Publications by authors named "Wen-Qin Yuan"
Astrocytes have countless links with neurons. Previously, astrocytes were only considered a scaffold of neurons; in fact, astrocytes perform a variety of functions, including providing support for neuronal structures and energy metabolism, offering isolation and protection and influencing the formation, function and elimination of synapses. Because of these functions, astrocytes play an critical role in central nervous system (CNS) diseases.
View Article and Find Full Text PDF[Research progress on activities and mechanisms of anti-hepatitis B virus drugs].
Zhongguo Zhong Yao Za Zhi
June 2022
Article Synopsis
- Hepatitis B virus (HBV) is a highly infectious pathogen causing significant health issues globally, affecting individuals' quality of life.
- Current anti-HBV treatments in Western medicine primarily involve nucleosides and interferons, but both have limitations such as drug resistance and serious side effects.
- Traditional Chinese medicine offers alternative treatments through single herbs and herbal compounds, and combining medications from both Western and traditional approaches may enhance effectiveness and reduce adverse effects.
Primary malignant melanoma of the esophagus (PMME) is a rare and aggressive disease with high tendency of metastasis. To characterize the genetic basis and intratumor heterogeneity of PMME, we performed multiregion exome sequencing and whole genome SNP array genotyping of 12 samples obtained from a patient with PMME. High intratumor heterogeneity was observed in both somatic mutation and copy-number alteration levels.
View Article and Find Full Text PDFAim: To investigate the protective effects and mechanisms of baicalin and octreotide on hepatic injury in rats with severe acute pancreatitis (SAP).
Methods: The SAP rat models were prepared and randomly assigned to the model control group, baicalin treated group, and octreotide treated group while other healthy rats were assigned to the sham-operated group. Rat mortality, levels of ALT, AST, liver and pancreas pathological changes in all groups were observed at 3, 6 and 12 h after operation.