Publications by authors named "Wen-Qian Duan"
Article Synopsis
- Postoperative ileus (POI) is a common issue after abdominal surgeries that negatively affects patient wellbeing; Kuanchang-Shu granule (KCSG) has shown promise in treating POI but its mechanisms are not fully understood.
- Researchers identified 246 chemical ingredients in KCSG and used network pharmacology to find 41 key ingredients, 24 important targets, and 15 signaling pathways related to its effectiveness against POI.
- Testing on a rat model demonstrated that KCSG helps repair intestinal damage and improves gastrointestinal function, with findings suggesting the AKT/eNOS/HSP90AA1 signaling pathway plays a significant role in its protective effects.
