Proteomics analyses of acute kidney injury biomarkers in a rat exertional heat stroke model.

The frequency of exertional heat stroke (EHS) increases with the gradual elevation of global temperatures during summer. Acute kidney injury (AKI) is a common complication of EHS, and its occurrence often indicates the worsening of a patient's condition or a poor prognosis. In this study, a rat model of AKI caused by EHS was established, and the reliability of the model was evaluated by HE staining and biochemical assays.

Impacts of Mercury Exposure Levels and Sources on the Demethylation of Methylmercury Through Human Gut Microbiota.

This study aims to investigate methylmercury (MeHg) demethylation processes in human gut. Here, we determined the compositions and MeHg demethylation rates of gut microbiota in residents from different Hg exposure levels (Wanshan (WS) town and Yangtou (YT) town) and different Hg exposure sources (Zhuchang (ZC) town and YT town) regions. MeHg and inorganic Hg exposure levels in residents of WS town were significantly higher than those of YT and ZC town.

Revealing Potential Diagnostic Gene Biomarkers Associated with Immune Infiltration in Patients with Renal Fibrosis Based on Machine Learning Analysis.

Chronic kidney disease is characterized by the development of renal fibrosis. The basic mechanisms of renal fibrosis have not yet been fully investigated despite significant progress in understanding the etiology of the disease. In this work, the researchers sought to identify potential diagnostic indicators for renal fibrosis.

Two New C19-Diterpenoid Alkaloids from Aconitum nagarum var. lasiandrum.

Continuous investigations of the roots of Aconitum nagarum var. lasiandrum led to the isolation of two new C₁₉-diterpenoid alkaloids, lasiandrine (1) and lasiandroline (2). Their structures were elucidated on the basis of extensive interpretation of spectroscopic and mass spectrometric data.

Blood pressure change during phacoemulsification and femtosecond laser-assisted cataract surgery.

Aim: To evaluate blood pressure (BP) changes during phacoemulsification (PC) and femtosecond laser (FSL)-assisted cataract surgery.

Methods: A retrospective chart review was performed for all patients who received traditional phacoemulsification surgery (PC group) and FSL-assisted cataract surgery (FS group) from July 2013 to December 2014. Totally 206 eyes from 133 patients receiving the two types of procedures were included.

Neuroanatomical differences between men and women in help-seeking coping strategy.

Help seeking (HS) is a core coping strategy that is directed towards obtaining support, advice, or assistance as means of managing stress. Women have been found to use more HS than men. Neural correlates of sex differences have also been reported in prefrontal-limbic system (PLS) regions that are linked to stress and coping, yet structural differences between men and women relating to HS in the PLS are still unknown.

A voxel-based morphometry study of regional gray and white matter correlate of self-disclosure.

Self-disclosure is an important performance in human social communication. Generally, an individual is likely to have a good physical and mental health if he is prone to self-disclosure under stressful life events. However, as for now, little is known about the neural structure associated with self-disclosure.

The correlation between gray matter volume and perceived social support: a voxel-based morphometry study.

Social support refers to interpersonal exchanges that include the combinations of aid, affirmation and affection. Perceived social support is a kind of subjective judgment of one's availability of social support. In spite of the importance of perceived social support to health, however, its neural substrate remains unknown.

The time course of breaking mental sets and forming novel associations in insight-like problem solving: an ERP investigation.

In the present study, high-density event-related potentials were recorded to examine the electrophysiological correlates of logogriph problem solving in using a new experimental paradigm (learning-testing model) that was adopted in order to enable subjects to find a solution on their own initiative. For each trial, subjects were given a target logogriph followed by three types of base logogriphs: surface similarity logogriphs (SUSL, the base logogriph and target logogriph share some same words), structural similarity logogriphs (STSL, the base and target logogriphs do not have any words in common), and baseline logogriphs (BSL, the base and target logogriphs are all simple character-generation tasks). The results demonstrated a more negative event-related potential deflection during STSL than during SUSL in both the 300-500 and 1,100-1,300 ms time windows, most likely reflecting the breaking of mental sets during insight-like problem solving.

[Grassland net primary productivity and its spatiotemporal distribution in northern Tibet: a study with CASA model].

Based on the remote sensing data, meteorological data and other related data from 1981 to 2004, the grassland net primary productivity (NPP) and its spatiotemporal distribution in Northern Tibet were analyzed by CASA (Carnegie-Ames-Stanford Approach) model. The results indicated that in the study area, the spatial distribution of grassland NPP was affected by the local water and heat conditions, and represented a horizontal zonality. From southeast to northwest, the grassland NPP reduced from 230 g C x m(-2) x a(-1) to near 0 g C x m(-2) x a(-1).