Publications by authors named "Wen-Wen Chu"

Background: Higher β2-Microglobulin (β2-MG) is associated with aging, stroke and cognitive impairment, which are all connected with poor physical fitness. Poor physical function is ascribed to increasing mortality. However, there has been an academic dispute over the association of serum β2-MG with survival rate.

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Objectives: This study describes the detection and tracking of emergency neurosurgical cross-transmission infections with carbapenem-resistant (CRKO).

Methods: We conducted an epidemiological investigation and a rapid screening of 66 surveillance samples using the chromogenic selective medium. Two CRKO isolates from infected patients and three from the preoperative shaving razors had similar resistance profiles identified by the clinical laboratory.

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Objective: Peritoneal fibrosis (PF) is the main cause of declining efficiency and ultrafiltration failure of the peritoneum, which restricts the long-term application of peritoneal dialysis (PD). This study aimed to investigate the therapeutic effects and mechanisms of bone marrow mesenchymal stem cells-derived exosomes (BMSC-Exos) on PF in response to PD.

Methods: Small RNA sequencing analysis of BMSC-Exos was performed by second-generation sequencing.

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Article Synopsis
  • This study examined how common carbapenem-resistant Enterobacterales (CRE) infections and colonizations are in intensive care unit (ICU) patients and what factors contribute to their presence at admission and during the hospital stay.
  • Conducted across 24 ICUs in Anhui, China, the research involved screening patients and applying statistical analysis to identify risk factors linked to CRE colonization/infection.
  • Findings revealed that 5.9% of patients had CRE at admission and 8.5% acquired it during their ICU stay, with several identified risk factors including prior hospital transfers, recent antibiotic exposure, and prolonged ICU stays.
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Objectives: Photobiomodulation (PBM) is widely used in clinical therapy, and is an effective approach to resist the bacterial infection of the cutaneous wound and modulate the wound healing process. Due to the several detriments of lasers, Red & Blue LED light (RBLL) may be a more viable light source. This study is aimed to evaluate and compare the therapeutic effect of RBLL light on different multi-drug resistant (MDR) bacteria in vitro and male Sprague-Dawley (SD) rat refractory MDR infection wound model in vivo.

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