors for chemical synthesis. This work demonstrated the development of a green photocatalyst via a facile adsorption process that combined colloidal titanium dioxide (TiO) with humic acid.
View Article and Find Full Text PDFAims: This study aimed to investigate the effectiveness of closed-loop stimulation (CLS) pacing compared with the traditional DDD mode in patients with chronotropic incompetence (CI) using bicycle-based cardiopulmonary exercise testing (CPET).
Methods And Results: This single-centre, randomized crossover trial involved 40 patients with CI. Patients were randomized to receive either DDD-CLS or DDD mode pacing for 2 months, followed by a crossover to the alternative mode for an additional 2 months.
Important concepts in leadership management related to the field of medical care management include servant leadership, charismatic leadership, and transformational leadership. Since the 2020 emergence of the coronavirus pandemic, the world has faced the immediate challenges of epidemic prevention and control. Although national government and medical system officials as well as scholars have weighed in on this issue, their leadership does not appear to line up the core ideas of leadership.
View Article and Find Full Text PDFLivestock wastewater has been reused for agricultural irrigation to save water and fertilise the soil. However, micropollutants excreted by livestock animals may contaminate the soil and crops through livestock wastewater irrigation. This study employed high-resolution mass spectrometry (HRMS) to facilitate broad-scope suspect screening of soil and vegetables and identify changes in micropollutant fingerprints caused by swine wastewater irrigation.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
October 2022
Non-alcoholic fatty liver disease(NAFLD), as a metabolic stress liver injury disease, is one of the most common chronic liver diseases, which seriously threatens people's health. The pathogenesis of NAFLD is very complex. A large number of studies show that the hepatic mitochondrial dysfunction leads to the disorder of hepatic glucose and lipid metabolism, oxidative stress, and inflammation, thus inducing hepatocyte apoptosis, which plays an important role in the progression of NAFLD.
View Article and Find Full Text PDFEnviron Sci Eur
October 2022
Background: The NORMAN Association (https://www.norman-network.com/) initiated the NORMAN Suspect List Exchange (NORMAN-SLE; https://www.
View Article and Find Full Text PDFObjective: This study aims to determine the factors associated with patient care manager role and the implementation of the clinical pathway among nurses in private hospitals.
Methods: This study was conducted from January-July 2021 using the cross-sectional approach. The sample consisted of 168 nurses working in a private hospital in Surabaya City, East Java, Indonesia.
Mislabelling the geographic origin of same-species aquaculture products is difficult to identify. This study applied untargeted small-molecule fingerprinting to discriminating between Atlantic salmon originating from Chile and Norway. The acquired liquid chromatography-high-resolution mass spectrometry data from Chilean (n = 32) and Norwegian (n = 29) salmon were chemometrically processed.
View Article and Find Full Text PDFHexabromocyclododecanes (HBCDs) are globally prevalent and persistent organic pollutants (POPs) listed by the Stockholm Convention in 2013. They have been detected in many environmental media from waterbodies to Plantae and even in the human body. Due to their highly bioaccumulative characterization, they pose an urgent public health issue.
View Article and Find Full Text PDFDeveloping highly sensitive and selective methods for Cu detection in living systems is of great significance in clinical copper-related disease diagnosis. In this work, a near infrared (NIR) fluorescent probe, CySBH, with a salicylaldehyde benzoyl hydrazone group as a selective and sensitive receptor for Cu was designed and synthesized. The specific coordination of the salicylaldehyde benzoyl hydrazone group in CySBH with Cu can induce a distinct quench of the fluorescence intensity, allowing for real-time tracking of Cu.
View Article and Find Full Text PDFThe accumulation of β-sheet-rich α-synuclein (α-Syn) protein in human brain cells is a pathological hallmark of Parkinson's disease (PD). Moreover, it has been reported that familial PD mutations (A30P, E46K, H50Q, G51D, and A53T) accumulate at an accelerated rate both in vivo and in vitro. In addition, accumulations of various C-terminal α-Syn truncations, such as C-terminal-truncated N103 α-synuclein (N103), were found in an aggregated form in the brain tissue of PD patients.
View Article and Find Full Text PDFSulfamethoxazole (SMX) is largely prescribed for bacterial infections but raises a major concern over generation of antibiotic-resistant bacteria in the environment. This study employed various perovskite-type photocatalysts, made by two-step synthesis procedures, to remove SMX. The as-synthesized CaCuTiO (CCTO) perovskites were characterized by XRD, SEM-EDX, and DLS.
View Article and Find Full Text PDFNeutrophils are the primary immune cells in innate immunity, which are related to various inflammatory diseases. is a Chinese medicinal herb used to treat various oxidative stress-related inflammatory diseases. However, there are limited studies that elucidate the effects of in human neutrophils.
View Article and Find Full Text PDFThe use of livestock waste for the production of biogas and the application of biogas slurry to agricultural soil can resolve livestock waste problems and reduce synthetic fertiliser use. However, the migration of veterinary drugs to land and crops resulting from biogas slurry irrigation is a potential food safety concern. This study employed an ultra-performance liquid chromatography coupled with quadrupole-time of flight high-resolution mass spectrometry system for wide-scope suspect screening of pharmaceutically active substances on crop cultivated under biogas slurry irrigation.
View Article and Find Full Text PDFPolymeric oxygen rich exfoliated graphitic carbon nitride (exfoliated GCN, EGCN) was synthesized by the acid treatment of bulk GCN. The photocatalyst was characterized using X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, and point of zero charge. EGCN shows high valance band hole transfer under short-time visible light (λ > 420 nm) exposure for photocatalytic mineralization of bisphenol A (BPA).
View Article and Find Full Text PDFPsychiatric ward (PW) nurses are at a higher risk to encounter workplace violence than are other healthcare providers, and many interventions have been developed to improve their mental health. We compared the effectiveness of biofeedback training (BT) and smartphone-delivered BT (SDBT) interventions on occupational stress, depressive symptoms, resilience, heart rate variability, and respiration rate in a sample of abused PW nurses. This was a quasi-experimental study.
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