[Spatiotemporal Differentiation and Degradation Analysis of Polybrominated Diphenyl Ethers in Sediments of Shanmei Reservoir and Its Inflowing River, Quanzhou, China].

To investigate the spatiotemporal differentiation of polybrominated diphenyl ethers (PBDEs) in urban water-source reservoirs and degradation sources of BDE homologues and their contributions, we analyzed the contents, pollution degrees, spatial distributions, hydrological period changes, inventories, profiles, and degradation source contributions of PBDEs in the surface sediments of Shanmei Reservoir and its inflowing river, Quanzhou, China. The results showed that the median ∑PBDEs (1072.1 ng ·g) in the inflowing river sediment was 6.

[Indoor Deposition Flux, Seasonal Variations and Human Exposure Levels of Polybrominated Diphenyl Ethers in Xiamen, China].

Indoor dust was an important and even a major route of human exposure to polybrominated diphenyl ethers (PBDEs). However, the vacuum dust concentrations were less correlated with indoor residents' serum concentrations of PBDEs, thus inadequat for either estimation of human exposure dose or research of deposition flux and its seasonal variations. Passive sampling of indoo dustfall could offset these shortages.

[Indoor deposition flux and congener profiles of polybrominated diphenyl ethers (PBDEs) in Shanghai, China].

Indoor dry deposition of eight homes and offices in the urban area of Shanghai, China were sampled with clean glass plate during July to August of 2008 to study the indoor deposition flux and congener profiles of polybrominated diphenyl ethers (PBDEs). 16 PBDEs congeners which including BDE-17, -28, -71, 47, -66, -77, -100, -99, -85, -118, -154, -153, -138, -183, -190 and BDE-209 were measured by GC-MS with negative chemical ionization (NCI) in selected ion monitoring (SIM) mode. The particulate deposition flux of PBDEs in homes and offices were (10.

[Expression of cyclooxygenase-2 and relationship with mismatch repair gene and microsatellite instability in hereditary non-polyposis colorectal cancer].

Objective: To investigate the expression of Cyclooxygenase (COX)-2 and the relationship between cox-2, mismatch repair gene (MMR) proteins and microsatellite instability (MSI) in HNPCC.

Methods: Twenty-eight cases of adenomas and 14 cases of carcinomas were collected from 33 HNPCC families patients by colonoscopy. Sporadic adenomas (n = 32) and carcinomas (n = 24) were used as a control group.

[Mutation of hMLH1 and hMSH2 genes in hereditary nonpolyposis colorectal cancer: analysis of 76 probands].

Objective: To investigate the mutations of the mismatch repair genes hMLH1 and hMSH2 in hereditary nonpolyposis colorectal cancer (HNPCC).

Methods: The DNA samples of 76 probands of HNPCC families underwent PCR amplification and sequencing on 35 exons in hMLH1 and hMSH2 genes.

Results: (1) The overall mutation rate of the hMLH1 and hMSH2 genes was 33% (25/76).