Publications by authors named "Wen-Shen Gu"
Body mass index (BMI) has been associated with a risk of esophageal cancer. However, the influence of BMI and BMI loss on people with esophageal cancer that were treated with different therapies has not been described in China. In total, 615 consecutive patients that underwent esophagectomy and/or chemotherapy/radiotherapy were classified according to the Asian-specific BMI (kg/m) cutoff values.
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- - The study analyzed the prognostic significance of the albumin-to-globulin ratio (AGR) and its relationship with fibrinogen in 447 patients with resectable esophageal squamous cell carcinoma (ESCC) who had surgery.
- - Findings indicated that lower AGR and higher C-reactive protein (CRP) levels were associated with significantly reduced 5-year survival rates across various patient subgroups, emphasizing their potential as clinical prognostic factors.
- - Additionally, a notable negative correlation was observed between AGR and fibrinogen levels, suggesting that patients with lower AGR tend to have higher fibrinogen, further highlighting the importance of these measurements in assessing patient outcomes.
Background: Noninvasive tools for the prognosis of ESCC are urgently needed. To this end, serum coagulation tests have been researched in some cancers, but the prognostic value of the TT in ESCC has not been described.
Methods: The levels of pre-treatment serum coagulation markers (including the PT, APTT, PTA, INR, fibrinogen level, TT and PLT) were retrospectively analyzed in 204 patients with ESCC who underwent surgical resection at our department and in 200 healthy controls, and the two groups were compared.