Publications by authors named "Wen-Yue Lin"
Highly spatiotemporal-resolved photomodulation demonstrates promise for investigating key biological events in vivo and in vitro, such as cell signaling pathways, neuromodulation, and tumor treatment without side effects. However, enhancing the performance of photomodulation tools remains challenging due to the limitations of the physicochemical properties of the photoactive molecules. Here, a compact, stable intramolecular π-π stacking conformation forming between the target molecule (naproxen) and the perylene-based photoremovable protecting group is discovered to confine the motion of the photolabile bond and then enhance the photocleavage quantum yield.
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- - The study addresses the challenges in detecting disease biomarkers due to issues like autofluorescence in biological samples, proposing a new method using self-assembled natural proteins for improved biosensing.
- - Researchers created a novel nanoprobe, a photon upconversion supramolecular assembly (PUSA), which is small, biocompatible, and can effectively detect urinary sarcosine, a biomarker for prostate cancer, under near-infrared light.
- - This innovative approach not only enables easy visual identification of prostate cancer markers in urine samples but also allows for accurate quantification, marking significant progress in clinical diagnostics for malignant diseases.
Oxygen-mediated triplet-triplet annihilation upconversion (TTA-UC) quenching limits the application of such organic upconversion materials. Here, we report that the photooxidation of organic amines is an effective and versatile strategy to suppress oxygen-mediated upconversion quenching in both organic solvents and aqueous solutions. The strategy is based on the dual role of organic amines in photooxidation, i.
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