Publications by authors named "Wen-Wei Hsiao"

is a highly destructive fungus that causes brown root disease in trees, leading to decay and death. In Taiwan, five prized woods-, var. , var.

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(Cupressaceae) is one of the five precious woods of Taiwan. In this study, we investigated the anti-melanogenic activity of wood essential oil (CFEO) and its bioactive components in vitro. Initially, CFEO exhibited strong mushroom tyrosinase activity in the cell-free mushroom tyrosinase assay system with an IC value of 2.

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Estrogens are among the most concerned emerging contaminants in the wastewater treatment effluent due to their sexual disruption in aquatic wildlife. The use of microalgae for secondary wastewater effluent polishing is a promising approach due to the economic benefit and value-added products. In this study, three microalgae species, including Selenastrum capricornutum, Scenedesmus quadricauda and Chlorella vulgaris were selected to conduct batch experiments to examine important mechanisms, especially the role of algal extracellular organic matter (AEOM) on two selected estrogens (17β-estradiol, E2 and 17α-ethynylestradiol, EE2) removal.

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Antcins are unique phytosterols isolated from A. cinnamomea and A. salmomea, which are the endemic fungus of Taiwan.

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Introduction: Tamoxifen, an anti-oestrogenic drug for estrogen receptor positive (ER+) breast cancer, was observed to stimulate tumor growth or drug resistance in patients. Antrodia cinnamomea (AC), a precious medicinal fungus has been traditionally used as a folk remedy for cancers in Asian countries. The objective of this study was to investigate the bioefficacy and the underlying molecular mechanisms of the AC fruiting bodies extracts (AC-3E) against human ER+ T47D breast cancer cells, and compare the effect with that of tamoxifen.

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Article Synopsis
  • Antrodia cinnamomea and Antrodia salmonea are two edible mushrooms from Taiwan with different metabolites and health benefits, with A. cinnamomea recognized for its significant health promoting activities.
  • The study identified key volatile compounds and ergostane- and lanostane-type triterpenoids in both mushrooms, noting that A. cinnamomea contains the highest levels of (R,S)-antcin B, while A. salmonea has (R,S)-antcin C as its major compound.
  • A. salmonea exhibited greater anti-inflammatory activity compared to A. cinnamomea, but was found to be more cytotoxic, highlighting the need for further research on its safety and
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Antrodia cinnamomea is a precious edible fungus endemic to Taiwan that has long been used as a folk remedy for health promotion and for treating various diseases. In this study, an index of 13 representative metabolites from the ethanol extract of A. cinnamomea fruiting body was established for use in quality evaluation.

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The fungus Taiwanofungus camphoratus is commonly used for medicinal purposes in Taiwan. It is used as a detoxicant for food poisoning and considered to be a precious folk medicine for hepatoprotection and anti-inflammation. In this study, a lipopolysaccaride (LPS)-challenged ICR mouse acute inflammation model and a LPS-induced macrophage model were used to evaluate the anti-inflammatory activity of T.

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