[Role of remodeling of pharyngeal cavity in velopharyngoplasty for treating obstructive sleep apnea hypopnea syndrome and its related anatomic study].

Objective: To investigate a new velopharyngoplasty (VPP), including its anatomic character and its mechanism of remodeling of oral-pharynx cavity for treating obstructive sleep apnea hypopnea syndrome (OSAHS).

Methods: Two cases of soft palate were dissected in adult male cadavers. And the model of VPP was established to further observe its technical characteristics.

[Neuroprotective effects of learning on glutamate-induced neuronal damage in rat hippocampus].

Aim: To investigate the neuroprotective effect of learning on glutamate-induced neuronal damage.

Methods: SD rats were intraperitoneally injected with monosodium glutamate (MSG) during the period of 3-9 days after born, and were trained to find their food by light-dark discrimination at 1 month old or 2 months old. At 3 months old, all rats were killed and their brains were taken out and cut into sections and ultrathin sections.

[Interleukin-5 regulate the bone marrow response in the model of allergic rhinitis].

Objective: To elucidate the mechanism of bone marrow response regulated by interleukin-5 (IL-5) in the model of allergic rhinitis.

Methods: Twenty SD rats were randomly divided into allergic rhinitis (AR) group and control group. The leucocytes in the smears of bone marrow and peripheral blood were counted, and the expression of IL-5 was detected by immunohistochemistry.

[A study of the link between upper and lower respiratory inflammation].

Objective: To evaluate the correlation between upper and lower respiratory inflammation.

Methods: Thirty rats were randomly divided into allergic rhinitis group (AR), asthma group (AS), and control group (Con). The pulmonary function was measured by pulmonary function instrument of animal model, the infiltration of eosinophils and mast cells was detected by hematotoxylin-eosin staining (HE staining) and toluidine blue staining respectively, the expression of VCAM-I and IL-13 was examined by immunohistochemistry.