Publications by authors named "Wen-Sen Huang"

Liver fibrosis is a critical factor in the advancement of nonalcoholic fatty liver disease towards cirrhosis. There is limited research exploring the association between obstructive sleep apnea (OSA) and liver fibrosis among community populations. The present study aimed to assess the association between sleep apnea (SA) and liver fibrosis based on the National Health and Nutrition Examination Survey (NHANES).

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Article Synopsis
  • Alzheimer's disease (AD) is a progressive brain disorder characterized by memory impairment and cognitive decline, with tau protein being a key factor in its development.
  • A meta-analysis evaluated the relationship between obstructive sleep apnea (OSA) and levels of circulating tau proteins, using data from seven studies with a total of 539 participants.
  • Results showed significantly higher levels of both total tau (T-tau) and phosphorylated tau (P-tau) in OSA patients compared to controls, indicating a potential link, but further research with larger sample sizes is needed to confirm these findings.
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We developed a high-throughput bead-based suspension array for simultaneous detection of 20 respiratory tract pathogens in clinical specimens. Pathogen-specific genes were amplified and hybridized to probes coupled to carboxyl-encoded microspheres. Fluorescence intensities generated via the binding of phycoerythrin-conjugated streptavidin with biotin-labeled targets were measured by the Luminex 100 bead-based suspension array system.

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