Publications by authors named "Wen-Zhen Ding"

Background: The range of an ablation zone (AZ) plays a crucial role in the treatment effect of microwave ablation (MWA). The aim of this study was to analyze the factors influencing the AZ range.

Methods: Fourteen factors in four areas were included: patient-related factors (sex, age), disease-related factors (tumor location, liver cirrhosis), serological factors (ALT, AST, total protein, albumin, total bilirubin, direct bilirubin, and platelets), and MWA parameters (ablation time, power, and needle type).

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Article Synopsis
  • The study investigates local tumor progression (LTP) post-thermal ablation of liver tumors, questioning if all LTP cases are due to imperfect ablation, with a focus on the shortest ablation margin (AM) in the ablation zone (AZ).
  • Analysis included 185 LTP incidents, utilizing visual assessments and 3D tumor mapping to determine relationships between LTP occurrence and the shortest AM quadrant, revealing patterns in progression types over time.
  • Results suggest most LTPs cluster in the shortest AM quadrant, while certain types, like dissociated LTPs that occur beyond 24 months, may not be related to ablation flaws, indicating a need for further research in treatment outcomes
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Objective: To develop and validate an ultrasonic radiomics model for predicting the recurrence and differentiation of hepatocellular carcinoma (HCC). Convolutional neural network (CNN) ResNet 18 and Pyradiomics were used to analyze gray-scale-ultrasonic images to predict the prognosis and degree of differentiation of HCC.

Methods: This retrospective study enrolled 513 patients with HCC who underwent preoperative grayscale-ultrasonic imaging, and their clinical characteristics were observed.

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