Low back pain in China: Disease burden and bibliometric analysis.

Background: Low back pain has become a global problem. Since many traditional Chinese therapies are helpful for low back pain, the current status of low back pain in China may provide some insights to this issue.

Aim: To demonstrate the disease burden of low back pain in China and the response of Chinese scholars to this issue.

Non-pyrolytic synthesis of laccase-like iron based single-atom nanozymes for highly efficient dual-mode colorimetric and fluorescence detection of epinephrine.

Single-atom nanozymes have garnered significant attention due to their exceptional atom utilization and ability to establish well-defined structure-activity relationships. However, conventional pyrolytic synthesis methods pose challenges such as high energy consumption and random local environments at the active sites, while achieving non-pyrolytic synthesis of single-atom nanozymes remains a formidable technical hurdle. The present study focuses on the synthesis of laccase-like iron-based single-atom nanozymes (Fe-SAzymes) using a non-pyrolysis method facilitated by microwave irradiation.

Colorimetric sensor array for identifying antioxidants based on pyrolysis-free synthesis of Fe-N/C single-atom nanozymes.

Iron-anchored nitrogen/doped carbon single-atom nanozymes (Fe-N/C), which possess homogeneous active sites and adjustable catalytic environment, represent an exemplary model for investigating the structure-function relationship and catalytic activity. However, the development of pyrolysis-free synthesis technique for Fe-N/C with adjustable enzyme-mimicking activity still presents a significant challenge. Herein, Fe-N/C anchored three carrier morphologies were created via a pyrolysis-free approach by covalent organic polymers.

MAMs and Mitochondrial Quality Control: Overview and Their Role in Alzheimer's Disease.

Alzheimer's disease (AD) represents the most widespread neurodegenerative disorder, distinguished by a gradual onset and slow progression, presenting a substantial challenge to global public health. The mitochondrial-associated membrane (MAMs) functions as a crucial center for signal transduction and material transport between mitochondria and the endoplasmic reticulum, playing a pivotal role in various pathological mechanisms of AD. The dysregulation of mitochondrial quality control systems is considered a fundamental factor in the development of AD, leading to mitochondrial dysfunction and subsequent neurodegenerative events.

Impact of solar ultraviolet radiation on daily outpatient visits of atopic dermatitis in Shanghai, China.

The potential roles of solar ultraviolet radiation (UVR) as an environmental risk factor in inducing atopic dermatitis (AD) have not been well quantified. To determine the short-term associations between UVR and AD outpatient visits, we obtained daily outpatient visits of AD in Shanghai Skin Disease Hospital from 2013 to 2018. Data of hourly ground UVR were collected.

Cutaneous vessel features of sensitive skin and its underlying functions.

Background: Following the sufficient studies of the effects of skin barrier impairment and heightened neural reaction on sensitive skin (SS), many scholars have paid great attention to the roles of superficial microvasculature in SS.

Methods: By questionnaire survey, lactic acid sting test, and capsaicin test, eligible subjects were classified as normal skin, only lactic acid sting test positive (LASTP), only capsaicin test positive (CATP), and both positive (both LASTP and CATP). D-OCT was used to photograph images for evaluating the cutaneous vessels features each group.

[Effects of training of human intestinal parasitic diseases for basic health staff in Jiangsu Province].

Objective: To evaluate the effect of the training of human intestinal parasitic diseases for basic health staff.

Methods: A workshop including theory courses and practical operations was carried out. At the end of the workshop, the effects were evaluated through the examinations of theory and film-reading.

[Prediction of hookworm incidence with time-series model in Jiangsu Province].

Objective: To explore the feasibility of autoregressive integrated moving average (ARIMA) to predict the infection rates of hookworm in Jiangsu Province.

Methods: From 1990 to 2006, the infection rates of hookworm were used for a training data set. As to obtain a stationary data set, the training data set was second-order differenced using the version SAS 9.

[Surveillance of soil-transmitted nematodiasis in northern Jiangsu Province from 2006 to 2010].

Objective: To evaluate the control effect on soil-transmitted nematodiasis in surveillance sites of northern Jiangsu Province.

Methods: According to "The Monitoring Program on Soil-transmitted Nematodiasis in Jiangsu Province", the eggs of soil-transmitted nematodes were detected by the Kato-Katz technique and cellophane anal swab technique, and the infection rates were predicted by the horizontal average speed development method in the surveillance sites from 2006 to 2010.

Results: The overall infection rate of soil-transmitted nematodes declined to 3.

[Comparison between two expression ways on cysteine protease of Clonorchis sinensis].

Objective: To compare the prokaryotic expression system and eukaryotic expression system for the expression of cysteine protease of Clonorchis sinensis, and the diagnostic efficiency of their objective products.

Methods: According to the sequence of cysteine protease of C. sinensis, two pairs of primers were designed to amplify the genes from the total cDNA of C.

[Cloning, expression and evaluation on effect in serological diagnosis of cysteine protease of Clonorchis sinensis].

Objective: To clone and express the cysteine protease of Clonorchis sinensis and evaluate its effect on immunodiagnosis of human clonorchiasis.

Methods: Based on a cysteine protease gene fragment of C. sinensis (CS-CP, GenBank accession: AF093242), a pair of primers were designed and amplified from total cDNA of C.

[Preliminary study on detection of Echinococcus granulosus DNA by loop-mediated isothermal amplification].

Objective: To evaluate the sensitivity of loop-mediated isothermal amplification (LAMP) on the detection of Echinococcus granulosus.

Methods: The DNAs were extracted from Echinococcus granulosus eggs and adults. According to Echinococcus mitochondrial 12S rRNA sequences and the mechanism of LAMP, 4 Echinococcus specific primers were designed and used for LAMP assay, and Bubble taenia and the blank were used as the negative control for evaluation of the specificity.

[Performance evaluation of rural latrine renovation in key schistosomiasis control areas, Jiangsu Province].

Objective: To evaluate the hygienic, environmental, social and economic benefits achieved by rural latrine renovation in key schistosomiasis control areas, Jiangsu Province.

Methods: Eights villages (evaluation villages) that finished and the three villages (control villages) that did not finish the latrine renovation work were sampled and investigated through field visits, questionnaire, referring to information and so on, to collect relevant data, and human waste samples were detected for laboratory indicators in hygiene and environment, in key schistosomiasis control areas in three counties (cities, districts), Jiangsu Province.

Results: A total of 11 villages and 220 households were investigated.

[Purification of Clonorchis sinensis native protein and their application in immunodiagnosis of clonorchiasis].

Lots of purified antigens have been obtained from crude antigens of Clonorchis sinensis. Some of them have applied to immunodiagnosis of clonorchiasis in laboratory. Here, we review purification methods, diagnostic efficacy and application prospect of purified antigens.

[Process for lymphatic filariasis elimination in Jiangsu Province, China].

Objective: To review the process of lymphatic filariasis elimination in Jiangsu Province, and summarize the control experience.

Methods: The data of epidemic status, control and surveillance of lymphatic filariasis were collected and analyzed in Jiangsu Province from 1950s to 1990s.

Results: Lymphatic filariasis was endemic in 71 counties (cities) among all 75 counties (cities) in Jiangsu Province.

[Epidemic situation and control of soil-transmitted nematodiasis in Jiangsu Province].

Objective: To analyze the prevalence changes and the control measures of soil-transmitted nematodiases in Jiangsu Province in the recent 20 years and evaluate the control effect, so as to explore the control strategies and measures appropriate to current epidemic characteristics.

Methods: The data on surveillance, control measures and control effect of soil-transmitted nematodiases in Jiangsu Province from 1990 to 2009 were collected and analyzed.

Results: Different control programs were taken in different control stages in Jiangsu Province.