Publications by authors named "Wen-Long Zha"
Plant-derived labdane-related diterpenoids (LRDs) represent a large group of terpenoids. LRDs possess either a labdane-type bicyclic core structure or more complex ring systems derived from labdane-type skeletons, such as abietane, pimarane, kaurane, etc. Due to their various pharmaceutical activities and unique properties, many of LRDs have been widely used in pharmaceutical, food and perfume industries.
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- Sandalwood essential oil, rich in sesquiterpenoids like santalol, is used in natural medicine, perfumery, and food, but its natural sources are being overexploited.
- The review discusses biosynthetic enzymes involved in producing santalene and santalol, focusing on specific enzymes like santalene synthases (STSs) and cytochrome P450 monooxygenases (CYPs).
- It highlights advances in using biotechnology and metabolic engineering to produce these compounds in other organisms, aiming to support sustainable production methods.