Publications by authors named "Wen-Qi Ding"

Article Synopsis
  • This study examined choroidal thickness (CT) and blood flow in children aged 8-15 with unilateral myopic anisometropia (UMA), focusing on how these factors relate to ocular growth and myopia progression.
  • Researchers measured various ocular metrics in 98 children, using advanced imaging techniques to categorize choroidal features in different regions of the eye.
  • Findings revealed that myopic eyes exhibited significantly lower CT and blood flow parameters compared to non-myopic eyes, suggesting that these choroidal changes may play a role in the progression of myopia in these children.
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Perfect matching of an assembled physical sequence to a specified designed sequence is crucial to verify design principles in genome synthesis. We designed and de novo synthesized 536,024-base pair chromosome synV in the "Build-A-Genome China" course. We corrected an initial isolate of synV to perfectly match the designed sequence using integrative cotransformation and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9)-mediated editing in 22 steps; synV strains exhibit high fitness under a variety of culture conditions, compared with that of wild-type V strains.

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