Publications by authors named "Wen-Peng Hu"
Article Synopsis
- Sepsis can lead to serious complications like acute kidney injury (AKI) and acute lung injury (ALI), for which there are currently no effective drug treatments.
- This study focuses on a newly developed NF-κB inhibitor called 270, evaluating its anti-inflammatory effects in both lab tests and mouse models of AKI and ALI induced by LPS.
- Results indicate that 270 significantly reduces inflammation, improves kidney and lung health, and may serve as a potential therapeutic option for treating LPS-induced AKI and ALI in the future.
The fungal strains are a kind of psychrophilic pathogenic fungi that are ubiquitously distributed in Antarctica, while the studies of their secondary metabolites are infrequent. Systematic research of the metabolites of the fungus sp. HSX2#-11 led to the isolation of six new tremulane sesquiterpenoids pseudotremulanes A-F (-), combined with one known analog 11,12-epoxy-12β-hydroxy-1-tremulen-5-one (), and five known steroids (-).
View Article and Find Full Text PDFThe species is known as a psychrophilic pathogenic fungus which is ubiquitously distributed in Antarctica. While the studies of its secondary metabolites are infrequent. Systematic research of the metabolites of the Antarctic fungus sp.
View Article and Find Full Text PDFThe species is known as a psychrophilic pathogenic fungus with a ubiquitous distribution in Antarctica. Meanwhile, the study of its secondary metabolites is infrequent. Systematic research of the metabolites of the fungus sp.
View Article and Find Full Text PDF