Publications by authors named "Wen-Zheng Wu"
Article Synopsis
- Environmental stressors, like cadmium (Cd), significantly contribute to acute kidney injury (AKI) by inducing ferroptosis in renal cells.
- Exposure to Cd disrupts the arachidonic acid metabolic pathway and increases harmful lipid peroxidation markers in mice kidneys, indicating oxidative stress.
- Reduced levels of SIRT3 lead to increased acetylation of GPX4, exacerbating ferroptosis, but treatment with nicotinamide mononucleotide (NMN) helps mitigate these effects.
