Publications by authors named "Wen-Zhang zha"

Background: Endoscopic and laparoscopic techniques are crucial for management of bile duct stone.

Objective: The aim of this study was to share our initial experiences with endoscopic and laparoscopic treatments for recurrent choledocholithiasis, with a particular focus on long-term complications.

Methods: From January 2014 to June 2017, a total of 153 patients with recurrent common bile duct stones were prospectively recruited in this study.

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Background: Incidental gall bladder cancer (IGBC) is often discovered unexpectedly in patients after cholecystectomy. Currently, magnetic resonance imaging (MRI) has been widely applied in the pre-operative diagnosis of gall bladder diseases as laparoscopic cholecystectomy developed into the preferred method.

Aims And Objectives: This study aimed to evaluate the pre-operative MRI application and laparoscopic management in the IGBCs.

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Objective: This study aimed to assess the safety and efficacy of left liver anatomical resection via the left vertical groove following intraoperative antegrade cholangioscopy (biliary exploration through the left hepatic duct orifice) in patients with left-sided hepatolithiasis (LSH) and previous biliary tract surgery.

Methods: Between January 2012 and January 2016, eligible patients with LSH (n = 28) who underwent left liver anatomical resection via the left vertical groove followed by intraoperative antegrade cholangioscopy, were referred to our hospital. Clinical results, such as the overall operative time, length of hospital stay, intraoperative complications, residual stones and postoperative bile leaks, were recorded and analyzed.

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Background: Hepatocellular carcinoma (HCC) is one of the main causes of cancer-related death. This study aims to explore the role and underlying mechanism of H19 in HCC.

Methods: qRT-PCR detected miR-15b-5p and H19 expression, as well as the mRNA level of EMT-associated genes.

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Background: there is an increasing incidence rate of cholecysto-choledocholithiasis associated with the increasing proportion of senile individuals.

Methods: a total of 100 elderly patients (over 80 years of age) suffering both from cholelithiasis and choledocholithiasis were retrospectively studied from January 2010 to December 2016. Patients were scheduled for either a single-stage or two-stage procedure.

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Article Synopsis
  • The study investigates treatment methods for left-sided hepatolithiasis (LSH), comparing two approaches: intraoperative biliary exploration via the left hepatic duct (LHD) and the common bile duct (CBD).
  • Results show that patients in the LHD group experienced fewer complications, shorter operative times, and reduced hospital stays compared to those in the CBD group, with no residual stones found in either group.
  • The conclusion suggests that LHD cholangioscopy is a more effective technique for LSH patients with previous biliary surgeries, enhancing efficiency and minimizing risks.
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 Choledocholithiasis can be managed by transcystic (TC) and transduct (TD) stone extraction or using cholangioscopy through the left hepatic duct orifice (LHD).  The aim of this study is to evaluate the safety and effectiveness of common bile duct exploration through the TC approach, TD approach, and LHD approach for choledocholithiasis, with a specific emphasis on the TC and LHD approaches versus the TD approach.  Between January 2011 and June 2014, a total of 172 choledocholithiasis patients accompanied by cholecystitis and/or left intrahepatic gallstones were scheduled for laparoscopic or open common bile duct (CBD) exploration using cholangioscopy through the CBD (TD group: n = 72), cystic duct (TC group: n = 63), or LHD orifice (LHD group: n = 37).

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Article Synopsis
  • The study compares the safety and effectiveness of three methods for extracting common bile duct stones in patients with choledocholithiasis: ERCP/EST, transcystic (TC) approach, and transductal (TD) approach.
  • Results showed that the TD approach had a 100% bile duct clearance rate, while the TC and ERCP groups had slightly lower rates (93.7% and 92.3% respectively), but the TD method also resulted in more postoperative complications, specifically bile leaks.
  • The TD group experienced longer hospital stays and higher morbidity compared to TC and ERCP groups, with significant complications including duodenal perforations in the ERCP group leading to one
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Objectives: The clinical presentation of myocarditis often mimics acute coronary syndrome. Coronary sinus flow has been used for detection of the presence of myocardial ischemia. Whether myocarditis is associated with changes in coronary sinus flow remains unknown.

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Article Synopsis
  • A patient diagnosed with rectal polyps sought surgical treatment at a different hospital after an abdominal CT revealed a large irregular tumor near the lower rectal wall.
  • During surgery, a sizable tumor was found and an anterior resection with end colostomy (Hartmann's procedure) was performed.
  • Post-surgery, histological tests revealed that the patient had both gastrointestinal stromal tumor (GIST) and rectal polyps occurring simultaneously.
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Background: The aim of this study is to evaluate the safety and feasibility of laparoscopic common bile duct exploration and primary closure of choledochotomy for the patients with common bile duct stones (CBDS) who failed in endoscopic sphincterotomy (EST).

Methods: Between January 2007 and June 2012, a total of 78 patients who subjected to endoscopic retrograde cholangiopancreatography (ERCP) and EST, but failed in endoscopic stone extraction, were referred to us. The following day, laparoscopic cholecystectomy, laparoscopic common bile duct exploration (LCBDE) and primary closure of choledochotomy were performed in all patients.

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